IT1244361B - Processo per la preparazione dell'acido 5-(2,4-difluorofenil)- salicilico - Google Patents
Processo per la preparazione dell'acido 5-(2,4-difluorofenil)- salicilicoInfo
- Publication number
- IT1244361B IT1244361B ITMI910027A ITMI910027A IT1244361B IT 1244361 B IT1244361 B IT 1244361B IT MI910027 A ITMI910027 A IT MI910027A IT MI910027 A ITMI910027 A IT MI910027A IT 1244361 B IT1244361 B IT 1244361B
- Authority
- IT
- Italy
- Prior art keywords
- difluorophenyl
- preparation
- salicylic acid
- difluorohalobenzene
- reaction
- Prior art date
Links
- HUPFGZXOMWLGNK-UHFFFAOYSA-N diflunisal Chemical compound C1=C(O)C(C(=O)O)=CC(C=2C(=CC(F)=CC=2)F)=C1 HUPFGZXOMWLGNK-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000003054 catalyst Substances 0.000 abstract 1
- 125000002524 organometallic group Chemical group 0.000 abstract 1
- 230000007704 transition Effects 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Viene descritto un processo per la preparazione dell'acido 5-(2, 4-difluorofenil)-salicilico che comprende la reazione di un derivato metallorganico con un 2, 4-difluoroalobenzene in presenza di catalizzatori a base di metalli di transizione.
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI910027A IT1244361B (it) | 1991-01-08 | 1991-01-08 | Processo per la preparazione dell'acido 5-(2,4-difluorofenil)- salicilico |
IL100353A IL100353A (en) | 1991-01-08 | 1991-12-12 | Preparation of 5-(2, 4-difluorophenyl)-salicylic acid and novel 2,4-difluorophenyl-boronic acid derivatives being intermediates therefor |
US07/813,661 US5312975A (en) | 1991-01-08 | 1991-12-27 | Process for the preparation of 5-(2,4-difluorophenyl)-salicylic acid |
JP03361474A JP3106259B2 (ja) | 1991-01-08 | 1991-12-27 | 5−(2,4−ジフルオロフェニル)−サリチル酸の製造方法 |
CA002058646A CA2058646C (en) | 1991-01-08 | 1991-12-31 | Process for the preparation of 5-(2,4-difluorophenyl)-salicylic acid |
AT91121785T ATE131149T1 (de) | 1991-01-08 | 1992-01-01 | Verfahren zur herstellung von 5-(2,4- difluorphenyl)-salizylsäure. |
DK91121785.9T DK0494419T3 (da) | 1991-01-08 | 1992-01-01 | Fremgangsmåde til fremstilling af 5-(2,4-difluorphenyl)-salicylsyre |
DE69206423T DE69206423T2 (de) | 1991-01-08 | 1992-01-01 | Verfahren zur Herstellung von 5-(2,4-Difluorphenyl)-Salizylsäure. |
EP91121785A EP0494419B1 (en) | 1991-01-08 | 1992-01-01 | Process for the preparation of 5-(2,4-difluorophenyl)-salicylic acid |
ES91121785T ES2081417T3 (es) | 1991-01-08 | 1992-01-01 | Procedimiento para la preparacion de acido 5-(2,4-difluorofenil)-salicilico. |
FI920069A FI103788B (fi) | 1991-01-08 | 1992-01-08 | Menetelmä 5-(2,4-difluorifenyyli)salisyylihapon valmistamiseksi |
US08/174,316 US5412143A (en) | 1991-01-08 | 1993-12-30 | Process for the preparation of 5-(2,4-difluorophenyl)-salicylic acid |
GR950403706T GR3018569T3 (en) | 1991-01-08 | 1995-12-29 | Process for the preparation of 5-(2,4-difluorophenyl)-salicylic acid. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI910027A IT1244361B (it) | 1991-01-08 | 1991-01-08 | Processo per la preparazione dell'acido 5-(2,4-difluorofenil)- salicilico |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI910027A0 ITMI910027A0 (it) | 1991-01-08 |
ITMI910027A1 ITMI910027A1 (it) | 1992-07-08 |
IT1244361B true IT1244361B (it) | 1994-07-08 |
Family
ID=11358035
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI910027A IT1244361B (it) | 1991-01-08 | 1991-01-08 | Processo per la preparazione dell'acido 5-(2,4-difluorofenil)- salicilico |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1244361B (it) |
-
1991
- 1991-01-08 IT ITMI910027A patent/IT1244361B/it active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
ITMI910027A0 (it) | 1991-01-08 |
ITMI910027A1 (it) | 1992-07-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19941228 |