ATA508978A - METHOD FOR PRODUCING NEW INDOLES, THEIR ACID ADDITION SALTS AND THE ISOMERS THEREOF - Google Patents

METHOD FOR PRODUCING NEW INDOLES, THEIR ACID ADDITION SALTS AND THE ISOMERS THEREOF

Info

Publication number
ATA508978A
ATA508978A AT508978A AT508978A ATA508978A AT A508978 A ATA508978 A AT A508978A AT 508978 A AT508978 A AT 508978A AT 508978 A AT508978 A AT 508978A AT A508978 A ATA508978 A AT A508978A
Authority
AT
Austria
Prior art keywords
isomers
acid addition
addition salts
producing new
new indoles
Prior art date
Application number
AT508978A
Other languages
German (de)
Other versions
AT364821B (en
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ATA508978A publication Critical patent/ATA508978A/en
Application granted granted Critical
Publication of AT364821B publication Critical patent/AT364821B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
AT0508978A 1977-07-13 1978-07-13 METHOD FOR PRODUCING NEW INDOLES, THEIR ACID ADDITION SALTS AND THE ISOMERS THEREOF AT364821B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81513877A 1977-07-13 1977-07-13

Publications (2)

Publication Number Publication Date
ATA508978A true ATA508978A (en) 1981-04-15
AT364821B AT364821B (en) 1981-11-25

Family

ID=25216976

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0508978A AT364821B (en) 1977-07-13 1978-07-13 METHOD FOR PRODUCING NEW INDOLES, THEIR ACID ADDITION SALTS AND THE ISOMERS THEREOF

Country Status (30)

Country Link
JP (1) JPS5419972A (en)
AR (1) AR225274A1 (en)
AT (1) AT364821B (en)
AU (1) AU525064B2 (en)
BE (1) BE868943A (en)
CA (1) CA1116598A (en)
CH (1) CH642066A5 (en)
CY (1) CY1274A (en)
DE (1) DE2830884A1 (en)
DK (1) DK156568C (en)
ES (1) ES471674A1 (en)
FI (1) FI69835C (en)
FR (1) FR2397404A1 (en)
GB (1) GB2001633B (en)
GR (1) GR74488B (en)
HK (1) HK1385A (en)
HU (1) HU178992B (en)
IE (1) IE47122B1 (en)
IL (1) IL55115A (en)
IT (1) IT1105091B (en)
KE (1) KE3485A (en)
LU (1) LU79966A1 (en)
MY (1) MY8500946A (en)
NL (1) NL189946C (en)
NO (1) NO149311C (en)
NZ (1) NZ187763A (en)
SE (1) SE429339B (en)
SG (1) SG82584G (en)
YU (1) YU40528B (en)
ZA (1) ZA783744B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2463765A1 (en) * 1979-08-17 1981-02-27 Clin Midy NEW ACTIVE INDOLE DERIVATIVES ON THE CARDIOVASCULAR SYSTEM
US4321398A (en) * 1981-05-07 1982-03-23 Mead Johnson & Company Thienyl and benzothienyl-tertiary butylaminophenoxypropanols
DE3119796A1 (en) * 1981-05-19 1982-12-23 Hoechst Ag, 6000 Frankfurt SUBSTITUTED TRYPTAMINE DERIVATIVES OF THIENYLOX PROPANOLAMINES, METHODS FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS AND THEIR USE
FR2523964B1 (en) * 1982-03-23 1985-09-27 Sanofi Sa NOVEL TRYPTAMINE DERIVATIVES ACTIVE IN PARTICULAR ON THE CARDIOVASCULAR SYSTEM AND PROCESS FOR THEIR PREPARATION
NZ208337A (en) * 1983-06-10 1988-10-28 Bristol Myers Co 2-(2-hydroxy-3-((2-(ar-hydroxy-1h-aminopropoxy-yl)ethyl benzonitriles and pharmaceutical compositions
FR2601008B1 (en) * 1986-07-03 1990-03-30 Sanofi Sa PROCESS FOR THE STEREOSPECIFIC SYNTHESIS OF INDOLE DERIVATIVES
DE60120748T2 (en) 2000-11-10 2007-05-16 Eli Lilly And Co., Indianapolis 3-SUBSTITUTED OXINDOLE DERIVATIVES AS BETA-3 AGONISTS
EP1421078B1 (en) 2001-08-14 2006-09-27 Eli Lilly And Company Indole derivatives as beta-3 adrenergic agonists for the treatment of type 2 diabetes
EP1444224B1 (en) 2001-08-14 2006-05-03 Eli Lilly And Company 3-substituted oxindole beta-3 agonists
AU2002353844A1 (en) 2001-11-20 2003-06-10 Eli Lilly And Company Beta 3 adrenergic agonists
AU2002347982A1 (en) 2001-11-20 2003-06-10 Eli Lilly And Company 3-SUBSTITUTED OXINDOLE Beta3 AGONISTS
US7009060B2 (en) 2002-01-11 2006-03-07 Eli Lilly And Company 2-oxo-benzimidazolyl substituted ethanolamine derivatives and their use as β3 agonists
CA2732513C (en) 2008-08-01 2017-04-25 Arca Biopharma, Inc. Methods and compositions involving (s)-bucindolol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1532210A (en) * 1963-06-21 1968-07-12 Ici Ltd Heterocyclic compounds and their preparation process
CH495983A (en) * 1968-02-09 1970-09-15 Sandoz Ag Process for the preparation of levorotatory 4- (2-hydroxy-3-isopropylaminopropoxy) indole
US3371098A (en) * 1966-11-29 1968-02-27 Philips Corp 5- and 6-methoxy-3-(phenoxyethyl-aminoethyl)-indoles
US3946009A (en) * 1972-05-05 1976-03-23 Merck Sharp & Dohme (I.A.) Corporation 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazines

Also Published As

Publication number Publication date
IT1105091B (en) 1985-10-28
DK156568B (en) 1989-09-11
AU3770478A (en) 1980-01-10
NO782407L (en) 1979-01-16
JPS6340784B2 (en) 1988-08-12
IL55115A (en) 1981-09-13
FR2397404B1 (en) 1982-06-11
NL189946C (en) 1993-09-16
FR2397404A1 (en) 1979-02-09
GB2001633A (en) 1979-02-07
YU161178A (en) 1983-02-28
IL55115A0 (en) 1978-09-29
CH642066A5 (en) 1984-03-30
ZA783744B (en) 1979-07-25
FI782205A (en) 1979-01-14
KE3485A (en) 1985-01-25
HU178992B (en) 1982-07-28
NL189946B (en) 1993-04-16
SG82584G (en) 1985-09-13
ES471674A1 (en) 1979-10-01
AU525064B2 (en) 1982-10-21
YU40528B (en) 1986-02-28
GR74488B (en) 1984-06-28
CY1274A (en) 1985-03-08
DE2830884C2 (en) 1990-01-11
AT364821B (en) 1981-11-25
IE47122B1 (en) 1983-12-28
NZ187763A (en) 1984-07-31
NL7807564A (en) 1979-01-16
SE7807700L (en) 1979-01-14
DK156568C (en) 1990-02-05
JPS5419972A (en) 1979-02-15
NO149311C (en) 1984-03-28
MY8500946A (en) 1985-12-31
GB2001633B (en) 1982-03-24
NO149311B (en) 1983-12-19
FI69835C (en) 1986-05-26
DE2830884A1 (en) 1979-02-01
IE781400L (en) 1979-01-13
IT7850228A0 (en) 1978-07-10
HK1385A (en) 1985-01-11
AR225274A1 (en) 1982-03-15
LU79966A1 (en) 1979-04-09
SE429339B (en) 1983-08-29
DK313878A (en) 1979-01-14
BE868943A (en) 1979-01-12
FI69835B (en) 1985-12-31
CA1116598A (en) 1982-01-19

Similar Documents

Publication Publication Date Title
AT365581B (en) METHOD FOR PRODUCING NEW 2-BENZYL-1,2DIHYDRO-1-OXO-PHTHALAZINE-4-YLESSIGAIC DERIVATIVES AND THE SALTS THEREOF
AT365589B (en) METHOD FOR PRODUCING NEW 4-HYDROXY-2H-1,2BENZOTHIAZINE-3-CARBOXAMIDE-1,1-DIOXIDE AND THE SALTS THEREOF
AT365187B (en) METHOD FOR PRODUCING NEW 3- (1H-TETRAZOL-5YL) -HH-PYRIDO (1,2-A) -PYRIMIDIN-4-ONE AND THEIR SALTS
ATA936176A (en) METHOD FOR PRODUCING NEW, BASICLY SUBSTITUTED INDOLDER DERIVATIVES AND THEIR ACID ADDITION SALTS
AT364821B (en) METHOD FOR PRODUCING NEW INDOLES, THEIR ACID ADDITION SALTS AND THE ISOMERS THEREOF
AT377254B (en) METHOD FOR PRODUCING NEW SUBSTITUTED PYRROLIDINS AND THEIR SALTS
AT361929B (en) METHOD FOR PRODUCING NEW 5,11-DIHYDRO- 6H-PYRIDO (2,3-B) (1,4) BENZODIAZEPINE-6-ON DERIVATIVES AND THEIR SALTS
AT380020B (en) METHOD FOR PRODUCING D, 1-5-METHYLTETRAHYDROFOLS | UREAND THE SALTS
DD132964A5 (en) PROCESS FOR PREPARING NEW SUBSTITUTED 2-PHENYLAMINO-IMIDAZOLINE- (2) AND THE SAEUREADDITIONAL SALT
ATA863478A (en) METHOD FOR PRODUCING NEW 1,4-BENZODIAZEPINE DERIVATIVES AND THEIR SALTS
AT360028B (en) METHOD FOR PRODUCING NEW, 5-PIPERAZINYL-SUBSTITUTED DERIVATIVES OF PYRIDO- (2.3-B) - -BENZOTHIAZEPINE (1.5) AND THEIR SALTS
AT357517B (en) METHOD FOR PRODUCING NEW SUBSTITUTED INDOLES AND THEIR ACID ADDITION SALTS
AT367022B (en) METHOD FOR PRODUCING NEW SUBSTITUTED AETHANOLAMINS AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS
AT375938B (en) METHOD FOR PRODUCING 9-AMINO-6,7-DIHYDRO-4H-PYRIDO (1,2-A) PYRIMIDIN-4-ON DERIVATIVES, THEIR PHYSIOLOGICALLY COMPATIBLE SALTS, HYDRATES AND ISOMERS
AT369738B (en) METHOD FOR PRODUCING NEW THIODIBENZOXEPINES AND THEIR ACID ADDITION SALTS
ATA407977A (en) METHOD FOR PRODUCING NEW HYDRAZINOPYRIDAZINE DERIVATIVES AND THEIR SALTS
ATA525878A (en) METHOD FOR PRODUCING NEW INDOLES AND THEIR SALTS
AT357516B (en) METHOD FOR PRODUCING NEW 2,3-DIHYDRO-BENZOFURANONE-2 DERIVATIVES
AT351529B (en) METHOD FOR PRODUCING NEW 1,2,4-TRIAZOLE DERIVATIVES AND THEIR ACID ADDITION SALTS
AT361916B (en) METHOD FOR PRODUCING NEW 3-IMINO-9.9A DIHYDROTHIAZOLO (3,4-A) INDOLE DERIVATIVES AND THEIR SALTS
AT357519B (en) METHOD FOR PRODUCING NEW, BASICLY SUBSTITUTED INDOLDER DERIVATIVES AND THEIR ACID ADDITION SALTS
AT365606B (en) METHOD FOR PRODUCING NEW 1,6-ANHYDRO-BETA-D-HEXOPYRANOSE DERIVATIVES
AT360040B (en) METHOD FOR THE PRODUCTION OF SUBSTITUTED OROTSAEUREN, DIHYDROOROTAEUREN AND THEIR SALTS
AT371115B (en) METHOD FOR PRODUCING NEW 1,2,3,4-TETRAHYDRO-2-PIPERAZINYL NAPHTHALINE AND ITS ACID ADDITION SALTS
ATA576279A (en) PROCESS FOR PRODUCING NEW BASIC SUBSTITUTE INDOLDER DERIVATIVES AND THEIR ACID ADDITIONAL SALTS

Legal Events

Date Code Title Description
ELA Expired due to lapse of time