IT1235336B - Sale di trometammina di i-metil-beta-osso-alfa-(fenilcarbammoil)-2- pirrolpropionitrile, composizione che lo contiene e procedimento di preparazione ed applicazione - Google Patents
Sale di trometammina di i-metil-beta-osso-alfa-(fenilcarbammoil)-2- pirrolpropionitrile, composizione che lo contiene e procedimento di preparazione ed applicazioneInfo
- Publication number
- IT1235336B IT1235336B IT8848657A IT4865788A IT1235336B IT 1235336 B IT1235336 B IT 1235336B IT 8848657 A IT8848657 A IT 8848657A IT 4865788 A IT4865788 A IT 4865788A IT 1235336 B IT1235336 B IT 1235336B
- Authority
- IT
- Italy
- Prior art keywords
- thometamine
- pyrolpropionitrile
- fenylcarbammoil
- bone
- beta
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1987/003413 WO1989005798A1 (en) | 1987-12-18 | 1987-12-18 | TROMETHAMINE SALT OF 1-METHYL-beta-OXO-alpha-(PHENYLCARBAMOYL)-2-PYRROLEPROPIONITRILE |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8848657A0 IT8848657A0 (it) | 1988-12-15 |
IT1235336B true IT1235336B (it) | 1992-06-30 |
Family
ID=22202723
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT8848657A IT1235336B (it) | 1987-12-18 | 1988-12-15 | Sale di trometammina di i-metil-beta-osso-alfa-(fenilcarbammoil)-2- pirrolpropionitrile, composizione che lo contiene e procedimento di preparazione ed applicazione |
Country Status (22)
Country | Link |
---|---|
US (1) | US4977181A (it) |
JP (1) | JPH02502534A (it) |
KR (1) | KR890009868A (it) |
AT (1) | AT390437B (it) |
AU (1) | AU3596889A (it) |
DD (1) | DD283375A5 (it) |
DE (1) | DE3842250A1 (it) |
DK (1) | DK704188A (it) |
ES (1) | ES2012578A6 (it) |
FI (1) | FI885828A (it) |
FR (1) | FR2624856A1 (it) |
GB (1) | GB2211187A (it) |
HU (1) | HU199788B (it) |
IL (1) | IL88654A0 (it) |
IT (1) | IT1235336B (it) |
LU (1) | LU87406A1 (it) |
NL (1) | NL8803092A (it) |
NO (1) | NO885576L (it) |
PT (1) | PT88104A (it) |
WO (1) | WO1989005798A1 (it) |
YU (1) | YU227788A (it) |
ZA (1) | ZA889355B (it) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH02502534A (ja) * | 1987-12-18 | 1990-08-16 | チバ‐ガイギー アクチェンゲゼルシャフト | 1‐メチル‐β‐オキソ‐α‐(フェニルカルバモイル)‐2‐ピロールプロピオニトリルのトロメタミン塩 |
ES2058024B1 (es) * | 1992-11-10 | 1995-05-01 | Menarini Lab | Nuevo derivado arilpropionico, procedimiento de fabricacion del mismo y su utilizacion como analgesico. |
US5431717A (en) * | 1993-12-03 | 1995-07-11 | Geobiotics, Inc. | Method for rendering refractory sulfide ores more susceptible to biooxidation |
US7008979B2 (en) | 2002-04-30 | 2006-03-07 | Hydromer, Inc. | Coating composition for multiple hydrophilic applications |
KR100576332B1 (ko) | 2004-07-16 | 2006-05-03 | 강승우 | 신규한 글라이세리드 유도체 및 이를 포함하는 통증완화용조성물 |
EP2854768B1 (en) | 2012-05-30 | 2017-03-22 | Fresenius Kabi Oncology Limited | Pharmaceutical compositions of pemetrexed |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU4028772A (en) * | 1971-04-02 | 1973-09-27 | Merck & Co., Inc | Chemical processes |
GB1398072A (en) * | 1971-06-14 | 1975-06-18 | May & Baker Ltd | Cyclopentane derivatives |
US4089969A (en) * | 1976-07-14 | 1978-05-16 | Syntex (U.S.A.) Inc. | 5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof |
DD151307A5 (de) * | 1979-06-11 | 1981-10-14 | Ciba Geigy Ag | Verfahren zur herstellung von alphacarbamoyl-pyrrol-propionitrilen |
US4256759A (en) * | 1979-06-11 | 1981-03-17 | Ciba-Geigy Corporation | Alphacarbamoyl-pyrrolpropionitriles |
HU185926B (en) * | 1979-09-27 | 1985-04-28 | Agostne Kahan | Process for preparing water soluble derivatives of non-steroid antiinflammatory compositions and pharmaceutical compositins containing such derivatives |
US4644010A (en) * | 1982-09-28 | 1987-02-17 | Ciba-Geigy Corporation | Certain β-oxo-α-carbamoylpyrrolepropionitriles |
JPH02502534A (ja) * | 1987-12-18 | 1990-08-16 | チバ‐ガイギー アクチェンゲゼルシャフト | 1‐メチル‐β‐オキソ‐α‐(フェニルカルバモイル)‐2‐ピロールプロピオニトリルのトロメタミン塩 |
-
1987
- 1987-12-18 JP JP63500815A patent/JPH02502534A/ja active Pending
- 1987-12-18 US US07/424,297 patent/US4977181A/en not_active Expired - Fee Related
- 1987-12-18 WO PCT/US1987/003413 patent/WO1989005798A1/en active Application Filing
-
1988
- 1988-07-26 PT PT88104A patent/PT88104A/pt not_active Application Discontinuation
- 1988-12-11 IL IL88654A patent/IL88654A0/xx unknown
- 1988-12-14 LU LU87406A patent/LU87406A1/de unknown
- 1988-12-14 GB GB8829136A patent/GB2211187A/en not_active Withdrawn
- 1988-12-14 ZA ZA889355A patent/ZA889355B/xx unknown
- 1988-12-15 IT IT8848657A patent/IT1235336B/it active
- 1988-12-15 DE DE3842250A patent/DE3842250A1/de not_active Withdrawn
- 1988-12-15 NO NO88885576A patent/NO885576L/no unknown
- 1988-12-16 KR KR1019880016763A patent/KR890009868A/ko not_active Application Discontinuation
- 1988-12-16 DD DD88323311A patent/DD283375A5/de not_active IP Right Cessation
- 1988-12-16 ES ES888803830A patent/ES2012578A6/es not_active Expired - Lifetime
- 1988-12-16 YU YU02277/88A patent/YU227788A/xx unknown
- 1988-12-16 FR FR8816638A patent/FR2624856A1/fr not_active Withdrawn
- 1988-12-16 NL NL8803092A patent/NL8803092A/nl not_active Application Discontinuation
- 1988-12-16 HU HU886477A patent/HU199788B/hu not_active IP Right Cessation
- 1988-12-16 DK DK704188A patent/DK704188A/da not_active Application Discontinuation
- 1988-12-16 FI FI885828A patent/FI885828A/fi not_active Application Discontinuation
- 1988-12-16 AT AT0307488A patent/AT390437B/de not_active IP Right Cessation
-
1989
- 1989-03-21 AU AU35968/89A patent/AU3596889A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
FI885828A (fi) | 1989-06-19 |
LU87406A1 (de) | 1990-02-28 |
FI885828A0 (fi) | 1988-12-16 |
IL88654A0 (en) | 1989-07-31 |
DE3842250A1 (de) | 1989-06-29 |
PT88104A (pt) | 1989-09-14 |
AT390437B (de) | 1990-05-10 |
WO1989005798A1 (en) | 1989-06-29 |
NO885576D0 (no) | 1988-12-15 |
JPH02502534A (ja) | 1990-08-16 |
YU227788A (en) | 1990-08-31 |
DK704188D0 (da) | 1988-12-16 |
DD283375A5 (de) | 1990-10-10 |
AU3596889A (en) | 1990-01-11 |
ES2012578A6 (es) | 1990-04-01 |
HUT48582A (en) | 1989-06-28 |
GB2211187A (en) | 1989-06-28 |
DK704188A (da) | 1989-06-19 |
US4977181A (en) | 1990-12-11 |
KR890009868A (ko) | 1989-08-04 |
FR2624856A1 (en) | 1989-06-23 |
HU199788B (en) | 1990-03-28 |
NL8803092A (nl) | 1989-07-17 |
ATA307488A (de) | 1989-10-15 |
GB8829136D0 (en) | 1989-01-25 |
IT8848657A0 (it) | 1988-12-15 |
NO885576L (no) | 1989-06-19 |
ZA889355B (en) | 1989-10-25 |
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