IT1200410B - Procedimento di solubilizzazione di principi attivi e composizioni farmaceutiche cosi' ottenute - Google Patents
Procedimento di solubilizzazione di principi attivi e composizioni farmaceutiche cosi' ottenuteInfo
- Publication number
- IT1200410B IT1200410B IT19873/85A IT1987385A IT1200410B IT 1200410 B IT1200410 B IT 1200410B IT 19873/85 A IT19873/85 A IT 19873/85A IT 1987385 A IT1987385 A IT 1987385A IT 1200410 B IT1200410 B IT 1200410B
- Authority
- IT
- Italy
- Prior art keywords
- pharmaceutical compositions
- active principles
- solubilization procedure
- aqueous
- solubilization
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000007928 solubilization Effects 0.000 title 1
- 238000005063 solubilization Methods 0.000 title 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 2
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 239000008346 aqueous phase Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001079 digestive effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 230000003381 solubilizing effect Effects 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Indole Compounds (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH127984 | 1984-03-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8519873A0 IT8519873A0 (it) | 1985-03-13 |
| IT1200410B true IT1200410B (it) | 1989-01-18 |
Family
ID=4206704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT19873/85A IT1200410B (it) | 1984-03-14 | 1985-03-13 | Procedimento di solubilizzazione di principi attivi e composizioni farmaceutiche cosi' ottenute |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4794117A (it) |
| EP (1) | EP0173729B1 (it) |
| JP (1) | JPS61501566A (it) |
| KR (1) | KR930000029B1 (it) |
| AT (1) | ATE57472T1 (it) |
| AU (1) | AU573321B2 (it) |
| DE (1) | DE3580140D1 (it) |
| HU (1) | HU195918B (it) |
| IT (1) | IT1200410B (it) |
| NO (1) | NO165626C (it) |
| OA (1) | OA08170A (it) |
| WO (1) | WO1985004106A1 (it) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8607662D0 (en) * | 1986-03-27 | 1986-04-30 | Rainsford K D | Pharmaceutical formulation |
| US5071643A (en) * | 1986-10-17 | 1991-12-10 | R. P. Scherer Corporation | Solvent system enhancing the solubility of pharmaceuticals for encapsulation |
| US5110493A (en) * | 1987-09-11 | 1992-05-05 | Syntex (U.S.A.) Inc. | Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant |
| ZA886757B (en) * | 1987-09-11 | 1990-05-30 | Syntex Inc | Preservative system for ophthalmics formulations |
| US5290774A (en) * | 1989-08-03 | 1994-03-01 | Eisai Co., Ltd. | Photostabilizing method for ophthalmic solutions and the resulting ophthalmic solutions therefrom |
| DE69004066T2 (de) * | 1989-08-03 | 1994-02-17 | Eisai Co Ltd | Verfahren zur photostabilisierung von augenspüllösungen. |
| DE4342907A1 (de) * | 1993-12-16 | 1995-06-22 | Bayer Ag | Neue cyclische Depsipeptide mit 18 Ringatomen und ihre Verwendung zur Bekämpfung von Endoparasiten |
| MX9701342A (es) * | 1994-09-01 | 1997-05-31 | Upjohn Co | Formulacion cosolvente de tirilazad para administracion parenteral. |
| US6274592B1 (en) * | 1997-02-04 | 2001-08-14 | Senju Pharmaceutical Co., Ltd. | Method for stabilizing arylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized arylcarboxylic acid |
| US6844004B2 (en) * | 1997-08-15 | 2005-01-18 | Board Of Regents, The University Of Texas System | Topical formulations of natamycin/pimaricin |
| US6045815A (en) * | 1997-08-15 | 2000-04-04 | Board Of Regents, The University Of Texas System | Parenteral pimaricin as treatment of systemic infections |
| US20020035107A1 (en) * | 2000-06-20 | 2002-03-21 | Stefan Henke | Highly concentrated stable meloxicam solutions |
| DE10030345A1 (de) * | 2000-06-20 | 2002-01-10 | Boehringer Ingelheim Vetmed | Hochkonzentrierte stabile Meloxicamlösungen |
| US6387400B1 (en) | 2000-08-29 | 2002-05-14 | R.P. Scherer Technologies, Inc. | Process for preparing pharmaceutical compositions for use with soft gelatin formulations |
| ITMI20012135A1 (it) | 2001-10-16 | 2003-04-16 | Bioren S A | Soluzioni iniettabili pronte all'uso di paracetamolo |
| DE10161077A1 (de) | 2001-12-12 | 2003-06-18 | Boehringer Ingelheim Vetmed | Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion |
| US8992980B2 (en) * | 2002-10-25 | 2015-03-31 | Boehringer Ingelheim Vetmedica Gmbh | Water-soluble meloxicam granules |
| FR2851164B1 (fr) | 2003-02-14 | 2005-04-22 | Xuan Tho Nguyen | Formulation liquide injectable de paracetamol |
| EP1568369A1 (en) * | 2004-02-23 | 2005-08-31 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the treatment of respiratory diseases in pigs |
| DE102004021281A1 (de) * | 2004-04-29 | 2005-11-24 | Boehringer Ingelheim Vetmedica Gmbh | Verwendung von Meloxicam-Formulierungen in der Veterinärmedizin |
| DE102004030409A1 (de) * | 2004-06-23 | 2006-01-26 | Boehringer Ingelheim Vetmedica Gmbh | Neue Verwendung von Meloxicam in der Veterinärmedizin |
| NZ567627A (en) * | 2005-09-30 | 2011-08-26 | Boehringer Ingelheim Vetmed | Granulation process for making a divisible tablet containing meloxicam |
| BRPI0905707B1 (pt) * | 2008-01-18 | 2024-02-27 | Dow Global Technologies Inc | Método para aumentar a solubilidade aquosa de um composto ativo e composição compreendendo um composto ativo |
| JP4959006B2 (ja) * | 2009-02-03 | 2012-06-20 | サンスター株式会社 | ヘスペリジン含有組成物 |
| WO2011046853A1 (en) * | 2009-10-12 | 2011-04-21 | Boehringer Ingelheim Vetmedica Gmbh | Containers for compositions comprising meloxicam |
| US20110218191A1 (en) * | 2010-03-03 | 2011-09-08 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the long term-treatment of kidney disorders in cats |
| MX2012010077A (es) | 2010-03-03 | 2012-09-12 | Boehringer Ingelheim Vetmed | Uso de meloxicam para el tratamiento a largo plazo de trastornos musculoesqueleticos en gatos. |
| US9795568B2 (en) | 2010-05-05 | 2017-10-24 | Boehringer Ingelheim Vetmedica Gmbh | Low concentration meloxicam tablets |
| US20120022149A1 (en) * | 2010-07-21 | 2012-01-26 | Chowhan Masood A | Pharmaceutical composition with enhanced solubility characteristics |
| GB201321743D0 (en) * | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic agents |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1916432A1 (de) * | 1969-03-31 | 1970-10-08 | Dresden Arzneimittel | Verfahren zur Herstellung von Injektionsloesungen von therapeutisch wertvollen Benzodiazepinderivaten und ihren Kombinationen mit anderen Wirkstoffen |
| IL33774A0 (en) * | 1970-01-26 | 1970-03-22 | Abic Ltd | A water-soluble composition comprising sulfadimidine and pyrimethamine |
| DK138974B (da) * | 1974-02-19 | 1978-11-27 | Ciba Geigy Ag | Fremgangsmåde til fremstilling af vandige oxytetracyclinopløsninger til parenteral, peroral og lokal anvendelse. |
| DE3006024C2 (de) * | 1980-02-18 | 1983-08-04 | Solvon Arzneimittel-Vertriebs- Und Lizenzgesellschaft Mbh, 85011 Burgthann | Topisches, Indomethacin enthaltendes Arzneimittel in Salbenform |
-
1985
- 1985-03-12 EP EP85901459A patent/EP0173729B1/fr not_active Expired - Lifetime
- 1985-03-12 KR KR1019850700302A patent/KR930000029B1/ko not_active Expired - Fee Related
- 1985-03-12 JP JP60501181A patent/JPS61501566A/ja active Pending
- 1985-03-12 WO PCT/FR1985/000050 patent/WO1985004106A1/fr not_active Ceased
- 1985-03-12 AU AU40645/85A patent/AU573321B2/en not_active Ceased
- 1985-03-12 DE DE8585901459T patent/DE3580140D1/de not_active Expired - Lifetime
- 1985-03-12 AT AT85901459T patent/ATE57472T1/de active
- 1985-03-12 HU HU851440A patent/HU195918B/hu not_active IP Right Cessation
- 1985-03-13 IT IT19873/85A patent/IT1200410B/it active
- 1985-11-08 NO NO85854461A patent/NO165626C/no unknown
- 1985-11-13 OA OA58722A patent/OA08170A/xx unknown
-
1987
- 1987-09-30 US US07/103,451 patent/US4794117A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NO165626B (no) | 1990-12-03 |
| IT8519873A0 (it) | 1985-03-13 |
| NO165626C (no) | 1991-03-13 |
| OA08170A (fr) | 1987-03-31 |
| HU195918B (en) | 1988-08-29 |
| US4794117A (en) | 1988-12-27 |
| KR930000029B1 (ko) | 1993-01-06 |
| AU4064585A (en) | 1985-10-11 |
| EP0173729A1 (fr) | 1986-03-12 |
| AU573321B2 (en) | 1988-06-02 |
| KR850700216A (ko) | 1985-12-26 |
| DE3580140D1 (de) | 1990-11-22 |
| ATE57472T1 (de) | 1990-11-15 |
| JPS61501566A (ja) | 1986-07-31 |
| EP0173729B1 (fr) | 1990-10-17 |
| NO854461L (no) | 1985-11-08 |
| WO1985004106A1 (fr) | 1985-09-26 |
| HUT38263A (en) | 1986-05-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970430 |