IT1178255B - Derivati butanolici dotati di attivita' antiaritmica e procedimento di preparazione - Google Patents

Derivati butanolici dotati di attivita' antiaritmica e procedimento di preparazione

Info

Publication number
IT1178255B
IT1178255B IT49192/84A IT4919284A IT1178255B IT 1178255 B IT1178255 B IT 1178255B IT 49192/84 A IT49192/84 A IT 49192/84A IT 4919284 A IT4919284 A IT 4919284A IT 1178255 B IT1178255 B IT 1178255B
Authority
IT
Italy
Prior art keywords
butanolic
preparation procedure
arrhythmic activity
derivatives
derivatives equipped
Prior art date
Application number
IT49192/84A
Other languages
English (en)
Other versions
IT8449192A1 (it
IT8449192A0 (it
Inventor
Kiyoshi Kimura
Takeshi Yamaguchi
Iwao Morita
Tetsuo Murakami
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Publication of IT8449192A0 publication Critical patent/IT8449192A0/it
Publication of IT8449192A1 publication Critical patent/IT8449192A1/it
Application granted granted Critical
Publication of IT1178255B publication Critical patent/IT1178255B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/30—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
    • C07C215/32—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton containing hydroxy groups and carbon atoms of two six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/64—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
    • C07C217/66—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms with singly-bound oxygen atoms and six-membered aromatic rings bound to the same carbon atom of the carbon chain
    • C07C217/72—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms with singly-bound oxygen atoms and six-membered aromatic rings bound to the same carbon atom of the carbon chain linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT49192/84A 1983-11-21 1984-11-20 Derivati butanolici dotati di attivita' antiaritmica e procedimento di preparazione IT1178255B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58220342A JPS60132934A (ja) 1983-11-21 1983-11-21 ブタノ−ル誘導体

Publications (3)

Publication Number Publication Date
IT8449192A0 IT8449192A0 (it) 1984-11-20
IT8449192A1 IT8449192A1 (it) 1986-05-20
IT1178255B true IT1178255B (it) 1987-09-09

Family

ID=16749640

Family Applications (1)

Application Number Title Priority Date Filing Date
IT49192/84A IT1178255B (it) 1983-11-21 1984-11-20 Derivati butanolici dotati di attivita' antiaritmica e procedimento di preparazione

Country Status (10)

Country Link
US (1) US5089529A (it)
JP (1) JPS60132934A (it)
KR (2) KR850004098A (it)
CA (1) CA1241345A (it)
CH (1) CH662111A5 (it)
DE (1) DE3442648A1 (it)
ES (1) ES537789A0 (it)
FR (1) FR2555168B1 (it)
GB (1) GB2150134B (it)
IT (1) IT1178255B (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2415678A1 (en) * 2000-07-13 2003-01-10 Sankyo Company Limited Amino alcohol derivatives

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2441664A (en) * 1947-08-09 1948-05-18 Lucille E Hoagland Means for lengthening skirts
US2584429A (en) * 1950-12-29 1952-02-05 Rohm & Haas 1,1-diphenyl-4-tert.-amino-2-butyne-1-ols
US2682543A (en) * 1951-05-26 1954-06-29 Burroughs Wellcome Co Catalytic reduction of diphenyl alkanolamines and resulting products
GB993525A (en) * 1961-05-19 1965-05-26 Smith Kline French Lab Substituted propanolamines and process for preparing the same
NL63794C (it) * 1961-10-10
DK114828B (da) * 1962-11-29 1969-08-11 Hoffmann La Roche Fremgangsmåde til fremstilling af 5-hydroxy-5-aminoalkyl-10,11-dihydro-5H-dibenzo-(a,d)-cykloheptener eller syreadditionssalte deraf.
AT255400B (de) * 1965-03-22 1967-07-10 Chemie Linz Ag Verfahren zur Herstellung von neuen basischen Äthern
AT316516B (de) * 1970-12-09 1974-07-10 Sumitomo Chemical Co Verfahren zur Herstellung von neuen Aminoalkoholen und von deren Säureadditionssalzen
US4277471A (en) * 1979-03-12 1981-07-07 Eli Lilly And Company 1,1-Biphenyl-2-yl alkylamines, formulations and antiarrhythmic treatment

Also Published As

Publication number Publication date
JPS60132934A (ja) 1985-07-16
GB2150134A (en) 1985-06-26
IT8449192A1 (it) 1986-05-20
KR850004098A (ko) 1985-07-01
DE3442648A1 (de) 1985-05-30
IT8449192A0 (it) 1984-11-20
CA1241345A (en) 1988-08-30
JPH0246024B2 (it) 1990-10-12
ES8601095A1 (es) 1985-10-16
ES537789A0 (es) 1985-10-16
KR860004008A (ko) 1986-06-16
GB8427829D0 (en) 1984-12-12
FR2555168A1 (fr) 1985-05-24
CH662111A5 (fr) 1987-09-15
GB2150134B (en) 1987-11-11
US5089529A (en) 1992-02-18
FR2555168B1 (fr) 1987-06-19

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