IT1187699B - 1-(2-pirimidinil)-piperazinil derivati di 1-pirrolidin-2-onipsicogeriatrici - Google Patents

1-(2-pirimidinil)-piperazinil derivati di 1-pirrolidin-2-onipsicogeriatrici

Info

Publication number
IT1187699B
IT1187699B IT21657/85A IT2165785A IT1187699B IT 1187699 B IT1187699 B IT 1187699B IT 21657/85 A IT21657/85 A IT 21657/85A IT 2165785 A IT2165785 A IT 2165785A IT 1187699 B IT1187699 B IT 1187699B
Authority
IT
Italy
Prior art keywords
onipsychogenators
pyrolidin
pyrimidinyl
piperazinyl derivatives
piperazinyl
Prior art date
Application number
IT21657/85A
Other languages
English (en)
Italian (it)
Other versions
IT8521657A0 (it
Inventor
Joseph P Yevich
Ronald J Mattson
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IT8521657A0 publication Critical patent/IT8521657A0/it
Application granted granted Critical
Publication of IT1187699B publication Critical patent/IT1187699B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT21657/85A 1984-07-23 1985-07-22 1-(2-pirimidinil)-piperazinil derivati di 1-pirrolidin-2-onipsicogeriatrici IT1187699B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63337184A 1984-07-23 1984-07-23

Publications (2)

Publication Number Publication Date
IT8521657A0 IT8521657A0 (it) 1985-07-22
IT1187699B true IT1187699B (it) 1987-12-23

Family

ID=24539376

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21657/85A IT1187699B (it) 1984-07-23 1985-07-22 1-(2-pirimidinil)-piperazinil derivati di 1-pirrolidin-2-onipsicogeriatrici

Country Status (8)

Country Link
JP (1) JPS61106570A (fr)
CA (1) CA1250291A (fr)
DK (1) DK333485A (fr)
FR (1) FR2567886B1 (fr)
GB (1) GB2162843B (fr)
HU (1) HU194874B (fr)
IT (1) IT1187699B (fr)
SE (1) SE463715B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1322199C (fr) * 1987-07-15 1993-09-14 Masami Eigyo Derives n-(2 oxopyrrolidin-1-yl) acetylpiperazine et medicaments pour la demence senile
US5340812A (en) * 1989-04-22 1994-08-23 John Wyeth & Brother, Limited Piperazine derivatives
FI102175B1 (fi) * 1989-04-22 1998-10-30 Wyeth John & Brother Ltd Menetelmä terapeuttisesti käyttökelpoisten piperatsiinijohdannaisten valmistamiseksi
GB8917687D0 (en) * 1989-08-02 1989-09-20 Fujisawa Pharmaceutical Co Aminopiperazine derivatives,processes for preparation thereof and pharmaceutical composition comprising the same
US5250528A (en) * 1989-08-02 1993-10-05 Fujisawa Pharmaceutical Co., Ltd. New aminopiperazine derivatives
BR9812736A (pt) * 1997-10-09 2000-08-22 Fujisawa Pharmaceutical Co Novo processo para produzir derivados de aminopiperazina

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
US4423049A (en) * 1981-12-28 1983-12-27 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyrimidines
DE3361609D1 (en) * 1982-03-24 1986-02-06 Prodes Sa New n-((2-oxo-1-pyrrolidinyl)acetyl)piperazines, the methods of producing such new compounds and their salts as well as pharmaceutical preparations for therapeutic use containing these compounds or salts

Also Published As

Publication number Publication date
CA1250291A (fr) 1989-02-21
IT8521657A0 (it) 1985-07-22
GB2162843A (en) 1986-02-12
SE8503557D0 (sv) 1985-07-22
SE463715B (sv) 1991-01-14
GB2162843B (en) 1988-04-20
FR2567886A1 (fr) 1986-01-24
JPS61106570A (ja) 1986-05-24
HU194874B (en) 1988-03-28
SE8503557L (sv) 1986-01-24
DK333485A (da) 1986-01-24
HUT38342A (en) 1986-05-28
FR2567886B1 (fr) 1988-03-25
GB8518452D0 (en) 1985-08-29
DK333485D0 (da) 1985-07-22

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