IT7809692A0 - Procedimento per la produzione di vincadifformina - Google Patents
Procedimento per la produzione di vincadifforminaInfo
- Publication number
- IT7809692A0 IT7809692A0 IT7809692A IT969278A IT7809692A0 IT 7809692 A0 IT7809692 A0 IT 7809692A0 IT 7809692 A IT7809692 A IT 7809692A IT 969278 A IT969278 A IT 969278A IT 7809692 A0 IT7809692 A0 IT 7809692A0
- Authority
- IT
- Italy
- Prior art keywords
- vincadifformin
- procedure
- production
- Prior art date
Links
- GIGFIWJRTMBSRP-UHFFFAOYSA-N DL-Vincadifformin Natural products C1C(C(=O)OC)=C2NC3=CC=CC=C3C22CCN3CCCC1(CC)C23 GIGFIWJRTMBSRP-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/30—Compounds having groups
- C07C43/313—Compounds having groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/48—Preparation of compounds having groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/30—Compounds having groups
- C07C43/315—Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/865,657 US4154943A (en) | 1977-12-29 | 1977-12-29 | Preparation of vincadifformine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT7809692A0 true IT7809692A0 (it) | 1978-12-29 |
| IT1109011B IT1109011B (it) | 1985-12-16 |
Family
ID=25345973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT09692/78A IT1109011B (it) | 1977-12-29 | 1978-12-29 | Procedimento per la produzione di vincadifformina |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4154943A (it) |
| JP (1) | JPS5498800A (it) |
| BE (1) | BE873136A (it) |
| CA (1) | CA1098903A (it) |
| ES (1) | ES476504A1 (it) |
| FR (1) | FR2413391A1 (it) |
| GB (1) | GB2011899B (it) |
| HU (1) | HU180905B (it) |
| IT (1) | IT1109011B (it) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4283536A (en) * | 1977-12-29 | 1981-08-11 | University Of Vermont | Preparation of vincadifformine and related derivatives |
| US4267330A (en) * | 1978-08-24 | 1981-05-12 | Omnium Chimique Societe Anonyme | Process for the synthesis of vincadifformine and related derivatives |
| FR2434166A2 (fr) * | 1978-08-24 | 1980-03-21 | Omnium Chimique Sa | Procede de preparation de vincadifformine et derives similaires |
| US4220774A (en) * | 1978-10-26 | 1980-09-02 | Omnium Chimique | Vincadifformine synthesis process |
| US4362739A (en) * | 1981-05-04 | 1982-12-07 | S.A. Omnichem | Pyrrolo(2,3-d)carbazole derivatives, compositions and use |
| US4428880A (en) | 1981-05-04 | 1984-01-31 | S.A. Omnichem | Azepino[4,5-d]indole derivatives and preparation thereof |
| LU85894A1 (fr) * | 1985-05-10 | 1986-12-05 | Omnichem Sa | Derives de 1,2,3,4,5,6-hexahydro-azepino (4,5-b) indole leur preparation,composes intermediaires,et leur application en therapeutique |
| CO5180550A1 (es) | 1999-04-19 | 2002-07-30 | Smithkline Beecham Corp | Inhibidores de fab i |
| CO5370679A1 (es) | 1999-06-01 | 2004-02-27 | Smithkline Beecham Corp | Inhibidores fab 1 |
| US6762201B1 (en) | 1999-10-08 | 2004-07-13 | Affinium Pharmaceuticals, Inc. | Fab I inhibitors |
| US6730684B1 (en) | 1999-10-08 | 2004-05-04 | Affinium Pharmaceuticals, Inc. | Fab I inhibitors |
| ECSP003699A (es) | 1999-10-08 | 2002-04-23 | Smithkline Beecham Corp | Inhibidores de fab i |
| DE60230934D1 (de) * | 2001-04-06 | 2009-03-05 | Affinium Pharm Inc | Fab-i-inhibitoren |
| EP1575951B1 (en) * | 2002-12-06 | 2014-06-25 | Debiopharm International SA | Heterocyclic compounds, methods of making them and their use in therapy |
| WO2004082586A2 (en) | 2003-03-17 | 2004-09-30 | Affinium Pharmaceuticals, Inc. | Phamaceutical compositions comprising inhibitors of fab i and further antibiotics |
| US8450307B2 (en) * | 2004-06-04 | 2013-05-28 | Affinium Pharmaceuticals, Inc. | Therapeutic agents, and methods of making and using the same |
| CA2632476A1 (en) * | 2005-12-05 | 2007-06-14 | Affinium Pharmaceuticals, Inc. | Heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents |
| EP2687533B1 (en) | 2006-07-20 | 2017-07-19 | Debiopharm International SA | Acrylamide derivatives as FAB I inhibitors |
| WO2008098374A1 (en) * | 2007-02-16 | 2008-08-21 | Affinium Pharmaceuticals, Inc. | Salts, prodrugs and polymorphs of fab i inhibitors |
| US20130178618A1 (en) | 2012-01-10 | 2013-07-11 | William Allen Boulanger | Novel pharmaceutical intermediates and methods for preparing the same |
| KR101720885B1 (ko) | 2012-06-19 | 2017-03-28 | 데비오팜 인터네셔날 에스 에이 | (e)-n-메틸-n-((3-메틸벤조푸란-2-일)메틸)-3-(7-옥소-5,6,7,8-테트라히드로-1,8-나프티리딘-3-일)아크릴아미드의전구약물 유도체 |
| RS61312B1 (sr) | 2016-02-26 | 2021-02-26 | Debiopharm Int Sa | Lek za lečenje infekcija dijabetskog stopala |
| CN107216328A (zh) * | 2017-07-06 | 2017-09-29 | 贵州医科大学 | 一种α‑卡波林类化合物的合成方法 |
| MY203711A (en) | 2019-02-14 | 2024-07-15 | Debiopharm Int Sa | Afabicin formulation, method for making the same and uses thereof |
| JP7418475B2 (ja) | 2019-06-14 | 2024-01-19 | デバイオファーム インターナショナル エス．エー． | バイオフィルムが関与する細菌感染症を治療するための医薬及びその使用 |
| US12116372B1 (en) | 2023-12-14 | 2024-10-15 | William Allen Boulanger | Process for preparing methyl 3-bromo-2-(2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)propanoate |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE811614A (en) | 1974-02-27 | 1974-06-17 | (-) Vincadifformine prodn. - by hemisynthesis starting from vindolinine which is obtd. from catharantus roseus |
-
1977
- 1977-12-29 US US05/865,657 patent/US4154943A/en not_active Expired - Lifetime
-
1978
- 1978-12-28 CA CA318,789A patent/CA1098903A/en not_active Expired
- 1978-12-28 BE BE192612A patent/BE873136A/xx not_active IP Right Cessation
- 1978-12-28 HU HU78OI222A patent/HU180905B/hu not_active IP Right Cessation
- 1978-12-29 FR FR7836935A patent/FR2413391A1/fr active Granted
- 1978-12-29 GB GB7850201A patent/GB2011899B/en not_active Expired
- 1978-12-29 ES ES476504A patent/ES476504A1/es not_active Expired
- 1978-12-29 JP JP16439678A patent/JPS5498800A/ja active Granted
- 1978-12-29 IT IT09692/78A patent/IT1109011B/it active
Also Published As
| Publication number | Publication date |
|---|---|
| FR2413391B1 (it) | 1983-08-05 |
| CA1098903A (en) | 1981-04-07 |
| JPS6215555B2 (it) | 1987-04-08 |
| IT1109011B (it) | 1985-12-16 |
| GB2011899B (en) | 1982-05-26 |
| US4154943A (en) | 1979-05-15 |
| JPS5498800A (en) | 1979-08-03 |
| FR2413391A1 (fr) | 1979-07-27 |
| BE873136A (fr) | 1979-06-28 |
| HU180905B (en) | 1983-05-30 |
| ES476504A1 (es) | 1979-11-16 |
| GB2011899A (en) | 1979-07-18 |
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