IT1131826B - Rheumatoid arthritis treatment - Google Patents
Rheumatoid arthritis treatmentInfo
- Publication number
- IT1131826B IT1131826B IT22778/80A IT2277880A IT1131826B IT 1131826 B IT1131826 B IT 1131826B IT 22778/80 A IT22778/80 A IT 22778/80A IT 2277880 A IT2277880 A IT 2277880A IT 1131826 B IT1131826 B IT 1131826B
- Authority
- IT
- Italy
- Prior art keywords
- rifamycin
- salts
- intra
- rheumatoid arthritis
- articular injection
- Prior art date
Links
- 206010039073 rheumatoid arthritis Diseases 0.000 title abstract 2
- HJYYPODYNSCCOU-ODRIEIDWSA-N rifamycin SV Chemical compound OC1=C(C(O)=C2C)C3=C(O)C=C1NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2=C3C1=O HJYYPODYNSCCOU-ODRIEIDWSA-N 0.000 abstract 5
- 238000002347 injection Methods 0.000 abstract 4
- 239000007924 injection Substances 0.000 abstract 4
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 abstract 2
- HJYYPODYNSCCOU-ZDHWWVNNSA-N Rifamycin SV Natural products COC1C=COC2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)C(=C/C=C/C(C)C(O)C(C)C(O)C(C)C(OC(=O)C)C1C)C)cc(O)c4c3C2=O HJYYPODYNSCCOU-ZDHWWVNNSA-N 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 235000006708 antioxidants Nutrition 0.000 abstract 1
- 229960005070 ascorbic acid Drugs 0.000 abstract 1
- 235000010323 ascorbic acid Nutrition 0.000 abstract 1
- 239000011668 ascorbic acid Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229940109171 rifamycin sv Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
New use of rifamycin SV and its salts is in the form of prepns. for intra-articular injection for combatting rheumatoid arthritis. New process for the prodn. of dry prepns. for intra-articular injection contg. rifamycin SV salts comprises dehydrating aq. solns. of rifamycin SV salts. Conventional rifamycin SV salt solns. for injection contain ascorbic acid as on antioxidant and polyvinylpyrrolidone to increase bioavailability and improve local tolerance. For intra-articular injection, the presence of polyvinylpyrrolidone is undesirable. Pref. formulations, contain practically anhydrous rifamycin SV salts and no further additives.
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22778/80A IT1131826B (en) | 1980-06-13 | 1980-06-13 | Rheumatoid arthritis treatment |
SE8004965A SE458505B (en) | 1979-07-10 | 1980-07-04 | APPLICATION OF RIFAMYCIN SV AND SALTS THEREOF PREPARING A PREPARATION FOR TREATMENT OF REUMATOID ARTHRITIS AND CERTAIN SALTS AND THEIR PREPARATION |
US06/166,587 US4312866A (en) | 1979-07-10 | 1980-07-07 | Use of rifamycin SV and its related salts in the treatment of rheumatoid arthritis, and related formulations suited for the purpose |
ES493216A ES493216A0 (en) | 1979-07-10 | 1980-07-09 | PROCEDURE FOR THE PREPARATION OF SALT OF RIFAMICINA SV AQUOSOLUBLES |
FR8015261A FR2460669B1 (en) | 1979-07-10 | 1980-07-09 | PHARMACEUTICAL COMPOSITIONS BASED ON RIFAMYCIN SV AND ITS SALTS SUITABLE FOR THE TREATMENT OF JOINT RHUMATISM AND PROCESS FOR THEIR PREPARATION |
GB8022391A GB2056276B (en) | 1979-07-10 | 1980-07-09 | Formulation of rifamycin sv and salts derived therefrom for treating rheumatoid arthritis |
DE3026180A DE3026180C2 (en) | 1979-07-10 | 1980-07-10 | Rifamycin SV salts of basic amino acids, processes for their preparation and drugs for intra-articular injection in the fight against rheumatoid arthritis |
DE3050802A DE3050802C2 (en) | 1979-07-10 | 1980-07-10 | Use of Rifamycin SV sodium salt in the intra-articular control of rheumatoid arthritis |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22778/80A IT1131826B (en) | 1980-06-13 | 1980-06-13 | Rheumatoid arthritis treatment |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8022778A0 IT8022778A0 (en) | 1980-06-13 |
IT1131826B true IT1131826B (en) | 1986-06-25 |
Family
ID=11200361
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT22778/80A IT1131826B (en) | 1979-07-10 | 1980-06-13 | Rheumatoid arthritis treatment |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1131826B (en) |
-
1980
- 1980-06-13 IT IT22778/80A patent/IT1131826B/en active
Also Published As
Publication number | Publication date |
---|---|
IT8022778A0 (en) | 1980-06-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BG42835A3 (en) | Method for preparing derivatives of thiazolylacetic acid | |
IT1131826B (en) | Rheumatoid arthritis treatment | |
IE40671B1 (en) | Antibiotic method and pharaceutical compositions | |
JPS5679622A (en) | Antitumor pharmaceutical | |
GB1490290A (en) | Preparation of penicillanic acid derivatives | |
JPS5233272A (en) | Method of storing articles by using movable floor to reduce dead space by pillers | |
AU545390B2 (en) | Dimeric penicillin derivatives | |
PH20548A (en) | Novel penem compounds,pharmaceutical compositions containing them and method of using said compounds | |
JPS5367678A (en) | Treating method for by-product formed in process of treating exhaust gasby irradiation of radiation | |
JPS5236689A (en) | Novel synthetic penicillins and their preparation process | |
FR2190410A1 (en) | 7-(Aminoalkyl)theophylline salts - with a bis(2-carboxychromon-5-yloxy)alkane with prolonged prophylactic action against bronchospasm | |
JPS525755A (en) | Process for preparation of 3-amino-4-homotwistane and its acid salts | |
JPS51138664A (en) | Process for preparing 4-exo-hydroxy-endo-tri cyclo 95.2.2.02,6)-undeca-8-ene | |
IT1209298B (en) | Nifedipine topical administration compsn. | |
FR2274283A1 (en) | Vincamine 2-(para hydroxy benzoyl) benzoate - vasodilator and cerebral oxygenator-from salts of vincamine and the substd benzoic acid | |
JPS5219387A (en) | Automatic lathe | |
JPS53111092A (en) | Novel penicillin derivative | |
JPS525786A (en) | Preparation of 3-cephem-3,4-dicarboxylic acid derivativese | |
FR2211225A1 (en) | Coronary and vasodilating dihydro apouincaminic acid amines - prepd. from corresp. acid and a nitrogen heterocycle, also used as hypotensives | |
JPS5283393A (en) | Synthesis of novel penicillin derivatives | |
IT1209404B (en) | Pharmaceutical purine salts | |
FR2312506A2 (en) | Pyrimidine phosphoric esters - insecticides, acaricides, ovicides and/or nematocides | |
AT268286B (en) | Process for the preparation of the new 6- (β-dimethylaminopropyl) -pyrido [2,3-b] [1,5] -benzodiazepine (6H) 5-one as well as its non-toxic acid addition salts | |
OA06266A (en) | Process for preparing an extract of globularia useful in particular in therapy. | |
ES416905A2 (en) | Cephalosporin compounds |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19960506 |