IT1292092B1 - Impiego di derivati eterociclici aromatici azotati nel trattamento topico di affezioni di tessuti epiteliali - Google Patents
Impiego di derivati eterociclici aromatici azotati nel trattamento topico di affezioni di tessuti epitelialiInfo
- Publication number
- IT1292092B1 IT1292092B1 IT97MI001329A ITMI971329A IT1292092B1 IT 1292092 B1 IT1292092 B1 IT 1292092B1 IT 97MI001329 A IT97MI001329 A IT 97MI001329A IT MI971329 A ITMI971329 A IT MI971329A IT 1292092 B1 IT1292092 B1 IT 1292092B1
- Authority
- IT
- Italy
- Prior art keywords
- topical treatment
- epithelial tissues
- aromatic heterocyclic
- heterocyclic derivatives
- nitrogen aromatic
- Prior art date
Links
- 210000000981 epithelium Anatomy 0.000 title abstract 2
- 230000000699 topical effect Effects 0.000 title abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 title 2
- 229910052757 nitrogen Inorganic materials 0.000 title 1
- 206010009900 Colitis ulcerative Diseases 0.000 abstract 2
- 201000004681 Psoriasis Diseases 0.000 abstract 2
- 201000006704 Ulcerative Colitis Diseases 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 210000000936 intestine Anatomy 0.000 abstract 2
- 208000011231 Crohn disease Diseases 0.000 abstract 1
- 206010012438 Dermatitis atopic Diseases 0.000 abstract 1
- 201000008937 atopic dermatitis Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 210000002615 epidermis Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cosmetics (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT97MI001329A IT1292092B1 (it) | 1997-06-05 | 1997-06-05 | Impiego di derivati eterociclici aromatici azotati nel trattamento topico di affezioni di tessuti epiteliali |
| US09/445,219 US6323230B1 (en) | 1997-06-05 | 1998-06-04 | Use of nitrogen heterocyclic aromatic derivatives in the topical treatment of the epithelial tissues diseases |
| PT98937464T PT986386E (pt) | 1997-06-05 | 1998-06-04 | Uso de derivados heterociclicos aromaticos com azoto no tratamento topico de doencas dos tecidos epiteliais |
| DK98937464T DK0986386T3 (da) | 1997-06-05 | 1998-06-04 | Anvendelse af nitrogenheterocycliske, aromatiske derivater til topisk behandling af sygdomme i epitelvævene |
| CA002294547A CA2294547A1 (en) | 1997-06-05 | 1998-06-04 | Use of nitrogen heterocyclic aromatic derivatives in the topical treatment of the epithelial tissues diseases |
| EP98937464A EP0986386B1 (en) | 1997-06-05 | 1998-06-04 | Use of nitrogen heterocyclic aromatic derivatives in the topical treatment of the epithelial tissues diseases |
| JP50160699A JP2002502410A (ja) | 1997-06-05 | 1998-06-04 | 上皮組織疾患の局所治療における窒素複素環式芳香族誘導体の使用 |
| DE69822153T DE69822153T2 (de) | 1997-06-05 | 1998-06-04 | Verwendung von stickstoffhaltigen aromatischen heterozyklusderivaten zur topischen behandlung von epithelerkrankungen |
| AT98937464T ATE260655T1 (de) | 1997-06-05 | 1998-06-04 | Verwendung von stickstoffhaltigen aromatischen heterozyklusderivaten zur topischen behandlung von epithelerkrankungen |
| PCT/EP1998/003497 WO1998055118A2 (en) | 1997-06-05 | 1998-06-04 | Use of nitrogen heterocyclic aromatic derivatives in the topical treatment of the epithelial tissues diseases |
| ES98937464T ES2215315T3 (es) | 1997-06-05 | 1998-06-04 | Uso de derivados aromaticos heterociclicos conteniendo nitrogeno en el tratamiento topico de las enfermedades de los tejidos epiteliales. |
| AU86255/98A AU8625598A (en) | 1997-06-05 | 1998-06-04 | Use of nitrogen heterocyclic aromatic derivatives in the topical treatment of the epithelial tissues diseases |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT97MI001329A IT1292092B1 (it) | 1997-06-05 | 1997-06-05 | Impiego di derivati eterociclici aromatici azotati nel trattamento topico di affezioni di tessuti epiteliali |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI971329A0 ITMI971329A0 (forum.php) | 1997-06-05 |
| ITMI971329A1 ITMI971329A1 (it) | 1998-12-05 |
| IT1292092B1 true IT1292092B1 (it) | 1999-01-25 |
Family
ID=11377302
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT97MI001329A IT1292092B1 (it) | 1997-06-05 | 1997-06-05 | Impiego di derivati eterociclici aromatici azotati nel trattamento topico di affezioni di tessuti epiteliali |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6323230B1 (forum.php) |
| EP (1) | EP0986386B1 (forum.php) |
| JP (1) | JP2002502410A (forum.php) |
| AT (1) | ATE260655T1 (forum.php) |
| AU (1) | AU8625598A (forum.php) |
| CA (1) | CA2294547A1 (forum.php) |
| DE (1) | DE69822153T2 (forum.php) |
| DK (1) | DK0986386T3 (forum.php) |
| ES (1) | ES2215315T3 (forum.php) |
| IT (1) | IT1292092B1 (forum.php) |
| PT (1) | PT986386E (forum.php) |
| WO (1) | WO1998055118A2 (forum.php) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6221897B1 (en) | 1998-06-10 | 2001-04-24 | Aventis Pharma Deutschland Gmbh | Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use |
| WO2002048144A1 (en) | 2000-12-13 | 2002-06-20 | Bayer Aktiengesellschaft | Pyrrolo (2.1-a) dihydroisoquinolines and their use as phosphodiesterase 10a inhibitors |
| WO2003014115A1 (en) * | 2001-08-06 | 2003-02-20 | Bayer Aktiengesellschaft | 3-substituted pyrrolo (2.1-a) isoquinoline derivatives |
| US6797722B2 (en) * | 2002-05-03 | 2004-09-28 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole for the treatment of autoimmune diseases |
| CA2595075A1 (en) * | 2005-01-12 | 2006-07-20 | Matthias Vennemann | Pyrrolodihydroisoquinolines as antiproliferative agents |
| EP2089367B1 (en) | 2006-10-31 | 2011-12-14 | Pfizer Products Inc. | Pyrazoline compounds as mineralocorticoid receptor antagonists |
| PL2465541T3 (pl) | 2007-05-22 | 2018-12-31 | Wyeth Llc | Ulepszone sposoby wytwarzania hydrazydów |
| TWI490214B (zh) * | 2008-05-30 | 2015-07-01 | 艾德克 上野股份有限公司 | 苯或噻吩衍生物及該等作為ｖａｐ－１抑制劑之用途 |
| SG10201909122QA (en) | 2011-10-28 | 2019-11-28 | Lumena Pharmaceuticals Inc | Bile acid recycling inhibitors for treatment of pediatric cholestatic liver diseases |
| MX382960B (es) | 2011-10-28 | 2025-03-13 | Shire Human Genetic Therapies | Inhibidores de la recirculación de ácidos biliares para el tratamiento de hipercolemia y enfermedad hepática colestásica. |
| CN116514801B (zh) * | 2022-01-20 | 2024-11-08 | 四川大学 | 2-苯基-[1,2,4]三唑并[1,5-a]吡啶类化合物、其氮氧化物及用途 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1579352A (en) * | 1977-05-06 | 1980-11-19 | Lepetit Spa | 3,5-disubstituted-1h-1,2,4-triazoles |
| EP0011129B1 (en) * | 1978-10-30 | 1981-11-11 | Gruppo Lepetit S.P.A. | New 1,2,4-triazole derivatives, a process for their manufacture and pharmaceutical compositions containing them |
| FI64151C (fi) * | 1978-10-30 | 1983-10-10 | Lepetit Spa | Nya vid foedelsekontroll av daeggdjur anvaendbara 1h-1,2,4-triatzolderivat |
| US4379155A (en) | 1979-06-11 | 1983-04-05 | Gruppo Lepetit S.P.A. | 3,5-Disubstituted-1H-1,2,4-triazole derivatives |
| AU557034B2 (en) * | 1981-10-20 | 1986-12-04 | Gruppo Lepetit S.P.A. | 3,5-diphenyl-1h-1,2,4-trazoles with contragestational |
| SE9300127L (sv) * | 1993-01-19 | 1994-07-20 | Eyvind Langvad | Tricyliska kondenserade 1,2,4-triazoloderivat användbara såsom antiinflammatoriska medel |
| DE4320801A1 (de) * | 1993-06-23 | 1995-01-05 | Fahlberg List Pharma Gmbh | 2-Hydroxyphenylsubstituierte 1,2,4-Triazole und 1,2,4-Oxadiazole, ihre Verwendung als pharmazeutische Wirkstoffe und sie enthaltende Arzneimittel |
| WO1995013268A1 (en) * | 1993-11-12 | 1995-05-18 | Gyógyszerkutató Intézet Kft. | Ulcer-inhibiting triazole derivatives, pharmaceutical compositions containing them and process for preparing same |
-
1997
- 1997-06-05 IT IT97MI001329A patent/IT1292092B1/it active IP Right Grant
-
1998
- 1998-06-04 DK DK98937464T patent/DK0986386T3/da active
- 1998-06-04 PT PT98937464T patent/PT986386E/pt unknown
- 1998-06-04 US US09/445,219 patent/US6323230B1/en not_active Expired - Fee Related
- 1998-06-04 EP EP98937464A patent/EP0986386B1/en not_active Expired - Lifetime
- 1998-06-04 CA CA002294547A patent/CA2294547A1/en not_active Abandoned
- 1998-06-04 AT AT98937464T patent/ATE260655T1/de not_active IP Right Cessation
- 1998-06-04 DE DE69822153T patent/DE69822153T2/de not_active Expired - Fee Related
- 1998-06-04 WO PCT/EP1998/003497 patent/WO1998055118A2/en active IP Right Grant
- 1998-06-04 ES ES98937464T patent/ES2215315T3/es not_active Expired - Lifetime
- 1998-06-04 JP JP50160699A patent/JP2002502410A/ja not_active Ceased
- 1998-06-04 AU AU86255/98A patent/AU8625598A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002502410A (ja) | 2002-01-22 |
| CA2294547A1 (en) | 1998-12-10 |
| ITMI971329A1 (it) | 1998-12-05 |
| ITMI971329A0 (forum.php) | 1997-06-05 |
| ES2215315T3 (es) | 2004-10-01 |
| DE69822153T2 (de) | 2005-01-27 |
| PT986386E (pt) | 2004-07-30 |
| WO1998055118A2 (en) | 1998-12-10 |
| DE69822153D1 (de) | 2004-04-08 |
| WO1998055118A3 (en) | 1999-04-15 |
| ATE260655T1 (de) | 2004-03-15 |
| EP0986386A2 (en) | 2000-03-22 |
| EP0986386B1 (en) | 2004-03-03 |
| DK0986386T3 (da) | 2004-07-12 |
| AU8625598A (en) | 1998-12-21 |
| US6323230B1 (en) | 2001-11-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |