IT1109011B - Procedimento per la produzione di vincadifformina - Google Patents
Procedimento per la produzione di vincadifforminaInfo
- Publication number
- IT1109011B IT1109011B IT09692/78A IT969278A IT1109011B IT 1109011 B IT1109011 B IT 1109011B IT 09692/78 A IT09692/78 A IT 09692/78A IT 969278 A IT969278 A IT 969278A IT 1109011 B IT1109011 B IT 1109011B
- Authority
- IT
- Italy
- Prior art keywords
- vincadifformina
- procedure
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/30—Compounds having groups
- C07C43/313—Compounds having groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/48—Preparation of compounds having groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/30—Compounds having groups
- C07C43/315—Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/865,657 US4154943A (en) | 1977-12-29 | 1977-12-29 | Preparation of vincadifformine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT7809692A0 IT7809692A0 (it) | 1978-12-29 |
| IT1109011B true IT1109011B (it) | 1985-12-16 |
Family
ID=25345973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT09692/78A IT1109011B (it) | 1977-12-29 | 1978-12-29 | Procedimento per la produzione di vincadifformina |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4154943A (OSRAM) |
| JP (1) | JPS5498800A (OSRAM) |
| BE (1) | BE873136A (OSRAM) |
| CA (1) | CA1098903A (OSRAM) |
| ES (1) | ES476504A1 (OSRAM) |
| FR (1) | FR2413391A1 (OSRAM) |
| GB (1) | GB2011899B (OSRAM) |
| HU (1) | HU180905B (OSRAM) |
| IT (1) | IT1109011B (OSRAM) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4283536A (en) * | 1977-12-29 | 1981-08-11 | University Of Vermont | Preparation of vincadifformine and related derivatives |
| US4267330A (en) * | 1978-08-24 | 1981-05-12 | Omnium Chimique Societe Anonyme | Process for the synthesis of vincadifformine and related derivatives |
| GB2029828B (en) * | 1978-08-24 | 1983-04-27 | Omnium Chimique Sa | Vincadifformine derivatives |
| US4220774A (en) * | 1978-10-26 | 1980-09-02 | Omnium Chimique | Vincadifformine synthesis process |
| US4428880A (en) | 1981-05-04 | 1984-01-31 | S.A. Omnichem | Azepino[4,5-d]indole derivatives and preparation thereof |
| US4362739A (en) * | 1981-05-04 | 1982-12-07 | S.A. Omnichem | Pyrrolo(2,3-d)carbazole derivatives, compositions and use |
| LU85894A1 (fr) * | 1985-05-10 | 1986-12-05 | Omnichem Sa | Derives de 1,2,3,4,5,6-hexahydro-azepino (4,5-b) indole leur preparation,composes intermediaires,et leur application en therapeutique |
| CO5180550A1 (es) | 1999-04-19 | 2002-07-30 | Smithkline Beecham Corp | Inhibidores de fab i |
| CO5370679A1 (es) * | 1999-06-01 | 2004-02-27 | Smithkline Beecham Corp | Inhibidores fab 1 |
| ECSP003699A (es) * | 1999-10-08 | 2002-04-23 | Smithkline Beecham Corp | Inhibidores de fab i |
| US6762201B1 (en) | 1999-10-08 | 2004-07-13 | Affinium Pharmaceuticals, Inc. | Fab I inhibitors |
| US6730684B1 (en) | 1999-10-08 | 2004-05-04 | Affinium Pharmaceuticals, Inc. | Fab I inhibitors |
| JP4387804B2 (ja) * | 2001-04-06 | 2009-12-24 | アフィニアム・ファーマシューティカルズ・インコーポレイテッド | ＦａｂＩ阻害剤 |
| PT1575951E (pt) * | 2002-12-06 | 2014-09-15 | Debiopharm Int Sa | Compostos heterocíclicos, métodos para os preparar e sua utilização em terapia |
| ATE409485T1 (de) | 2003-03-17 | 2008-10-15 | Affinium Pharm Inc | Pharmazeutische zusammensetzungen inhibitoren von fab i und weitere antibiotika enthaltend |
| PT1828167E (pt) * | 2004-06-04 | 2014-10-08 | Debiopharm Int Sa | Derivados de acrilamida como agentes antibióticos |
| KR20080075027A (ko) * | 2005-12-05 | 2008-08-13 | 아피늄 파마슈티컬스, 인크. | Ｆａｂｉ 억제제 및 항박테리아제로서의헤테로시클릴아크릴아미드 화합물 |
| EP2054422B1 (en) * | 2006-07-20 | 2017-06-14 | Debiopharm International SA | Acrylamide derivatives as fab i inhibitors |
| WO2008098374A1 (en) | 2007-02-16 | 2008-08-21 | Affinium Pharmaceuticals, Inc. | Salts, prodrugs and polymorphs of fab i inhibitors |
| US20130178618A1 (en) | 2012-01-10 | 2013-07-11 | William Allen Boulanger | Novel pharmaceutical intermediates and methods for preparing the same |
| TR201909016T4 (tr) | 2012-06-19 | 2019-07-22 | Debiopharm Int Sa | (E)-n-metil-n-((3-metilbenzofuran-2-il)metil)-3-(7-okso-5,6,7,8-tetrahidro-1,8-naftiridin-3-il)akrilamidin ön ilaç türevleri. |
| RS61312B1 (sr) | 2016-02-26 | 2021-02-26 | Debiopharm Int Sa | Lek za lečenje infekcija dijabetskog stopala |
| CN107216328A (zh) * | 2017-07-06 | 2017-09-29 | 贵州医科大学 | 一种α‑卡波林类化合物的合成方法 |
| TN2021000159A1 (en) | 2019-02-14 | 2023-04-04 | Debiopharm Int Sa | Afabicin formulation, method for making the same and uses thereof |
| MA56184A (fr) | 2019-06-14 | 2022-04-20 | Debiopharm Int Sa | Afabicine pour utilisation dans le traitement d'infections bactériennes impliquant un biofilm |
| US12116372B1 (en) | 2023-12-14 | 2024-10-15 | William Allen Boulanger | Process for preparing methyl 3-bromo-2-(2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)propanoate |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE811614A (en) | 1974-02-27 | 1974-06-17 | (-) Vincadifformine prodn. - by hemisynthesis starting from vindolinine which is obtd. from catharantus roseus |
-
1977
- 1977-12-29 US US05/865,657 patent/US4154943A/en not_active Expired - Lifetime
-
1978
- 1978-12-28 BE BE192612A patent/BE873136A/xx not_active IP Right Cessation
- 1978-12-28 HU HU78OI222A patent/HU180905B/hu not_active IP Right Cessation
- 1978-12-28 CA CA318,789A patent/CA1098903A/en not_active Expired
- 1978-12-29 JP JP16439678A patent/JPS5498800A/ja active Granted
- 1978-12-29 GB GB7850201A patent/GB2011899B/en not_active Expired
- 1978-12-29 FR FR7836935A patent/FR2413391A1/fr active Granted
- 1978-12-29 IT IT09692/78A patent/IT1109011B/it active
- 1978-12-29 ES ES476504A patent/ES476504A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE873136A (fr) | 1979-06-28 |
| GB2011899B (en) | 1982-05-26 |
| HU180905B (en) | 1983-05-30 |
| ES476504A1 (es) | 1979-11-16 |
| FR2413391B1 (OSRAM) | 1983-08-05 |
| CA1098903A (en) | 1981-04-07 |
| GB2011899A (en) | 1979-07-18 |
| JPS6215555B2 (OSRAM) | 1987-04-08 |
| JPS5498800A (en) | 1979-08-03 |
| FR2413391A1 (fr) | 1979-07-27 |
| IT7809692A0 (it) | 1978-12-29 |
| US4154943A (en) | 1979-05-15 |
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