IT1202739B - 4-Alkyl-alkanoyl-7-hydroxy-coumarin prepn. in good yield - by alkanoylating corresp. unsubstituted cpd. using Friedel-Crafts catalyst - Google Patents

4-Alkyl-alkanoyl-7-hydroxy-coumarin prepn. in good yield - by alkanoylating corresp. unsubstituted cpd. using Friedel-Crafts catalyst

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Publication number
IT1202739B
IT1202739B IT2087478A IT2087478A IT1202739B IT 1202739 B IT1202739 B IT 1202739B IT 2087478 A IT2087478 A IT 2087478A IT 2087478 A IT2087478 A IT 2087478A IT 1202739 B IT1202739 B IT 1202739B
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IT
Italy
Prior art keywords
alkyl
alkanoyl
corresp
friedel
alkanoylating
Prior art date
Application number
IT2087478A
Other languages
Italian (it)
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IT7820874A0 (en
Original Assignee
Fisons Ltd
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Publication date
Application filed by Fisons Ltd filed Critical Fisons Ltd
Priority to IT2087478A priority Critical patent/IT1202739B/en
Publication of IT7820874A0 publication Critical patent/IT7820874A0/en
Application granted granted Critical
Publication of IT1202739B publication Critical patent/IT1202739B/en

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Abstract

4-Alkyl-6 (or 8)-alkanoyl-7-hydroxycoumarins of formula (I):- (where R is unsubstd. alkyl; and R1 is alkanoyl ortho to the 7-OH) are prepd. by reacting a corresp. 4-alkyl-7-hydroxycoumarin (II) with an alkanoylating agent in presence of a Friedel-crafts catalyst. Good yields of (I) in a simple process compared with the previously used Fries rearrangement; (I) are intermediates for pharmacologically active cpds.
IT2087478A 1978-03-03 1978-03-03 4-Alkyl-alkanoyl-7-hydroxy-coumarin prepn. in good yield - by alkanoylating corresp. unsubstituted cpd. using Friedel-Crafts catalyst IT1202739B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IT2087478A IT1202739B (en) 1978-03-03 1978-03-03 4-Alkyl-alkanoyl-7-hydroxy-coumarin prepn. in good yield - by alkanoylating corresp. unsubstituted cpd. using Friedel-Crafts catalyst

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2087478A IT1202739B (en) 1978-03-03 1978-03-03 4-Alkyl-alkanoyl-7-hydroxy-coumarin prepn. in good yield - by alkanoylating corresp. unsubstituted cpd. using Friedel-Crafts catalyst

Publications (2)

Publication Number Publication Date
IT7820874A0 IT7820874A0 (en) 1978-03-03
IT1202739B true IT1202739B (en) 1989-02-09

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Family Applications (1)

Application Number Title Priority Date Filing Date
IT2087478A IT1202739B (en) 1978-03-03 1978-03-03 4-Alkyl-alkanoyl-7-hydroxy-coumarin prepn. in good yield - by alkanoylating corresp. unsubstituted cpd. using Friedel-Crafts catalyst

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IT (1) IT1202739B (en)

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Publication number Publication date
IT7820874A0 (en) 1978-03-03

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