IT201700115761A1 - Bioreattore per la ricellularizzazione e la stimolazione meccanica del diaframma - Google Patents

Bioreattore per la ricellularizzazione e la stimolazione meccanica del diaframma

Info

Publication number
IT201700115761A1
IT201700115761A1 IT102017000115761A IT201700115761A IT201700115761A1 IT 201700115761 A1 IT201700115761 A1 IT 201700115761A1 IT 102017000115761 A IT102017000115761 A IT 102017000115761A IT 201700115761 A IT201700115761 A IT 201700115761A IT 201700115761 A1 IT201700115761 A1 IT 201700115761A1
Authority
IT
Italy
Prior art keywords
rebellarization
bioreactor
diaphragm
mechanical stimulation
stimulation
Prior art date
Application number
IT102017000115761A
Other languages
English (en)
Inventor
Martina Piccoli
Piero Pavan
Original Assignee
St Di Ricerca Pediatrica Citta Della Speranza
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by St Di Ricerca Pediatrica Citta Della Speranza filed Critical St Di Ricerca Pediatrica Citta Della Speranza
Priority to IT102017000115761A priority Critical patent/IT201700115761A1/it
Priority to EP18200059.6A priority patent/EP3470511A1/en
Publication of IT201700115761A1 publication Critical patent/IT201700115761A1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/58—Reaction vessels connected in series or in parallel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Mechanical Engineering (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
IT102017000115761A 2017-10-13 2017-10-13 Bioreattore per la ricellularizzazione e la stimolazione meccanica del diaframma IT201700115761A1 (it)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IT102017000115761A IT201700115761A1 (it) 2017-10-13 2017-10-13 Bioreattore per la ricellularizzazione e la stimolazione meccanica del diaframma
EP18200059.6A EP3470511A1 (en) 2017-10-13 2018-10-12 Bioreactor for the recellularization and mechanical stimulation of a diaphragm

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102017000115761A IT201700115761A1 (it) 2017-10-13 2017-10-13 Bioreattore per la ricellularizzazione e la stimolazione meccanica del diaframma

Publications (1)

Publication Number Publication Date
IT201700115761A1 true IT201700115761A1 (it) 2019-04-13

Family

ID=61224320

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102017000115761A IT201700115761A1 (it) 2017-10-13 2017-10-13 Bioreattore per la ricellularizzazione e la stimolazione meccanica del diaframma

Country Status (2)

Country Link
EP (1) EP3470511A1 (it)
IT (1) IT201700115761A1 (it)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112501019A (zh) * 2020-12-03 2021-03-16 广州迈普再生医学科技股份有限公司 一种多功能生物反应器

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111849771B (zh) * 2020-07-31 2023-03-28 中国人民解放军空军军医大学 一种对含细胞的培养物进行负压和力学刺激的培养装置

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10249903A1 (de) * 2002-10-22 2004-05-19 Cytonet Gmbh & Co. Kg Mechanischer Bioreaktor
EP2039756A1 (en) * 2006-07-10 2009-03-25 Takagi Industrial Co., Ltd. Cell or tissue cultivation apparatus and method of cultivation
DE102009057698A1 (de) * 2009-12-03 2011-06-09 Martin-Luther-Universität Halle-Wittenberg Zweikammerkultivierungssystem mit elastischer, poröser Membran zur uniaxialen mechanischen Stimulation von Epithelzellen und Epithelzellverbänden für die Testung endogener und exogener Faktoren
US20120276622A1 (en) * 2009-05-08 2012-11-01 Chang Gung University Apparatus and method for high-throughput micro-cell culture with mechanical stimulation

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10249903A1 (de) * 2002-10-22 2004-05-19 Cytonet Gmbh & Co. Kg Mechanischer Bioreaktor
EP2039756A1 (en) * 2006-07-10 2009-03-25 Takagi Industrial Co., Ltd. Cell or tissue cultivation apparatus and method of cultivation
US20120276622A1 (en) * 2009-05-08 2012-11-01 Chang Gung University Apparatus and method for high-throughput micro-cell culture with mechanical stimulation
DE102009057698A1 (de) * 2009-12-03 2011-06-09 Martin-Luther-Universität Halle-Wittenberg Zweikammerkultivierungssystem mit elastischer, poröser Membran zur uniaxialen mechanischen Stimulation von Epithelzellen und Epithelzellverbänden für die Testung endogener und exogener Faktoren

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GUBAREVA ELENA A ET AL: "Orthotopic transplantation of a tissue engineered diaphragm in rats", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 77, 14 November 2015 (2015-11-14), pages 320 - 335, XP029337986, ISSN: 0142-9612, DOI: 10.1016/J.BIOMATERIALS.2015.11.020 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112501019A (zh) * 2020-12-03 2021-03-16 广州迈普再生医学科技股份有限公司 一种多功能生物反应器
CN112501019B (zh) * 2020-12-03 2023-10-31 广州迈普再生医学科技股份有限公司 一种多功能生物反应器

Also Published As

Publication number Publication date
EP3470511A1 (en) 2019-04-17

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