IT1189298B - Procedimento per produrre i glicosa minoglicani dermatansolfato ed eparan-solfato sostanzialmente puri e loro impiego farmaceutico - Google Patents

Procedimento per produrre i glicosa minoglicani dermatansolfato ed eparan-solfato sostanzialmente puri e loro impiego farmaceutico

Info

Publication number
IT1189298B
IT1189298B IT48666/82A IT4866682A IT1189298B IT 1189298 B IT1189298 B IT 1189298B IT 48666/82 A IT48666/82 A IT 48666/82A IT 4866682 A IT4866682 A IT 4866682A IT 1189298 B IT1189298 B IT 1189298B
Authority
IT
Italy
Prior art keywords
sulphate
dermatan
substantially pure
minoglicans
eparan
Prior art date
Application number
IT48666/82A
Other languages
English (en)
Other versions
IT8248666A0 (it
Inventor
Giovanni Orzalesi
Ivo Volpato
Renzo Cappelletti
Original Assignee
Manetti & Roberts Italo Brit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Manetti & Roberts Italo Brit filed Critical Manetti & Roberts Italo Brit
Priority to IT48666/82A priority Critical patent/IT1189298B/it
Publication of IT8248666A0 publication Critical patent/IT8248666A0/it
Priority to EP83830122A priority patent/EP0097625B1/en
Priority to AT83830122T priority patent/ATE33253T1/de
Priority to DE8383830122T priority patent/DE3376116D1/de
Application granted granted Critical
Publication of IT1189298B publication Critical patent/IT1189298B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
IT48666/82A 1982-06-18 1982-06-18 Procedimento per produrre i glicosa minoglicani dermatansolfato ed eparan-solfato sostanzialmente puri e loro impiego farmaceutico IT1189298B (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IT48666/82A IT1189298B (it) 1982-06-18 1982-06-18 Procedimento per produrre i glicosa minoglicani dermatansolfato ed eparan-solfato sostanzialmente puri e loro impiego farmaceutico
EP83830122A EP0097625B1 (en) 1982-06-18 1983-06-17 Process for producing substantially pure dermatan sulfate and heparan sulfate glycosaminoglycans, and pharmaceutical use thereof
AT83830122T ATE33253T1 (de) 1982-06-18 1983-06-17 Verfahren zur herstellung von reinen dermatansulfat- und herapansulfatglykosaminoglukanen und ihre pharmazeutische verwendung.
DE8383830122T DE3376116D1 (en) 1982-06-18 1983-06-17 Process for producing substantially pure dermatan sulfate and heparan sulfate glycosaminoglycans, and pharmaceutical use thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT48666/82A IT1189298B (it) 1982-06-18 1982-06-18 Procedimento per produrre i glicosa minoglicani dermatansolfato ed eparan-solfato sostanzialmente puri e loro impiego farmaceutico

Publications (2)

Publication Number Publication Date
IT8248666A0 IT8248666A0 (it) 1982-06-18
IT1189298B true IT1189298B (it) 1988-02-04

Family

ID=11267926

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48666/82A IT1189298B (it) 1982-06-18 1982-06-18 Procedimento per produrre i glicosa minoglicani dermatansolfato ed eparan-solfato sostanzialmente puri e loro impiego farmaceutico

Country Status (4)

Country Link
EP (1) EP0097625B1 (it)
AT (1) ATE33253T1 (it)
DE (1) DE3376116D1 (it)
IT (1) IT1189298B (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1163772B (it) * 1983-07-13 1987-04-08 Baldacci Lab Spa Oligosaccaridi eterogenei complessabili ed alfa-idosani ad attivita' terapeutica, procedimento per la loro preparazione e relative composizioni farmaceutiche
IT1208509B (it) * 1985-03-13 1989-07-10 Mediolanum Farmaceutici Srl Processo per la produzione di eparan solfato e dermatan solfato naturali sostanzialmente puri eloro impiego farmaceutico.
IT1189085B (it) * 1986-03-25 1988-01-28 Mediolanum Farmaceutici Srl Processo per la preparazione di dermatan solfato ad alta purezza e composizioni farmaceutiche che lo contengono
IT1196634B (it) * 1986-09-19 1988-11-16 Farmaceutici Damor Spa Procedimento per la produzione di eparan-lisopeptide-solfato prodotto cosi' ottenuto e suo impiego terapeutico
US4879282A (en) * 1987-03-17 1989-11-07 Saliba Jr Michael J Medical application for heparin and related molecules
DK505488D0 (da) * 1987-12-21 1988-09-09 Bar Shalom Daniel Middel og anvendelse af samme
US5916880A (en) * 1987-12-21 1999-06-29 Bukh Meditec A/S Reduction of skin wrinkling using sulphated sugars
US5709873A (en) * 1988-02-26 1998-01-20 Niels Bukh A/S Method of treating conditions of teeth and their supporting tissue
DK505588D0 (da) * 1988-02-26 1988-09-09 Jesper Hamburger Middel og anvendelse af samme
US5618798A (en) * 1989-04-20 1997-04-08 Bar-Shalom; Daniel Use of sucralfate to treat baldness
CN103183746B (zh) * 2012-09-19 2015-05-27 杭州龙扬生物科技有限公司 猪小肠综合提取肝素钠的工艺
ITMI20121597A1 (it) 2012-09-25 2014-03-26 Beta Pharma S A Coniugato tra frammento di parete cellulare batterica ed un veicolo mucopolisaccaridico e suoi usi in ambito medico
CN106666484B (zh) * 2016-12-23 2019-12-20 古鲟（大连）生物科技发展有限公司 鲟鱼复合粉、鲟鱼骨酒及应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1221784A (en) * 1967-04-07 1971-02-10 John Ernest Scott Precipitation of heparin from aqueous solution

Also Published As

Publication number Publication date
EP0097625A3 (en) 1985-05-15
EP0097625A2 (en) 1984-01-04
ATE33253T1 (de) 1988-04-15
DE3376116D1 (en) 1988-05-05
IT8248666A0 (it) 1982-06-18
EP0097625B1 (en) 1988-03-30

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970429