IT1264860B1 - Derivati di acidi cis- e trans-2(((2-(isdrossiammino)-2-ossoetil)- alchilammino)carbonil)cicloesancarbossilici - Google Patents
Derivati di acidi cis- e trans-2(((2-(isdrossiammino)-2-ossoetil)- alchilammino)carbonil)cicloesancarbossiliciInfo
- Publication number
- IT1264860B1 IT1264860B1 IT93MI001329A ITMI931329A IT1264860B1 IT 1264860 B1 IT1264860 B1 IT 1264860B1 IT 93MI001329 A IT93MI001329 A IT 93MI001329A IT MI931329 A ITMI931329 A IT MI931329A IT 1264860 B1 IT1264860 B1 IT 1264860B1
- Authority
- IT
- Italy
- Prior art keywords
- hydroxyamino
- oxoethyl
- alkylamino
- cis
- trans
- Prior art date
Links
- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical class [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 title 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 150000005378 cyclohexanecarboxylic acids Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT93MI001329A IT1264860B1 (it) | 1993-06-21 | 1993-06-21 | Derivati di acidi cis- e trans-2(((2-(isdrossiammino)-2-ossoetil)- alchilammino)carbonil)cicloesancarbossilici |
| FR9407523A FR2706897B1 (enrdf_load_stackoverflow) | 1993-06-21 | 1994-06-20 | |
| GB9412367A GB2279345A (en) | 1993-06-21 | 1994-06-20 | Cyclohexanecarboxylic acid derivatives |
| DE4421515A DE4421515A1 (de) | 1993-06-21 | 1994-06-20 | Cis- und trans-2-[[[2-(Hydroxyamino)-2-oxoethyl] -alkylamino]-carbonyl]-cyclohexancarbonsäure-Derivate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT93MI001329A IT1264860B1 (it) | 1993-06-21 | 1993-06-21 | Derivati di acidi cis- e trans-2(((2-(isdrossiammino)-2-ossoetil)- alchilammino)carbonil)cicloesancarbossilici |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI931329A0 ITMI931329A0 (it) | 1993-06-21 |
| ITMI931329A1 ITMI931329A1 (it) | 1994-12-21 |
| IT1264860B1 true IT1264860B1 (it) | 1996-10-17 |
Family
ID=11366439
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT93MI001329A IT1264860B1 (it) | 1993-06-21 | 1993-06-21 | Derivati di acidi cis- e trans-2(((2-(isdrossiammino)-2-ossoetil)- alchilammino)carbonil)cicloesancarbossilici |
Country Status (4)
| Country | Link |
|---|---|
| DE (1) | DE4421515A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2706897B1 (enrdf_load_stackoverflow) |
| GB (1) | GB2279345A (enrdf_load_stackoverflow) |
| IT (1) | IT1264860B1 (enrdf_load_stackoverflow) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5639746A (en) * | 1994-12-29 | 1997-06-17 | The Procter & Gamble Company | Hydroxamic acid-containing inhibitors of matrix metalloproteases |
| GB0509223D0 (en) * | 2005-05-05 | 2005-06-15 | Chroma Therapeutics Ltd | Enzyme inhibitors |
| JP7197880B2 (ja) * | 2017-10-19 | 2022-12-28 | 学校法人 名城大学 | エステル化剤及びその利用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1224627B (it) * | 1988-04-12 | 1990-10-04 | Guidotti & C Spa Labor | Ammidi di acidi ciclometilen_1,2_dicarbossilici adattivita' terapeutica, procedimenti per la loro preparazione e composizioni farmaceutiche che le contengono. |
| IT1252708B (it) * | 1991-12-23 | 1995-06-26 | Guidotti & C Spa Labor | Sali stabili dell'acido (+)-(1r,2s)-2((n-(2-idrossilammino-2-ossoetil)-n-metilammino)carbonil)cicloesan-1-carbossilico,ad attivita' ace inibitrice, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono. |
-
1993
- 1993-06-21 IT IT93MI001329A patent/IT1264860B1/it active IP Right Grant
-
1994
- 1994-06-20 GB GB9412367A patent/GB2279345A/en not_active Withdrawn
- 1994-06-20 FR FR9407523A patent/FR2706897B1/fr not_active Expired - Fee Related
- 1994-06-20 DE DE4421515A patent/DE4421515A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| DE4421515A1 (de) | 1994-12-22 |
| FR2706897A1 (enrdf_load_stackoverflow) | 1994-12-30 |
| FR2706897B1 (enrdf_load_stackoverflow) | 1996-01-26 |
| ITMI931329A1 (it) | 1994-12-21 |
| GB2279345A (en) | 1995-01-04 |
| GB9412367D0 (en) | 1994-08-10 |
| ITMI931329A0 (it) | 1993-06-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ITMI991860A0 (it) | Derivati di acidi 2-ammino-biciclo(3.1.0)-esan-2,6-bicarbossilici e pr ocedimento per la loro preparazione | |
| BR9611758A (pt) | Aril e heteroaril amidas de tetraidronaftaleno cromano tiocromano e ácidos 1,2,3,4-tetraidroquinolina carboxílicos tendo atividade biológica semelhante a retinóide | |
| TNSN94079A1 (fr) | Une nouvelle forme de compose | |
| AU1430895A (en) | (4-(1,2-epoxycyclohexanyl) but-3-EN-1-ynyl) aromatic and heteroaromatic acids and derivatives having retinoid-like biological activity | |
| CA2178632A1 (en) | Pharmaceutical compositions containing hiv protease inhibitors | |
| GEP20012414B (en) | Semicarbazones Having CNS Activity and Pharmaceutical Preparations Containing the Same | |
| UA39172C2 (uk) | Похідні 2-(2,6-дигалофеніламіно) фенілоцтової кислоти і спосіб їх одержання | |
| RU95106823A (ru) | Сукциноиламиногидроксиэтиламиносульфонамиды, фармацевтическая композиция, способ ингибирования ретровирусной протеазы, способ лечения ретровирусной инфекции способ лечения спида | |
| DE69608767D1 (de) | Neue stabile galenische formulierungen, die eine säurelabile benzimidazolverbindung enthalten, und herstellungsverfahren | |
| AU3853395A (en) | Preparation of hollow microcapsules | |
| WO1995021154A3 (de) | Phenylessigsäurederivate, verfahren und zwischenprodukte zu ihrer herstellung und sie enthaltende mittel | |
| ATE219940T1 (de) | Arzneimittel enthaltende cyclosporinderivate | |
| AU8866198A (en) | Method for preparing vesicular nanocapsules | |
| EP0532705A1 (en) | Quinolinyl-benzoheterobicyclic derivatives as antagonists of leukotriene d 4? | |
| AU2002250914A1 (en) | Method for producing an active ingredient concentrate, and an active ingredient concentrate | |
| IT1264860B1 (it) | Derivati di acidi cis- e trans-2(((2-(isdrossiammino)-2-ossoetil)- alchilammino)carbonil)cicloesancarbossilici | |
| FR2609395B1 (fr) | Utilisation de bases xanthiques comme principe actif d'une composition pharmaceutique, notamment dermatologique, ou cosmetique, composition notamment utile comme matiere de base pour la preparation de composition pharmaceutique ou cosmetique et composition pharmaceutique ou cosmetique ainsi preparee | |
| IT8920169A0 (it) | Derivati di acidi biliari, loro preparazione e composizioni farmaceutiche che li contengono. | |
| AU4434189A (en) | An anti-human immunodeficiency virus composition | |
| HUT50844A (en) | Process for producing new 2'-halogen methylidene, 2'-ethenylidene and 2'-ethinyladenosine derivatives and pharmaceutical compositions comprising same as active ingredient | |
| FR2763944B1 (fr) | Nouveaux derives de coumarines, leurs procedes de preparation et leur application comme medicaments en tant qu'inhibiteurs de proteases | |
| RU94000064A (ru) | Новые 2-циано-3-гидроксипропенамиды, метод их получения и содержащие их фармацевтические композиции | |
| ATE284215T1 (de) | Transdermale systeme enthaltend zwei wirkstoffe in getrennten abteilungen, ihre herstellungsverfahren und verwendung als arzneimittel | |
| AU7575796A (en) | Novel imidazole n-benzyldioxol derivatives, method for preparing same, resulting intermediates, pharmaceutical compositions and use of said derivatives as endothelin antagonists | |
| CA2136607A1 (en) | Pharmaceutical Powder Composition Containing Non-Ionic Cellulose Ether Derivative and a Chitin-Derived Polymer |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970626 |