IT1241128B - PROCEDURE FOR THE PREPARATION OF KINAZOLINIC DERIVATIVES - Google Patents

PROCEDURE FOR THE PREPARATION OF KINAZOLINIC DERIVATIVES

Info

Publication number
IT1241128B
IT1241128B IT20092A IT2009290A IT1241128B IT 1241128 B IT1241128 B IT 1241128B IT 20092 A IT20092 A IT 20092A IT 2009290 A IT2009290 A IT 2009290A IT 1241128 B IT1241128 B IT 1241128B
Authority
IT
Italy
Prior art keywords
kinazolinic
derivatives
procedure
preparation
kinazolinic derivatives
Prior art date
Application number
IT20092A
Other languages
Italian (it)
Other versions
IT9020092A1 (en
IT9020092A0 (en
Inventor
Frigyes Gorgenyi
Margit Csorgo
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU193089A external-priority patent/HU203333B/en
Priority claimed from HU193189A external-priority patent/HU203342B/en
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of IT9020092A0 publication Critical patent/IT9020092A0/en
Publication of IT9020092A1 publication Critical patent/IT9020092A1/en
Application granted granted Critical
Publication of IT1241128B publication Critical patent/IT1241128B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IT20092A 1989-04-21 1990-04-20 PROCEDURE FOR THE PREPARATION OF KINAZOLINIC DERIVATIVES IT1241128B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU193089A HU203333B (en) 1989-04-21 1989-04-21 Process for producing n-cyano-carboxamidine derivatives
HU193189A HU203342B (en) 1989-04-21 1989-04-21 Process for producing quinazoline deivatives

Publications (3)

Publication Number Publication Date
IT9020092A0 IT9020092A0 (en) 1990-04-20
IT9020092A1 IT9020092A1 (en) 1991-10-20
IT1241128B true IT1241128B (en) 1993-12-29

Family

ID=26317437

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20092A IT1241128B (en) 1989-04-21 1990-04-20 PROCEDURE FOR THE PREPARATION OF KINAZOLINIC DERIVATIVES

Country Status (16)

Country Link
JP (1) JPH02292282A (en)
KR (1) KR900016194A (en)
AT (1) AT398075B (en)
BG (1) BG91821A (en)
CA (2) CA2028953A1 (en)
CH (1) CH681300A5 (en)
DK (1) DK99090A (en)
ES (1) ES2019826A6 (en)
FI (1) FI902002A0 (en)
GB (1) GB2231571B (en)
GR (1) GR900100294A (en)
IT (1) IT1241128B (en)
PL (1) PL162976B1 (en)
RU (1) RU1838309C (en)
SE (1) SE9001402L (en)
YU (1) YU70890A (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2077252C (en) * 1992-08-31 2001-04-10 Khashayar Karimian Methods of making ureas and guanidines, and intermediates therefor
ES2096518B1 (en) * 1994-03-28 1997-12-01 Grupo Farmaceutico Almirall S NEW RINGS.
WO2008015525A2 (en) * 2006-07-31 2008-02-07 Orchid Chemicals & Pharmaceuticals Limited An improved process for the preparation of alfuzosin hydrochloride
US20100174073A1 (en) 2007-05-04 2010-07-08 Actavis Group Ptc Ehf Process for the preparation of alfuzosin and salts thereof
JP2010535185A (en) 2007-08-02 2010-11-18 シプラ・リミテッド Method for producing alfuzosin hydrochloride

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4044135A (en) * 1975-10-14 1977-08-23 Abbott Laboratories Antihypertensive agents
US4026894A (en) * 1975-10-14 1977-05-31 Abbott Laboratories Antihypertensive agents
GB1591490A (en) * 1977-08-04 1981-06-24 Abbott Lab 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride dihydrate
US4138561A (en) * 1977-09-30 1979-02-06 Bristol-Myers Company Cyanocarboxamidines and quinazoline process
FI56836C (en) * 1977-10-25 1980-04-10 Fermion Oy 4-SUBSTITUTES OF PIPERAZIN-1- (N-ARYL-N'-CYANO) -CARBOXIMIDAMIDER BUTTER OF THE BREAST PREPARATION WITH PHARMACOLOGICAL PROPERTIES 6,7-DIMETOXY-ELLER 6,7,8-TRIMETOXY-2-AMINO -SUBSTITUERADE-Piperazine-1-YL) -KINAZOLINER
FI57751C (en) * 1977-10-25 1980-10-10 Fermion Oy PROCEDURE FOR THE FRAMSTATION OF 6,7-DIMETOXY-ELLER 6,7,8-TRIMETOXY-4-AMINO-2- (4-SUBSTITUTES-PIPERAZIN-1-YL) -KINAZOLINE WITH BLODTRYCKSSAKANDE NETKAN
FR2421888A1 (en) * 1978-02-06 1979-11-02 Synthelabo ALKYLENE DIAMINE AMIDES AND THEIR APPLICATION IN THERAPEUTICS
FI59800C (en) * 1979-01-10 1981-10-12 Fermion Oy PROCEDURE FOR THE FRAMSTATION OF 6,7-DIMETOXY-4-AMINO-2- (4- (FURO-2-YL) -PIPERASIN-1-YL) -QUINAZOLINE
FI67699C (en) * 1979-01-31 1985-05-10 Orion Yhtymae Oy PROCEDURE FOR THE FRAMSTATION OF AV 6,7-DIMETOXY-4-AMINO-2- (4- (2-FUROYL) -1-PIPERAZINYL) QUINAZOLINE HYDROCHLORIDE WITH BLODTRYCKSSAENKANDE VERKAN
DE3375395D1 (en) * 1983-11-22 1988-02-25 Heumann Ludwig & Co Gmbh Process for the preparation of 4-amino-6,7-dimethoxy-2-(4-(furoyl-2)-piperazin-1-yl)-quinazoline and its physiologically acceptable salt

Also Published As

Publication number Publication date
KR900016194A (en) 1990-11-12
BG91821A (en) 1993-12-24
GB9008941D0 (en) 1990-06-20
PL284860A1 (en) 1991-03-11
IT9020092A1 (en) 1991-10-20
DK99090A (en) 1990-10-22
ES2019826A6 (en) 1991-07-01
IT9020092A0 (en) 1990-04-20
CA2028953A1 (en) 1990-10-22
JPH02292282A (en) 1990-12-03
GR900100294A (en) 1991-09-27
GB2231571B (en) 1992-09-16
CA2015066A1 (en) 1990-10-21
GB2231571A (en) 1990-11-21
AT398075B (en) 1994-09-26
DK99090D0 (en) 1990-04-20
FI902002A0 (en) 1990-04-20
CH681300A5 (en) 1993-02-26
YU70890A (en) 1992-05-28
SE9001402D0 (en) 1990-04-20
ATA93190A (en) 1994-01-15
PL162976B1 (en) 1994-01-31
SE9001402L (en) 1990-10-22
RU1838309C (en) 1993-08-30

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19940428