GR900100294A - Process for the preparation of quinazoline derivatives - Google Patents

Process for the preparation of quinazoline derivatives

Info

Publication number
GR900100294A
GR900100294A GR900100294A GR900100294A GR900100294A GR 900100294 A GR900100294 A GR 900100294A GR 900100294 A GR900100294 A GR 900100294A GR 900100294 A GR900100294 A GR 900100294A GR 900100294 A GR900100294 A GR 900100294A
Authority
GR
Greece
Prior art keywords
preparation
quinazoline derivatives
quinazoline
derivatives
general formula
Prior art date
Application number
GR900100294A
Other languages
Greek (el)
Inventor
Margit Csorgo
Marton Fekete
Frigyes Gorgenyi
Laszlo Pongo
Jozsef Reiter
Ilona Sztuhar
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU193089A external-priority patent/HU203333B/en
Priority claimed from HU193189A external-priority patent/HU203342B/en
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of GR900100294A publication Critical patent/GR900100294A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Η εφεύρεσις αναφέρεται εις μέθοδον δια την παρασκευήν παραγώγων κιναζολίνης του γενικού Τύπου ΙωThe invention relates to a process for the preparation of quinazoline derivatives of the general formula Io

GR900100294A 1989-04-21 1990-04-19 Process for the preparation of quinazoline derivatives GR900100294A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU193089A HU203333B (en) 1989-04-21 1989-04-21 Process for producing n-cyano-carboxamidine derivatives
HU193189A HU203342B (en) 1989-04-21 1989-04-21 Process for producing quinazoline deivatives

Publications (1)

Publication Number Publication Date
GR900100294A true GR900100294A (en) 1991-09-27

Family

ID=26317437

Family Applications (1)

Application Number Title Priority Date Filing Date
GR900100294A GR900100294A (en) 1989-04-21 1990-04-19 Process for the preparation of quinazoline derivatives

Country Status (16)

Country Link
JP (1) JPH02292282A (en)
KR (1) KR900016194A (en)
AT (1) AT398075B (en)
BG (1) BG91821A (en)
CA (2) CA2028953A1 (en)
CH (1) CH681300A5 (en)
DK (1) DK99090A (en)
ES (1) ES2019826A6 (en)
FI (1) FI902002A0 (en)
GB (1) GB2231571B (en)
GR (1) GR900100294A (en)
IT (1) IT1241128B (en)
PL (1) PL162976B1 (en)
RU (1) RU1838309C (en)
SE (1) SE9001402L (en)
YU (1) YU70890A (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2077252C (en) * 1992-08-31 2001-04-10 Khashayar Karimian Methods of making ureas and guanidines, and intermediates therefor
ES2096518B1 (en) * 1994-03-28 1997-12-01 Grupo Farmaceutico Almirall S NEW RINGS.
WO2008015525A2 (en) * 2006-07-31 2008-02-07 Orchid Chemicals & Pharmaceuticals Limited An improved process for the preparation of alfuzosin hydrochloride
US20100174073A1 (en) 2007-05-04 2010-07-08 Actavis Group Ptc Ehf Process for the preparation of alfuzosin and salts thereof
JP2010535185A (en) 2007-08-02 2010-11-18 シプラ・リミテッド Method for producing alfuzosin hydrochloride

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1979000166A1 (en) * 1977-09-30 1979-04-05 Bristol Myers Co Cyanocarboxamidines and quinazoline process
NL7804135A (en) * 1977-10-25 1979-04-27 Fermion Oy PROCESS FOR PREPARING CHINAZOLINES.
NL7902400A (en) * 1979-01-10 1980-07-14 Fermion Oy PROCESS FOR PREPARING CHINAZOLINES.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4044135A (en) * 1975-10-14 1977-08-23 Abbott Laboratories Antihypertensive agents
US4026894A (en) * 1975-10-14 1977-05-31 Abbott Laboratories Antihypertensive agents
GB1591490A (en) * 1977-08-04 1981-06-24 Abbott Lab 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride dihydrate
FI56836C (en) * 1977-10-25 1980-04-10 Fermion Oy 4-SUBSTITUTES OF PIPERAZIN-1- (N-ARYL-N'-CYANO) -CARBOXIMIDAMIDER BUTTER OF THE BREAST PREPARATION WITH PHARMACOLOGICAL PROPERTIES 6,7-DIMETOXY-ELLER 6,7,8-TRIMETOXY-2-AMINO -SUBSTITUERADE-Piperazine-1-YL) -KINAZOLINER
FR2421888A1 (en) * 1978-02-06 1979-11-02 Synthelabo ALKYLENE DIAMINE AMIDES AND THEIR APPLICATION IN THERAPEUTICS
FI67699C (en) * 1979-01-31 1985-05-10 Orion Yhtymae Oy PROCEDURE FOR THE FRAMSTATION OF AV 6,7-DIMETOXY-4-AMINO-2- (4- (2-FUROYL) -1-PIPERAZINYL) QUINAZOLINE HYDROCHLORIDE WITH BLODTRYCKSSAENKANDE VERKAN
DE3375395D1 (en) * 1983-11-22 1988-02-25 Heumann Ludwig & Co Gmbh Process for the preparation of 4-amino-6,7-dimethoxy-2-(4-(furoyl-2)-piperazin-1-yl)-quinazoline and its physiologically acceptable salt

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1979000166A1 (en) * 1977-09-30 1979-04-05 Bristol Myers Co Cyanocarboxamidines and quinazoline process
NL7804135A (en) * 1977-10-25 1979-04-27 Fermion Oy PROCESS FOR PREPARING CHINAZOLINES.
NL7902400A (en) * 1979-01-10 1980-07-14 Fermion Oy PROCESS FOR PREPARING CHINAZOLINES.

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CLAIMS SEARCHED: ALL *

Also Published As

Publication number Publication date
KR900016194A (en) 1990-11-12
BG91821A (en) 1993-12-24
GB9008941D0 (en) 1990-06-20
PL284860A1 (en) 1991-03-11
IT9020092A1 (en) 1991-10-20
DK99090A (en) 1990-10-22
ES2019826A6 (en) 1991-07-01
IT9020092A0 (en) 1990-04-20
CA2028953A1 (en) 1990-10-22
JPH02292282A (en) 1990-12-03
GB2231571B (en) 1992-09-16
CA2015066A1 (en) 1990-10-21
GB2231571A (en) 1990-11-21
AT398075B (en) 1994-09-26
DK99090D0 (en) 1990-04-20
FI902002A0 (en) 1990-04-20
CH681300A5 (en) 1993-02-26
YU70890A (en) 1992-05-28
SE9001402D0 (en) 1990-04-20
ATA93190A (en) 1994-01-15
IT1241128B (en) 1993-12-29
PL162976B1 (en) 1994-01-31
SE9001402L (en) 1990-10-22
RU1838309C (en) 1993-08-30

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