IT1107968B - Derivati n-metilenici sostituiti di tienamicin-solfossido e-solfone - Google Patents
Derivati n-metilenici sostituiti di tienamicin-solfossido e-solfoneInfo
- Publication number
- IT1107968B IT1107968B IT51085/78A IT5108578A IT1107968B IT 1107968 B IT1107968 B IT 1107968B IT 51085/78 A IT51085/78 A IT 51085/78A IT 5108578 A IT5108578 A IT 5108578A IT 1107968 B IT1107968 B IT 1107968B
- Authority
- IT
- Italy
- Prior art keywords
- tienamicin
- sulphone
- sulphoxide
- substituted
- methylene derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/833,619 US4232030A (en) | 1977-09-15 | 1977-09-15 | Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT7851085A0 IT7851085A0 (it) | 1978-09-14 |
| IT1107968B true IT1107968B (it) | 1985-12-02 |
Family
ID=25264884
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT51085/78A IT1107968B (it) | 1977-09-15 | 1978-09-14 | Derivati n-metilenici sostituiti di tienamicin-solfossido e-solfone |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4232030A (it) |
| EP (1) | EP0001264A1 (it) |
| JP (1) | JPS5463097A (it) |
| DK (1) | DK405378A (it) |
| IE (1) | IE47352B1 (it) |
| IT (1) | IT1107968B (it) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4311704A (en) * | 1977-06-03 | 1982-01-19 | Merck & Co., Inc. | Substituted N-methylene derivatives of thienamycin |
| US4335043A (en) * | 1977-11-17 | 1982-06-15 | Merck & Co., Inc. | Substituted N-methylene derivatives of thienamycin |
| DK456580A (da) * | 1979-10-29 | 1981-06-04 | Beecham Group Ltd | Fremgangsmaade til fremstilling af bicycliske beta-lactamringholdige forbindelser |
| JPS5865291A (ja) * | 1981-10-14 | 1983-04-18 | Sankyo Co Ltd | カルバペネム−３−カルボン酸誘導体およびその製法 |
| JPS61236785A (ja) * | 1985-04-15 | 1986-10-22 | Sankyo Co Ltd | アゼチジノン誘導体 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4000129A (en) * | 1970-02-18 | 1976-12-28 | Koninklijke Nederlandsche Gist-En Spiritusfabriek N.V. | 6-aminopenicillanic acid sulfoxide silyl esters |
| US3862181A (en) * | 1970-10-28 | 1975-01-21 | Squibb & Sons Inc | Process for preparing cephalosporins |
| US4022773A (en) * | 1974-08-29 | 1977-05-10 | Toshiyasu Ishimaru | Cephalosporin esters |
| US3950357A (en) * | 1974-11-25 | 1976-04-13 | Merck & Co., Inc. | Antibiotics |
| US4000161A (en) * | 1974-12-19 | 1976-12-28 | Merck & Co., Inc. | Process for purifying thienamycin |
| BE848545A (fr) * | 1975-11-21 | 1977-05-20 | Derives n-methylene substitues de thienamycine, | |
| AU512383B2 (en) * | 1975-11-21 | 1980-10-09 | Merck & Co., Inc. | Thinenamycin derivatives |
| JPS5283992A (en) * | 1976-01-01 | 1977-07-13 | Beecham Group Ltd | Novel antibiotic |
| JPS5283994A (en) * | 1976-01-01 | 1977-07-13 | Beecham Group Ltd | Antibiotic |
| US4172144A (en) * | 1976-10-18 | 1979-10-23 | Merck & Co., Inc. | Schiff's base derivatives of thienamycin |
| US4150145A (en) * | 1977-09-15 | 1979-04-17 | Merck & Co., Inc. | N-alkylated derivatives of thienamycin sulfoxide and sulfone |
-
1977
- 1977-09-15 US US05/833,619 patent/US4232030A/en not_active Expired - Lifetime
-
1978
- 1978-09-14 IT IT51085/78A patent/IT1107968B/it active
- 1978-09-14 JP JP11245278A patent/JPS5463097A/ja active Pending
- 1978-09-14 IE IE1858/78A patent/IE47352B1/en unknown
- 1978-09-14 DK DK405378A patent/DK405378A/da unknown
- 1978-09-15 EP EP78100899A patent/EP0001264A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5463097A (en) | 1979-05-21 |
| US4232030A (en) | 1980-11-04 |
| IE781858L (en) | 1979-03-15 |
| IT7851085A0 (it) | 1978-09-14 |
| DK405378A (da) | 1979-03-16 |
| EP0001264A1 (en) | 1979-04-04 |
| IE47352B1 (en) | 1984-02-22 |
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