IT1218732B - Metodo per la produzione di un fattore di crescita per cellule di mammiferi e relativo fattore di crescita di linfociti cosi' ottenuto - Google Patents

Metodo per la produzione di un fattore di crescita per cellule di mammiferi e relativo fattore di crescita di linfociti cosi' ottenuto

Info

Publication number
IT1218732B
IT1218732B IT83481/83A IT8348183A IT1218732B IT 1218732 B IT1218732 B IT 1218732B IT 83481/83 A IT83481/83 A IT 83481/83A IT 8348183 A IT8348183 A IT 8348183A IT 1218732 B IT1218732 B IT 1218732B
Authority
IT
Italy
Prior art keywords
growth factor
production
mammalian cells
related lymphocyte
lymphocyte growth
Prior art date
Application number
IT83481/83A
Other languages
English (en)
Other versions
IT8383481A0 (it
Inventor
Harvey Ira Cantor
Gary Nabel
Original Assignee
Dana Farber Cancer Inst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dana Farber Cancer Inst Inc filed Critical Dana Farber Cancer Inst Inc
Publication of IT8383481A0 publication Critical patent/IT8383481A0/it
Application granted granted Critical
Publication of IT1218732B publication Critical patent/IT1218732B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6813—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin the drug being a peptidic cytokine, e.g. an interleukin or interferon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IT83481/83A 1982-10-20 1983-10-20 Metodo per la produzione di un fattore di crescita per cellule di mammiferi e relativo fattore di crescita di linfociti cosi' ottenuto IT1218732B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/435,510 US4613459A (en) 1982-10-20 1982-10-20 Lymphocyte growth factor

Publications (2)

Publication Number Publication Date
IT8383481A0 IT8383481A0 (it) 1983-10-20
IT1218732B true IT1218732B (it) 1990-04-19

Family

ID=23728694

Family Applications (1)

Application Number Title Priority Date Filing Date
IT83481/83A IT1218732B (it) 1982-10-20 1983-10-20 Metodo per la produzione di un fattore di crescita per cellule di mammiferi e relativo fattore di crescita di linfociti cosi' ottenuto

Country Status (7)

Country Link
US (1) US4613459A (it)
EP (1) EP0122936B1 (it)
DE (1) DE3381082D1 (it)
IE (1) IE56089B1 (it)
IL (1) IL69985A (it)
IT (1) IT1218732B (it)
WO (1) WO1984001504A1 (it)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5093479A (en) * 1981-04-17 1992-03-03 Shanksville Corp. N.V. Regulatory glycoprotein for immune response and the use, thereof in the production of t-cell growth factor
US5330896A (en) * 1983-02-24 1994-07-19 Billing Ronald J Monoclonal antibodies to an autocrine growth factor antigen that binds to activated lymphocytes and cancer cells
US4730036A (en) * 1984-01-03 1988-03-08 Sloan-Kettering Institute For Cancer Research Purifications of B-cell inducing factor (BIF) and B-cell growth factor (BGF)
US4849506A (en) * 1984-04-13 1989-07-18 Akzo N.V. Leukoregulin, an antitumor lymphokine, and its therapeutic uses
US5807996A (en) * 1985-11-19 1998-09-15 Schering Corporation Fused polypeptides comprising interleukin-4 polypeptide fragments
IL80678A (en) * 1985-11-19 1999-05-09 Schering Biotech Corp Human interleukin-4
US5017691A (en) * 1986-07-03 1991-05-21 Schering Corporation Mammalian interleukin-4
US5656266A (en) * 1985-11-19 1997-08-12 Schering Corporation Method of using interleukin-4
JPS63126897A (ja) * 1986-05-02 1988-05-30 Yoshitomi Pharmaceut Ind Ltd 免疫抑制因子
US4997537A (en) * 1986-10-21 1991-03-05 Northeastern University High performance microcapillary gel electrophoresis
US5665216A (en) * 1986-10-21 1997-09-09 Northeastern University Capillary column for high performance electrophoretic separation and detection of SDS proteins and system and using the same
JPH03503840A (ja) * 1988-01-15 1991-08-29 セントコアー，インコーポレーテッド 異種連結抗体およびその治療的使用
CA2048078A1 (en) * 1990-11-15 1992-05-16 Wolfgang A. Wrasidlo Chemical modification of antibodies for creation of immunoconjugates
JPH08501281A (ja) * 1992-06-05 1996-02-13 シナジェン，インコーポレイテッド Ｔ細胞膜誘発因子
FI98493C (fi) * 1994-06-10 1997-07-10 Olavi Kajander Kasvutekijävalmiste, menetelmä sen valmistamiseksi ja käyttämiseksi ja sitä sisältävä elatusaine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL47372A (en) * 1975-05-27 1979-10-31 Yeda Res & Dev Fab'dimers bound to daunomycin or adriamycin,their preparation and pharmaceutical compositions containing same
US4323561A (en) * 1977-09-06 1982-04-06 Temple University Of The Commonwealth System Of Higher Education Process of enhancing immmunogenic response in mammals by the administration of synthetic glycolipid adjuvants
US4172124A (en) * 1978-04-28 1979-10-23 The Wistar Institute Method of producing tumor antibodies
US4271145A (en) * 1979-10-22 1981-06-02 The Massachusetts General Hospital Process for producing antibodies to hepatitis virus and cell lines therefor
EP0049611B2 (en) * 1980-10-02 1993-12-08 Hooper Trading Co. N.V. A T-cell growth factor, and a process of producing the same
US4438032A (en) * 1981-01-30 1984-03-20 The Regents Of The University Of California Unique T-lymphocyte line and products derived therefrom
US4333562A (en) * 1981-02-02 1982-06-08 Todd Michael A Capsule for storing written information

Also Published As

Publication number Publication date
IL69985A (en) 1988-05-31
WO1984001504A1 (en) 1984-04-26
DE3381082D1 (de) 1990-02-15
IE56089B1 (en) 1991-04-10
EP0122936A1 (en) 1984-10-31
IT8383481A0 (it) 1983-10-20
US4613459A (en) 1986-09-23
IE832452L (en) 1984-04-20
EP0122936A4 (en) 1985-04-25
EP0122936B1 (en) 1990-01-10
IL69985A0 (en) 1984-01-31

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