IT1176321B - Estere dell'acido salicilico avente attivita' mucosecretolitica,antinfiammatoria,analgesica,antipiretica adatto a dare sali farmaceuticamente accettabili; procedimento per la preparazione,e composizioni farmaceutiche contenenti l'estere o i suoi sali - Google Patents
Estere dell'acido salicilico avente attivita' mucosecretolitica,antinfiammatoria,analgesica,antipiretica adatto a dare sali farmaceuticamente accettabili; procedimento per la preparazione,e composizioni farmaceutiche contenenti l'estere o i suoi saliInfo
- Publication number
- IT1176321B IT1176321B IT21608/84A IT2160884A IT1176321B IT 1176321 B IT1176321 B IT 1176321B IT 21608/84 A IT21608/84 A IT 21608/84A IT 2160884 A IT2160884 A IT 2160884A IT 1176321 B IT1176321 B IT 1176321B
- Authority
- IT
- Italy
- Prior art keywords
- salts
- mucosecretolytic
- analgesic
- inflammatory
- pharmaceutically acceptable
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 3
- 230000000202 analgesic effect Effects 0.000 title abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
- 230000001569 mucosecretolytic effect Effects 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 230000000694 effects Effects 0.000 title 1
- 150000003902 salicylic acid esters Chemical class 0.000 title 1
- 150000002148 esters Chemical class 0.000 abstract 2
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 150000007529 inorganic bases Chemical class 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- -1 salicyclic acid ester Chemical class 0.000 abstract 1
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
- C07C69/86—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified hydroxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/14—Preparation of carboxylic acid esters from carboxylic acid halides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/608—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a ring other than a six-membered aromatic ring in the acid moiety
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT21608/84A IT1176321B (it) | 1984-06-26 | 1984-06-26 | Estere dell'acido salicilico avente attivita' mucosecretolitica,antinfiammatoria,analgesica,antipiretica adatto a dare sali farmaceuticamente accettabili; procedimento per la preparazione,e composizioni farmaceutiche contenenti l'estere o i suoi sali |
| EP85105645A EP0166918B1 (en) | 1984-06-26 | 1985-05-08 | A (-) campholenic acid ester of salicylic acid having mucosecretolytic, anti-inflammatory, analgesic antipyretic activity, suitable to provide pharmaceutically acceptable salts; a process for its preparation and pharmaceutical compositions containing the ester or the salts thereof |
| AT85105645T ATE44463T1 (de) | 1984-06-26 | 1985-05-08 | Salicylsaeureester der (-)campholensaeure mit mucosekretolytischer, entzuendungshemmender, schmerzstillender, fieber erniedrigender wirkung, welcher pharmazeutisch annehmbare salze bilden kann, sein herstellungsverfahren und pharmazeutische zusammensetzungen die den ester oder eines seiner salze enthalten. |
| DE8585105645T DE3571394D1 (en) | 1984-06-26 | 1985-05-08 | A (-) campholenic acid ester of salicylic acid having mucosecretolytic, anti-inflammatory, analgesic antipyretic activity, suitable to provide pharmaceutically acceptable salts; a process for its preparation and pharmaceutical compositions containing the ester or the salts thereof |
| JP9814285A JPS6133143A (ja) | 1984-06-26 | 1985-05-10 | (−)カンフオレン酸エステル及びその塩の製造方法並びにその医薬組成物 |
| US06/734,067 US4631293A (en) | 1984-06-26 | 1985-05-15 | (-) Campholenic acid ester of salicylic acid and pharmaceutically acceptable salts thereof having mucosecretolytic, anti-inflammatory, analgesic, and antipyretic activity |
| KR1019850004510A KR920004457B1 (ko) | 1984-06-26 | 1985-06-25 | 살리실산의 (-)캄포렌산 에스테르의 제조방법 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT21608/84A IT1176321B (it) | 1984-06-26 | 1984-06-26 | Estere dell'acido salicilico avente attivita' mucosecretolitica,antinfiammatoria,analgesica,antipiretica adatto a dare sali farmaceuticamente accettabili; procedimento per la preparazione,e composizioni farmaceutiche contenenti l'estere o i suoi sali |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IT8421608A0 IT8421608A0 (it) | 1984-06-26 |
| IT8421608A1 IT8421608A1 (it) | 1985-12-26 |
| IT1176321B true IT1176321B (it) | 1987-08-18 |
Family
ID=11184267
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT21608/84A IT1176321B (it) | 1984-06-26 | 1984-06-26 | Estere dell'acido salicilico avente attivita' mucosecretolitica,antinfiammatoria,analgesica,antipiretica adatto a dare sali farmaceuticamente accettabili; procedimento per la preparazione,e composizioni farmaceutiche contenenti l'estere o i suoi sali |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4631293A (it) |
| EP (1) | EP0166918B1 (it) |
| JP (1) | JPS6133143A (it) |
| KR (1) | KR920004457B1 (it) |
| AT (1) | ATE44463T1 (it) |
| DE (1) | DE3571394D1 (it) |
| IT (1) | IT1176321B (it) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2561193A (en) * | 1949-05-20 | 1951-07-17 | Dow Chemical Co | alpha-methyl benzyl esters of campholic and fencholic acids |
| US2835697A (en) * | 1956-05-10 | 1958-05-20 | Upjohn Co | Salicylic acid beta-cyclopentylopropionate |
| NL6604303A (it) * | 1965-04-01 | 1966-10-03 | ||
| CH495111A (de) * | 1968-03-14 | 1970-08-31 | Ciba Geigy | Schädlingsbekämpfungsmittel |
-
1984
- 1984-06-26 IT IT21608/84A patent/IT1176321B/it active
-
1985
- 1985-05-08 DE DE8585105645T patent/DE3571394D1/de not_active Expired
- 1985-05-08 EP EP85105645A patent/EP0166918B1/en not_active Expired
- 1985-05-08 AT AT85105645T patent/ATE44463T1/de not_active IP Right Cessation
- 1985-05-10 JP JP9814285A patent/JPS6133143A/ja active Granted
- 1985-05-15 US US06/734,067 patent/US4631293A/en not_active Expired - Fee Related
- 1985-06-25 KR KR1019850004510A patent/KR920004457B1/ko not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE3571394D1 (en) | 1989-08-17 |
| IT8421608A1 (it) | 1985-12-26 |
| EP0166918A3 (en) | 1986-06-11 |
| JPS6133143A (ja) | 1986-02-17 |
| EP0166918B1 (en) | 1989-07-12 |
| IT8421608A0 (it) | 1984-06-26 |
| KR920004457B1 (ko) | 1992-06-05 |
| KR860000241A (ko) | 1986-01-27 |
| US4631293A (en) | 1986-12-23 |
| ATE44463T1 (de) | 1989-07-15 |
| EP0166918A2 (en) | 1986-01-08 |
| JPH0153859B2 (it) | 1989-11-15 |
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