IT1085033B - Procedimento per la preparazione di metossi-psorali - Google Patents

Procedimento per la preparazione di metossi-psorali

Info

Publication number
IT1085033B
IT1085033B IT27148/77A IT2714877A IT1085033B IT 1085033 B IT1085033 B IT 1085033B IT 27148/77 A IT27148/77 A IT 27148/77A IT 2714877 A IT2714877 A IT 2714877A IT 1085033 B IT1085033 B IT 1085033B
Authority
IT
Italy
Prior art keywords
psorali
metossi
procedure
preparation
Prior art date
Application number
IT27148/77A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of IT1085033B publication Critical patent/IT1085033B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
IT27148/77A 1976-09-14 1977-08-31 Procedimento per la preparazione di metossi-psorali IT1085033B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72311676A 1976-09-14 1976-09-14

Publications (1)

Publication Number Publication Date
IT1085033B true IT1085033B (it) 1985-05-28

Family

ID=24904922

Family Applications (1)

Application Number Title Priority Date Filing Date
IT27148/77A IT1085033B (it) 1976-09-14 1977-08-31 Procedimento per la preparazione di metossi-psorali

Country Status (7)

Country Link
US (1) US4130568A (it)
JP (1) JPS5337694A (it)
BE (1) BE858640A (it)
DE (1) DE2741233A1 (it)
FR (1) FR2368488A1 (it)
IT (1) IT1085033B (it)
NL (1) NL7709748A (it)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4169204A (en) * 1976-10-20 1979-09-25 Regents Of The University Of California Psoralens
US5360816A (en) * 1977-05-05 1994-11-01 Goupil Jean Jacques 5-methoxy psoralen used to treat psoriasis
LU80347A1 (fr) 1977-10-21 1979-03-16 Goupil J 5-methoxy-psoralene comme nouveau medicament et procede de synthese
SE445422B (sv) * 1979-06-25 1986-06-23 Gerot Pharmazeutika Farmaceutisk beredning for oral administereing innehallande 8-metoxi-furo-/3',2':6,7/-kumarin
US4370344A (en) * 1979-09-10 1983-01-25 Elder Pharmaceuticals, Inc. 5'-Aminoalkyl-4'-alkylpsoralens
US4298614A (en) * 1979-09-10 1981-11-03 Thomas C. Elder, Inc. 5'-Aminoalkyl-4',4-dialkylpsoralens
US4454152A (en) * 1980-05-07 1984-06-12 Hoffmann-La Roche Inc. Methoxsalen dosage forms
US5356929A (en) * 1989-01-23 1994-10-18 Lehigh University Reduced and quaternized psoralens as photo-activated therapeutics
FR2695036B1 (fr) * 1992-09-03 1994-10-28 Goupil Jean Jacques Huile contenant du 5-méthoxypsoralène à une concentration de 60 à 100 PPM et son utilisation pour le traitement du psoriasis.
US6255324B1 (en) 1998-11-25 2001-07-03 Ned D. Heindel Amino-and mercurio-substituted 4′,5'-dihydropsoralens and therapeutical uses thereof
CA2352258A1 (en) 1998-11-30 2000-06-08 Jeffrey D. Laskin 4'-substituted-4',5'-dihydropsoralens and therapeutical uses thereof
US8071642B2 (en) * 2007-06-28 2011-12-06 Rutgers, The State University Of New Jersey Dimethyl amino ethyl ether psoralens and methods for their production and use
FR3018813B1 (fr) 2014-03-18 2016-04-15 Maco Pharma Sa Procede de synthese d'un derive de psoralene
CN107814784A (zh) * 2017-02-24 2018-03-20 厦门大学 一种咖啡酸内酯及其制备方法、药物组合物与应用
CN112062773B (zh) * 2019-06-11 2021-11-26 中国科学院大连化学物理研究所 一种酸催化4-羟基香豆素与异戊二烯环化反应的方法
CN116554191B (zh) * 2023-05-06 2025-12-05 河南中烟工业有限责任公司 一种香柑内酯的合成方法
CN119409706B (zh) * 2024-10-30 2025-12-19 中国科学院新疆理化技术研究所 一种无花果果实中的呋喃香豆素类对映异构体及其制备方法和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3244729A (en) * 1966-04-05 Dimethoxy-x-methyl-g,y-furanocou- marin compounds
US2889337A (en) * 1956-07-19 1959-06-02 William L Stanley Isolation of furocoumarins
US3201421A (en) * 1962-05-09 1965-08-17 Dept Of Chemistry Preparation of alkyl psoralens
US3553236A (en) * 1968-12-06 1971-01-05 Franco Indian Pharmaceuticals Psoralene and isopsoralene, process for their isolation and separation

Also Published As

Publication number Publication date
US4130568A (en) 1978-12-19
FR2368488A1 (fr) 1978-05-19
JPS5337694A (en) 1978-04-06
BE858640A (fr) 1978-03-13
NL7709748A (nl) 1978-03-16
DE2741233A1 (de) 1978-03-16

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