IT1104556B - Salt of lysine with meta-benzoyl-hydratropic acid - used as non-ulcerogenic antiinflammatory, analgesic and anti-agglutinant - Google Patents

Salt of lysine with meta-benzoyl-hydratropic acid - used as non-ulcerogenic antiinflammatory, analgesic and anti-agglutinant

Info

Publication number
IT1104556B
IT1104556B IT2346577A IT2346577A IT1104556B IT 1104556 B IT1104556 B IT 1104556B IT 2346577 A IT2346577 A IT 2346577A IT 2346577 A IT2346577 A IT 2346577A IT 1104556 B IT1104556 B IT 1104556B
Authority
IT
Italy
Prior art keywords
benzoyl
lysine
ulcerogenic
analgesic
salt
Prior art date
Application number
IT2346577A
Other languages
Italian (it)
Inventor
Giuseppe Quadro
Original Assignee
Medea Res Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medea Res Srl filed Critical Medea Res Srl
Priority to IT2346577A priority Critical patent/IT1104556B/en
Priority to BE0/200306A priority patent/BE882889A/en
Application granted granted Critical
Publication of IT1104556B publication Critical patent/IT1104556B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Lysine m-benzoyl hydratropic acid salt of formula (I) is new. Used as anti-inflammatory analgesic, and anti-agglutiant. (I) is free from the ulcerogenic properties of m-benzoyl hydratropic acid (II) itself. Equimolar amts. of (II) and lysine are mixed in an alcoholic or aq. alcoholic medium, and (I) is sepd. by concn. of by pptn. with a non-solvent.
IT2346577A 1977-05-12 1977-05-12 Salt of lysine with meta-benzoyl-hydratropic acid - used as non-ulcerogenic antiinflammatory, analgesic and anti-agglutinant IT1104556B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IT2346577A IT1104556B (en) 1977-05-12 1977-05-12 Salt of lysine with meta-benzoyl-hydratropic acid - used as non-ulcerogenic antiinflammatory, analgesic and anti-agglutinant
BE0/200306A BE882889A (en) 1977-05-12 1980-04-21 LYSINE SALT OF META-BENZOYL-HYDRATROPIC ACID, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2346577A IT1104556B (en) 1977-05-12 1977-05-12 Salt of lysine with meta-benzoyl-hydratropic acid - used as non-ulcerogenic antiinflammatory, analgesic and anti-agglutinant

Publications (1)

Publication Number Publication Date
IT1104556B true IT1104556B (en) 1985-10-21

Family

ID=11207332

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2346577A IT1104556B (en) 1977-05-12 1977-05-12 Salt of lysine with meta-benzoyl-hydratropic acid - used as non-ulcerogenic antiinflammatory, analgesic and anti-agglutinant

Country Status (2)

Country Link
BE (1) BE882889A (en)
IT (1) IT1104556B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3328401A1 (en) * 1983-08-05 1985-02-21 Merckle GmbH, 7902 Blaubeuren INJECTABLE SOLUTION FOR TREATING INFLAMMATION
IT1247138B (en) * 1991-03-06 1994-12-12 Dompe Farmaceutici Spa HYDROPHILE PHARMACEUTICAL COMPOSITION CONTAINING KETOPROFENE LYSINE SALT FOR TOPICAL USE.
US5808069A (en) * 1993-03-09 1998-09-15 Dompe' Farmaceutici Spa Salts of 2-(3-benzoylphenyl) propionic acid with organic bases and pharmaceutical compositions thereof
EP3670489A1 (en) * 2018-12-21 2020-06-24 Dompé farmaceutici S.p.A. Co-crystal of ketoprofen, compositions comprising the same, process of producing the same, and uses thereof
EP3842408A1 (en) * 2019-12-23 2021-06-30 Dompé farmaceutici S.p.A. Co-crystal of ketoprofen and its preparation, pharmaceutical compositions comprising the same and uses thereof
EP3900715A1 (en) * 2020-04-21 2021-10-27 Dompe' Farmaceutici S.P.A. Synergistic admixtures of gabapentin and ketoprofen, pharmaceutical compositions and their medical use
EP3900716A1 (en) 2020-04-21 2021-10-27 Dompe' Farmaceutici S.P.A. Co-crystal of gabapentin, ketoprofen and lysine, pharmaceutical compositions and their medical use
EP3907214A1 (en) 2020-05-04 2021-11-10 Dompe' Farmaceutici S.P.A. Co-crystal of ketoprofen, lysine and gabapentin, pharmaceutical compositions and their medical use

Also Published As

Publication number Publication date
BE882889A (en) 1980-08-18

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Legal Events

Date Code Title Description
ITCP Complementary protection certificate

Free format text: CCP 17

MEDD Supplementary protection certificate for pharmaceutical products: granted

Free format text: CCP 17, 19920117; DOMPE' FARMACEUTICI S.P.A.

TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970529