FR2567886B1 - Derives 1-(2-pyrimidinyl)-piperazinyliques de 1-pyrrolidine-2-ones et leur application psychogeriatrique - Google Patents

Derives 1-(2-pyrimidinyl)-piperazinyliques de 1-pyrrolidine-2-ones et leur application psychogeriatrique

Info

Publication number
FR2567886B1
FR2567886B1 FR8511172A FR8511172A FR2567886B1 FR 2567886 B1 FR2567886 B1 FR 2567886B1 FR 8511172 A FR8511172 A FR 8511172A FR 8511172 A FR8511172 A FR 8511172A FR 2567886 B1 FR2567886 B1 FR 2567886B1
Authority
FR
France
Prior art keywords
psychogeriatric
pyrimidinyl
pyrrolidine
ones
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8511172A
Other languages
English (en)
Other versions
FR2567886A1 (fr
Inventor
Joseph P Yevich
Ronald J Mattson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FR2567886A1 publication Critical patent/FR2567886A1/fr
Application granted granted Critical
Publication of FR2567886B1 publication Critical patent/FR2567886B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR8511172A 1984-07-23 1985-07-22 Derives 1-(2-pyrimidinyl)-piperazinyliques de 1-pyrrolidine-2-ones et leur application psychogeriatrique Expired FR2567886B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63337184A 1984-07-23 1984-07-23

Publications (2)

Publication Number Publication Date
FR2567886A1 FR2567886A1 (fr) 1986-01-24
FR2567886B1 true FR2567886B1 (fr) 1988-03-25

Family

ID=24539376

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8511172A Expired FR2567886B1 (fr) 1984-07-23 1985-07-22 Derives 1-(2-pyrimidinyl)-piperazinyliques de 1-pyrrolidine-2-ones et leur application psychogeriatrique

Country Status (8)

Country Link
JP (1) JPS61106570A (fr)
CA (1) CA1250291A (fr)
DK (1) DK333485A (fr)
FR (1) FR2567886B1 (fr)
GB (1) GB2162843B (fr)
HU (1) HU194874B (fr)
IT (1) IT1187699B (fr)
SE (1) SE463715B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1322199C (fr) * 1987-07-15 1993-09-14 Masami Eigyo Derives n-(2 oxopyrrolidin-1-yl) acetylpiperazine et medicaments pour la demence senile
KR0173310B1 (ko) * 1989-04-22 1999-02-01 폴 에이 리쳐 피페라진 유도체
US5340812A (en) * 1989-04-22 1994-08-23 John Wyeth & Brother, Limited Piperazine derivatives
US5250528A (en) * 1989-08-02 1993-10-05 Fujisawa Pharmaceutical Co., Ltd. New aminopiperazine derivatives
GB8917687D0 (en) * 1989-08-02 1989-09-20 Fujisawa Pharmaceutical Co Aminopiperazine derivatives,processes for preparation thereof and pharmaceutical composition comprising the same
EP1043320A4 (fr) * 1997-10-09 2000-12-06 Fujisawa Pharmaceutical Co Nouveau procede de production de derives d'aminopiperazine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
US4423049A (en) * 1981-12-28 1983-12-27 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyrimidines
EP0089900B1 (fr) * 1982-03-24 1985-12-27 Prodes S.A. N-((2-oxo-1-pyrrolidinyl)acétyl)pipérazines, procédés pour leur préparation et leurs sels, ainsi que leur utilisation dans des préparations pharmaceutiques

Also Published As

Publication number Publication date
DK333485D0 (da) 1985-07-22
FR2567886A1 (fr) 1986-01-24
SE8503557D0 (sv) 1985-07-22
HU194874B (en) 1988-03-28
SE463715B (sv) 1991-01-14
CA1250291A (fr) 1989-02-21
IT1187699B (it) 1987-12-23
GB8518452D0 (en) 1985-08-29
GB2162843A (en) 1986-02-12
HUT38342A (en) 1986-05-28
GB2162843B (en) 1988-04-20
IT8521657A0 (it) 1985-07-22
JPS61106570A (ja) 1986-05-24
SE8503557L (sv) 1986-01-24
DK333485A (da) 1986-01-24

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Legal Events

Date Code Title Description
ST Notification of lapse