IT1223537B - Amino antracenedioni bis platino complessi utili come agenti antitumorali - Google Patents
Amino antracenedioni bis platino complessi utili come agenti antitumoraliInfo
- Publication number
- IT1223537B IT1223537B IT23094/87A IT2309487A IT1223537B IT 1223537 B IT1223537 B IT 1223537B IT 23094/87 A IT23094/87 A IT 23094/87A IT 2309487 A IT2309487 A IT 2309487A IT 1223537 B IT1223537 B IT 1223537B
- Authority
- IT
- Italy
- Prior art keywords
- ch3soch3
- ch2ch2o
- alkoxy
- alkyl
- platinum complexes
- Prior art date
Links
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 title abstract 4
- 150000003057 platinum Chemical class 0.000 title abstract 2
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 2
- 125000004122 cyclic group Chemical group 0.000 abstract 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 125000004202 aminomethyl group Chemical group [H]N([H])C([H])([H])* 0.000 abstract 1
- 150000001450 anions Chemical group 0.000 abstract 1
- LSOTZYUVGZKSHR-UHFFFAOYSA-N anthracene-1,4-dione Chemical compound C1=CC=C2C=C3C(=O)C=CC(=O)C3=CC2=C1 LSOTZYUVGZKSHR-UHFFFAOYSA-N 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 229940093499 ethyl acetate Drugs 0.000 abstract 1
- 235000019439 ethyl acetate Nutrition 0.000 abstract 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT23094/87A IT1223537B (it) | 1987-12-18 | 1987-12-18 | Amino antracenedioni bis platino complessi utili come agenti antitumorali |
| AU28175/89A AU2817589A (en) | 1987-12-18 | 1988-12-07 | Amino anthracenediones-bis platinum complexes, useful as antitumoral agents |
| PCT/EP1988/001110 WO1989005815A1 (en) | 1987-12-18 | 1988-12-07 | Amino anthracenediones-bis platinum complexes, useful as antitumoral agents |
| EP89900592A EP0396588A1 (en) | 1987-12-18 | 1988-12-07 | Amino anthracenediones-bis platinum complexes, useful as antitumoral agents |
| JP1500325A JPH03503046A (ja) | 1987-12-18 | 1988-12-07 | 抗腫瘍剤として有用なアミノアントラセンジオン‐ビス白金錯体 |
| US07/499,405 US5145848A (en) | 1987-12-18 | 1988-12-07 | Amino anthracenediones-bis platinum complexes, useful as antitumoral agents |
| CA000586002A CA1327355C (en) | 1987-12-18 | 1988-12-15 | Amino anthracenediones-bis platinum complexes, useful as antitumoral agents |
| ZA889413A ZA889413B (en) | 1987-12-18 | 1988-12-15 | Amino anthracenediones-bis platinum complexes,useful as antitumoral agents |
| DE88121072T DE3880991T2 (de) | 1987-12-18 | 1988-12-16 | Aminoanthracendion-bis-platinkomplexe, nützlich als Antitumor-Agenzien. |
| EP88121072A EP0320960B1 (en) | 1987-12-18 | 1988-12-16 | Amino anthracenediones-bis platinum complexes, useful as antitumoral agents |
| ES88121072T ES2056887T3 (es) | 1987-12-18 | 1988-12-16 | Complejos de amino-antracenodiona-bis-platino, utiles como agentes antitumorales. |
| AT88121072T ATE89284T1 (de) | 1987-12-18 | 1988-12-16 | Aminoanthracendion-bis-platinkomplexe, nuetzlich als antitumor-agenzien. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT23094/87A IT1223537B (it) | 1987-12-18 | 1987-12-18 | Amino antracenedioni bis platino complessi utili come agenti antitumorali |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8723094A0 IT8723094A0 (it) | 1987-12-18 |
| IT1223537B true IT1223537B (it) | 1990-09-19 |
Family
ID=11203721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT23094/87A IT1223537B (it) | 1987-12-18 | 1987-12-18 | Amino antracenedioni bis platino complessi utili come agenti antitumorali |
Country Status (2)
| Country | Link |
|---|---|
| IT (1) | IT1223537B (it) |
| ZA (1) | ZA889413B (it) |
-
1987
- 1987-12-18 IT IT23094/87A patent/IT1223537B/it active
-
1988
- 1988-12-15 ZA ZA889413A patent/ZA889413B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA889413B (en) | 1990-08-29 |
| IT8723094A0 (it) | 1987-12-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19931230 |