IT1312077B1 - Polipeptidi ad attivita' antiangiogenica. - Google Patents

Polipeptidi ad attivita' antiangiogenica.

Info

Publication number
IT1312077B1
IT1312077B1 IT1999MI000777A ITMI990777A IT1312077B1 IT 1312077 B1 IT1312077 B1 IT 1312077B1 IT 1999MI000777 A IT1999MI000777 A IT 1999MI000777A IT MI990777 A ITMI990777 A IT MI990777A IT 1312077 B1 IT1312077 B1 IT 1312077B1
Authority
IT
Italy
Prior art keywords
antiangiogenic activity
activity polypeptides
polypeptides
antiangiogenic
activity
Prior art date
Application number
IT1999MI000777A
Other languages
English (en)
Inventor
Francesco Chillemi
Pierangelo Francescato
Marina Ziche
Original Assignee
Univ Degli Studi Milano
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Degli Studi Milano filed Critical Univ Degli Studi Milano
Priority to IT1999MI000777A priority Critical patent/IT1312077B1/it
Priority to PCT/EP2000/003236 priority patent/WO2000063249A1/en
Priority to US09/958,489 priority patent/US6921749B1/en
Priority to AU45473/00A priority patent/AU4547300A/en
Priority to CA002369961A priority patent/CA2369961A1/en
Priority to MXPA01010302A priority patent/MXPA01010302A/es
Priority to EP00926869A priority patent/EP1169351A1/en
Priority to JP2000612335A priority patent/JP2002544124A/ja
Publication of ITMI990777A1 publication Critical patent/ITMI990777A1/it
Application granted granted Critical
Publication of IT1312077B1 publication Critical patent/IT1312077B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
IT1999MI000777A 1999-04-15 1999-04-15 Polipeptidi ad attivita' antiangiogenica. IT1312077B1 (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT1999MI000777A IT1312077B1 (it) 1999-04-15 1999-04-15 Polipeptidi ad attivita' antiangiogenica.
PCT/EP2000/003236 WO2000063249A1 (en) 1999-04-15 2000-04-11 Polypeptides derived from endostatin exhibiting antiangiogenic activity
US09/958,489 US6921749B1 (en) 1999-04-15 2000-04-11 Polypeptides derived from endostatin exhibiting antiangiogenic activity
AU45473/00A AU4547300A (en) 1999-04-15 2000-04-11 Polypeptides derived from endostatin exhibiting antiangiogenic activity
CA002369961A CA2369961A1 (en) 1999-04-15 2000-04-11 Polypeptides derived from endostatin exhibiting antiangiogenic activity
MXPA01010302A MXPA01010302A (es) 1999-04-15 2000-04-11 Polipeptidos derivados de endostatina que presenta actividad antiangiogenica.
EP00926869A EP1169351A1 (en) 1999-04-15 2000-04-11 Polypeptides derived from endostatin exhibiting antiangiogenic activity
JP2000612335A JP2002544124A (ja) 1999-04-15 2000-04-11 抗血管新生活性を示すエンドスタチン由来のポリペプチド

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI000777A IT1312077B1 (it) 1999-04-15 1999-04-15 Polipeptidi ad attivita' antiangiogenica.

Publications (2)

Publication Number Publication Date
ITMI990777A1 ITMI990777A1 (it) 2000-10-15
IT1312077B1 true IT1312077B1 (it) 2002-04-04

Family

ID=11382727

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1999MI000777A IT1312077B1 (it) 1999-04-15 1999-04-15 Polipeptidi ad attivita' antiangiogenica.

Country Status (8)

Country Link
US (1) US6921749B1 (it)
EP (1) EP1169351A1 (it)
JP (1) JP2002544124A (it)
AU (1) AU4547300A (it)
CA (1) CA2369961A1 (it)
IT (1) IT1312077B1 (it)
MX (1) MXPA01010302A (it)
WO (1) WO2000063249A1 (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1401480B1 (en) * 2001-02-22 2012-11-28 Novartis AG Viral vectors encoding endostatin in the treatment of ocular neovascularization
ITMI20010394A1 (it) * 2001-02-27 2002-08-27 Univ Degli Studi Milano Peptidi ad attivita' antiangiogenica
DE602004017487D1 (de) 2003-08-29 2008-12-11 Childrens Medical Center Antiangiogene peptide vom n-terminus von endostatin
US7524811B2 (en) 2003-08-29 2009-04-28 Children's Medical Center Corporation Anti-angiogenic peptides from the N-terminus of endostatin
ITMI20040364A1 (it) * 2004-02-27 2004-05-27 Francesco Chillemi Peptidi ad attivita' antiangiogenica e antitumorale
CN110078811B (zh) * 2018-01-25 2022-02-11 中国医学科学院医药生物技术研究所 一种具有抗肿瘤活性的多肽imb-p1及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1202932A (zh) * 1995-10-23 1998-12-23 儿童医学中心公司 治疗用抗血管生成的组合物和方法
EP1037983A1 (en) * 1997-12-08 2000-09-27 Beth Israel Deaconess Medical Center Mutants of endostatin, "em 1" having anti-angiogenic activity and methods of use thereof
AU3199999A (en) * 1998-03-24 1999-10-18 Children's Medical Center Corporation Endostatin derived peptides with anti-angiogenic and anti-cancer activity
CA2372053C (en) * 1999-04-28 2008-09-02 Board Of Regents, The University Of Texas System Compositions and methods for cancer treatment by selectively inhibiting vegf

Also Published As

Publication number Publication date
AU4547300A (en) 2000-11-02
JP2002544124A (ja) 2002-12-24
CA2369961A1 (en) 2000-10-26
MXPA01010302A (es) 2002-09-18
US6921749B1 (en) 2005-07-26
EP1169351A1 (en) 2002-01-09
WO2000063249A1 (en) 2000-10-26
ITMI990777A1 (it) 2000-10-15

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