IT1309593B1 - Composti eterociclici ad attivita' antitumorale. - Google Patents
Composti eterociclici ad attivita' antitumorale.Info
- Publication number
- IT1309593B1 IT1309593B1 IT1999MI000456A ITMI990456A IT1309593B1 IT 1309593 B1 IT1309593 B1 IT 1309593B1 IT 1999MI000456 A IT1999MI000456 A IT 1999MI000456A IT MI990456 A ITMI990456 A IT MI990456A IT 1309593 B1 IT1309593 B1 IT 1309593B1
- Authority
- IT
- Italy
- Prior art keywords
- heterocyclic compounds
- tumor activity
- tumor
- activity
- heterocyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/36—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/38—2-Pyrrolones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/66—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
- Pyrane Compounds (AREA)
- Pyrrole Compounds (AREA)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1999MI000456A IT1309593B1 (it) | 1999-03-05 | 1999-03-05 | Composti eterociclici ad attivita' antitumorale. |
AU41033/00A AU4103300A (en) | 1999-03-05 | 2000-03-01 | Heterocyclic compounds having antitumor activity |
PCT/EP2000/001721 WO2000053581A2 (en) | 1999-03-05 | 2000-03-01 | Heterocyclic compounds having antitumor activity |
EP00920458A EP1173420A2 (en) | 1999-03-05 | 2000-03-01 | Heterocyclic compounds having antitumor activity |
JP2000604021A JP2002539114A (ja) | 1999-03-05 | 2000-03-01 | 抗腫瘍活性を有する複素環化合物 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1999MI000456A IT1309593B1 (it) | 1999-03-05 | 1999-03-05 | Composti eterociclici ad attivita' antitumorale. |
Publications (2)
Publication Number | Publication Date |
---|---|
ITMI990456A1 ITMI990456A1 (it) | 2000-09-05 |
IT1309593B1 true IT1309593B1 (it) | 2002-01-24 |
Family
ID=11382169
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT1999MI000456A IT1309593B1 (it) | 1999-03-05 | 1999-03-05 | Composti eterociclici ad attivita' antitumorale. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1173420A2 (it) |
JP (1) | JP2002539114A (it) |
AU (1) | AU4103300A (it) |
IT (1) | IT1309593B1 (it) |
WO (1) | WO2000053581A2 (it) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2008000113A (es) | 2005-06-28 | 2008-03-18 | Merck & Co Inc | Agonistas del receptor de niacina, composiciones que contienen tales compuestos y procedimientos para tratamiento. |
EP3350173B1 (en) | 2015-09-18 | 2020-02-12 | Boehringer Ingelheim International GmbH | Stereoselective process |
CN109651310B (zh) * | 2018-12-26 | 2022-07-22 | 华南师范大学 | 一种n-呋喃酮基芳基磺酰肼类衍生物及其制备方法和应用 |
CN113980004B (zh) * | 2021-10-18 | 2023-07-04 | 成都大学 | 一种具有呋喃-2(5h)-酮骨架的化合物及其制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3496187A (en) * | 1967-03-20 | 1970-02-17 | American Home Prod | N-(heterocyclyl)aconamides |
US3472878A (en) * | 1969-01-27 | 1969-10-14 | American Home Prod | N-(hydroxyaryl)aconamides |
DE2108926C3 (de) * | 1971-02-25 | 1980-06-04 | Basf Ag, 6700 Ludwigshafen | Verfahren zur Herstellung von 3-Acyl-4-hydroxy-buten-(2)-saurelactonen |
JP3124373B2 (ja) * | 1992-03-13 | 2001-01-15 | 塩野義製薬株式会社 | 免疫抑制物質 |
US5773459A (en) * | 1995-06-07 | 1998-06-30 | Sugen, Inc. | Urea- and thiourea-type compounds |
CA2222471A1 (en) * | 1996-03-27 | 1997-10-02 | Toray Industries, Inc. | Ketone derivatives and medical application thereof |
CO4970714A1 (es) * | 1997-09-05 | 2000-11-07 | Boehringer Mannheim Gmbh | Derivados ureido y tioureido de 4-amino-2(5h)-furanonas y 4-amino-2(5h) tiofenonas como agentes antitumorales |
-
1999
- 1999-03-05 IT IT1999MI000456A patent/IT1309593B1/it active
-
2000
- 2000-03-01 JP JP2000604021A patent/JP2002539114A/ja active Pending
- 2000-03-01 EP EP00920458A patent/EP1173420A2/en not_active Withdrawn
- 2000-03-01 AU AU41033/00A patent/AU4103300A/en not_active Abandoned
- 2000-03-01 WO PCT/EP2000/001721 patent/WO2000053581A2/en active Search and Examination
Also Published As
Publication number | Publication date |
---|---|
WO2000053581A3 (en) | 2000-12-21 |
JP2002539114A (ja) | 2002-11-19 |
ITMI990456A1 (it) | 2000-09-05 |
EP1173420A2 (en) | 2002-01-23 |
WO2000053581A2 (en) | 2000-09-14 |
AU4103300A (en) | 2000-09-28 |
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