IT1105091B - HETEROCYCLIC COMPOSITS OF THE INDOLO SERIES WITH PHARMACEUTICAL USE AND PROCEDURE FOR THEIR PRODUCTION - Google Patents

HETEROCYCLIC COMPOSITS OF THE INDOLO SERIES WITH PHARMACEUTICAL USE AND PROCEDURE FOR THEIR PRODUCTION

Info

Publication number
IT1105091B
IT1105091B IT50228/78A IT5022878A IT1105091B IT 1105091 B IT1105091 B IT 1105091B IT 50228/78 A IT50228/78 A IT 50228/78A IT 5022878 A IT5022878 A IT 5022878A IT 1105091 B IT1105091 B IT 1105091B
Authority
IT
Italy
Prior art keywords
composits
indolo
heterocyclic
procedure
series
Prior art date
Application number
IT50228/78A
Other languages
Italian (it)
Other versions
IT7850228A0 (en
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IT7850228A0 publication Critical patent/IT7850228A0/en
Application granted granted Critical
Publication of IT1105091B publication Critical patent/IT1105091B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IT50228/78A 1977-07-13 1978-07-10 HETEROCYCLIC COMPOSITS OF THE INDOLO SERIES WITH PHARMACEUTICAL USE AND PROCEDURE FOR THEIR PRODUCTION IT1105091B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81513877A 1977-07-13 1977-07-13

Publications (2)

Publication Number Publication Date
IT7850228A0 IT7850228A0 (en) 1978-07-10
IT1105091B true IT1105091B (en) 1985-10-28

Family

ID=25216976

Family Applications (1)

Application Number Title Priority Date Filing Date
IT50228/78A IT1105091B (en) 1977-07-13 1978-07-10 HETEROCYCLIC COMPOSITS OF THE INDOLO SERIES WITH PHARMACEUTICAL USE AND PROCEDURE FOR THEIR PRODUCTION

Country Status (30)

Country Link
JP (1) JPS5419972A (en)
AR (1) AR225274A1 (en)
AT (1) AT364821B (en)
AU (1) AU525064B2 (en)
BE (1) BE868943A (en)
CA (1) CA1116598A (en)
CH (1) CH642066A5 (en)
CY (1) CY1274A (en)
DE (1) DE2830884A1 (en)
DK (1) DK156568C (en)
ES (1) ES471674A1 (en)
FI (1) FI69835C (en)
FR (1) FR2397404A1 (en)
GB (1) GB2001633B (en)
GR (1) GR74488B (en)
HK (1) HK1385A (en)
HU (1) HU178992B (en)
IE (1) IE47122B1 (en)
IL (1) IL55115A (en)
IT (1) IT1105091B (en)
KE (1) KE3485A (en)
LU (1) LU79966A1 (en)
MY (1) MY8500946A (en)
NL (1) NL189946C (en)
NO (1) NO149311C (en)
NZ (1) NZ187763A (en)
SE (1) SE429339B (en)
SG (1) SG82584G (en)
YU (1) YU40528B (en)
ZA (1) ZA783744B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2463765A1 (en) * 1979-08-17 1981-02-27 Clin Midy NEW ACTIVE INDOLE DERIVATIVES ON THE CARDIOVASCULAR SYSTEM
US4321398A (en) * 1981-05-07 1982-03-23 Mead Johnson & Company Thienyl and benzothienyl-tertiary butylaminophenoxypropanols
DE3119796A1 (en) * 1981-05-19 1982-12-23 Hoechst Ag, 6000 Frankfurt SUBSTITUTED TRYPTAMINE DERIVATIVES OF THIENYLOX PROPANOLAMINES, METHODS FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS AND THEIR USE
FR2523964B1 (en) * 1982-03-23 1985-09-27 Sanofi Sa NOVEL TRYPTAMINE DERIVATIVES ACTIVE IN PARTICULAR ON THE CARDIOVASCULAR SYSTEM AND PROCESS FOR THEIR PREPARATION
NZ208337A (en) * 1983-06-10 1988-10-28 Bristol Myers Co 2-(2-hydroxy-3-((2-(ar-hydroxy-1h-aminopropoxy-yl)ethyl benzonitriles and pharmaceutical compositions
FR2601008B1 (en) * 1986-07-03 1990-03-30 Sanofi Sa PROCESS FOR THE STEREOSPECIFIC SYNTHESIS OF INDOLE DERIVATIVES
US6825220B2 (en) 2000-11-10 2004-11-30 Eli Lilly And Company 3-Substituted oxindole β 3 agonists
WO2003016307A1 (en) * 2001-08-14 2003-02-27 Eli Lilly And Company β3 ADRENERGIC AGONISTS
DE60211199T2 (en) 2001-08-14 2007-02-01 Eli Lilly And Co., Indianapolis 3-SUBSTITUTED OXINDOL BETA-3 AGONISTS
JP2005518357A (en) 2001-11-20 2005-06-23 イーライ・リリー・アンド・カンパニー Beta 3 adrenergic agonist
JP2005514366A (en) 2001-11-20 2005-05-19 イーライ・リリー・アンド・カンパニー 3-Substituted oxindole β3 agonist
EP1467733A1 (en) 2002-01-11 2004-10-20 Eli Lilly And Company 2-oxo-benzimidazolyl substituted ethanolamine derivatives and their use as beta3 agonists
CA2732513C (en) 2008-08-01 2017-04-25 Arca Biopharma, Inc. Methods and compositions involving (s)-bucindolol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1532210A (en) * 1963-06-21 1968-07-12 Ici Ltd Heterocyclic compounds and their preparation process
CH495983A (en) * 1968-02-09 1970-09-15 Sandoz Ag Process for the preparation of levorotatory 4- (2-hydroxy-3-isopropylaminopropoxy) indole
US3371098A (en) * 1966-11-29 1968-02-27 Philips Corp 5- and 6-methoxy-3-(phenoxyethyl-aminoethyl)-indoles
US3946009A (en) * 1972-05-05 1976-03-23 Merck Sharp & Dohme (I.A.) Corporation 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazines

Also Published As

Publication number Publication date
YU161178A (en) 1983-02-28
ES471674A1 (en) 1979-10-01
DE2830884C2 (en) 1990-01-11
IE781400L (en) 1979-01-13
JPS5419972A (en) 1979-02-15
IT7850228A0 (en) 1978-07-10
NL189946B (en) 1993-04-16
SG82584G (en) 1985-09-13
KE3485A (en) 1985-01-25
DK313878A (en) 1979-01-14
AU525064B2 (en) 1982-10-21
GB2001633B (en) 1982-03-24
NL7807564A (en) 1979-01-16
FR2397404B1 (en) 1982-06-11
IL55115A (en) 1981-09-13
DK156568C (en) 1990-02-05
ATA508978A (en) 1981-04-15
AT364821B (en) 1981-11-25
AR225274A1 (en) 1982-03-15
DE2830884A1 (en) 1979-02-01
AU3770478A (en) 1980-01-10
NL189946C (en) 1993-09-16
GR74488B (en) 1984-06-28
ZA783744B (en) 1979-07-25
NZ187763A (en) 1984-07-31
YU40528B (en) 1986-02-28
FI782205A (en) 1979-01-14
HU178992B (en) 1982-07-28
FR2397404A1 (en) 1979-02-09
GB2001633A (en) 1979-02-07
SE7807700L (en) 1979-01-14
NO149311B (en) 1983-12-19
NO782407L (en) 1979-01-16
IL55115A0 (en) 1978-09-29
JPS6340784B2 (en) 1988-08-12
FI69835B (en) 1985-12-31
MY8500946A (en) 1985-12-31
CH642066A5 (en) 1984-03-30
HK1385A (en) 1985-01-11
CY1274A (en) 1985-03-08
IE47122B1 (en) 1983-12-28
LU79966A1 (en) 1979-04-09
CA1116598A (en) 1982-01-19
SE429339B (en) 1983-08-29
FI69835C (en) 1986-05-26
NO149311C (en) 1984-03-28
DK156568B (en) 1989-09-11
BE868943A (en) 1979-01-12

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970730