IT7950847A0 - Derivati amminici dotati di attivi ta' farmacologica e procedimento per la loro preparazione - Google Patents

Derivati amminici dotati di attivi ta' farmacologica e procedimento per la loro preparazione

Info

Publication number
IT7950847A0
IT7950847A0 IT7950847A IT5084779A IT7950847A0 IT 7950847 A0 IT7950847 A0 IT 7950847A0 IT 7950847 A IT7950847 A IT 7950847A IT 5084779 A IT5084779 A IT 5084779A IT 7950847 A0 IT7950847 A0 IT 7950847A0
Authority
IT
Italy
Prior art keywords
taxes
procedure
preparation
amino derivatives
pharmacological active
Prior art date
Application number
IT7950847A
Other languages
English (en)
Other versions
IT1164761B (it
Inventor
John Watson Clitherow
Barry John Price
John Bradshaw
Michael Martin-Smith
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of IT7950847A0 publication Critical patent/IT7950847A0/it
Application granted granted Critical
Publication of IT1164761B publication Critical patent/IT1164761B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/28Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40Radicals substituted by oxygen atoms
    • C07D307/42Singly bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT50847/79A 1978-11-16 1979-11-16 Derivati amminci dotati di attivita' farmacologica e procedimento per la loro preparazione IT1164761B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7844777 1978-11-16

Publications (2)

Publication Number Publication Date
IT7950847A0 true IT7950847A0 (it) 1979-11-16
IT1164761B IT1164761B (it) 1987-04-15

Family

ID=10501093

Family Applications (1)

Application Number Title Priority Date Filing Date
IT50847/79A IT1164761B (it) 1978-11-16 1979-11-16 Derivati amminci dotati di attivita' farmacologica e procedimento per la loro preparazione

Country Status (13)

Country Link
US (3) US4264614A (it)
JP (1) JPS5581838A (it)
AU (1) AU538513B2 (it)
BE (1) BE880066A (it)
CH (1) CH644347A5 (it)
DE (1) DE2946332A1 (it)
DK (1) DK489279A (it)
ES (1) ES486071A1 (it)
FR (1) FR2446829A1 (it)
IT (1) IT1164761B (it)
NL (1) NL7908398A (it)
SE (1) SE7909507L (it)
ZA (1) ZA796169B (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5021429A (en) * 1977-05-17 1991-06-04 Allen & Hansburys Limited Pharmacologically active aminoalkylphenyl compounds and their use
JPS5681578A (en) * 1979-12-07 1981-07-03 Shionogi & Co Ltd Novel thioalkyl amide derivative
YU53681A (en) * 1980-03-08 1983-12-31 Smith Kline French Lab Process for obtaining 5-dimethylamino-methyl-2-furane methanol
DE3168031D1 (en) * 1980-07-30 1985-02-14 Ici Plc Guanidine derivatives
JPS57102852A (en) * 1980-12-19 1982-06-26 Shionogi & Co Ltd Dicarboxylic acid diamide
DE3245482A1 (de) * 1982-12-08 1984-06-14 Byk-Mallinckrodt Chemische Produkte Gmbh, 4230 Wesel Entschaeumer und verfahren zu ihrer herstellung
US4665172A (en) * 1983-01-28 1987-05-12 Ube Industries, Ltd. Process for producing heterocyclic compound having nitromethylene group as the side chain group
US4946842A (en) * 1985-07-05 1990-08-07 Smith Kline & French Laboratories Limited Novel guanidino pyridazinones as cardiac stimulants
US4950789A (en) * 1989-01-25 1990-08-21 The Dow Chemical Company Aromatic polyalkyleneoxy polyamines containing amioncarbonyl or aminothiocarbonyl moieties and a compatible mixture of high and low molecular weight polyols made therefrom
JP2002529503A (ja) * 1998-11-17 2002-09-10 ニトロメッド,インク. ニトロソ化及びニトロシル化h2リセプターアンタゴニスト化合物及び組成物並びにその利用方法
US20230349922A1 (en) 2020-08-11 2023-11-02 Université De Strasbourg H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1493931A (en) 1974-02-07 1977-11-30 Smith Kline French Lab Guanidines isothioureas and thioureas
IL52544A0 (en) * 1976-07-28 1977-10-31 Smith Kline French Lab Alpha,omega-bis (heterocyclicguanidino) alkane derivative
ZA774220B (en) 1976-07-28 1978-06-28 Smith Kline French Lab Pharmacologically active compounds
ZA774221B (en) 1976-07-28 1978-06-28 Smith Kline French Lab Pharmacologically active compounds
GB1565966A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
DE2719798A1 (de) 1977-05-03 1978-11-16 Uniroyal Ag Hochbelastbarer stahlkord-guertelreifen, insbesondere fuer lastkraftwagen, schwer- und/oder grossfahrzeuge mit einer mindestens einlagigen radialkarkasse, vorzugsweise aus stahlkord, und einer mehrlagigen guertelartigen verstaerkung, welche wenigstens eine faltlage aus stahlkord und wenigstens eine weitere ungefaltete lage aus textilkord aufweist

Also Published As

Publication number Publication date
NL7908398A (nl) 1980-05-20
CH644347A5 (fr) 1984-07-31
SE7909507L (sv) 1980-05-17
DK489279A (da) 1980-05-17
IT1164761B (it) 1987-04-15
BE880066A (fr) 1980-03-17
JPS5581838A (en) 1980-06-20
ZA796169B (en) 1981-04-29
US4366164A (en) 1982-12-28
ES486071A1 (es) 1980-09-01
AU538513B2 (en) 1984-08-16
DE2946332A1 (de) 1980-05-29
US4264614A (en) 1981-04-28
US4317819A (en) 1982-03-02
FR2446829A1 (fr) 1980-08-14
AU5291279A (en) 1980-05-22
FR2446829B1 (it) 1983-04-29

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