JPS5337694A - Production of 88 methoxypusolalene derivative and novel intermediate to produce same - Google Patents

Production of 88 methoxypusolalene derivative and novel intermediate to produce same

Info

Publication number
JPS5337694A
JPS5337694A JP10955777A JP10955777A JPS5337694A JP S5337694 A JPS5337694 A JP S5337694A JP 10955777 A JP10955777 A JP 10955777A JP 10955777 A JP10955777 A JP 10955777A JP S5337694 A JPS5337694 A JP S5337694A
Authority
JP
Japan
Prior art keywords
methoxypusolalene
derivative
production
novel intermediate
produce same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10955777A
Other languages
English (en)
Inventor
Nikorasu Konfuaron Pasukuooru
Daian Rooraa Erizabesu
Pizorato Jiyakomo
Radojie Usukokobitsuku Miran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JPS5337694A publication Critical patent/JPS5337694A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP10955777A 1976-09-14 1977-09-13 Production of 88 methoxypusolalene derivative and novel intermediate to produce same Pending JPS5337694A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72311676A 1976-09-14 1976-09-14

Publications (1)

Publication Number Publication Date
JPS5337694A true JPS5337694A (en) 1978-04-06

Family

ID=24904922

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10955777A Pending JPS5337694A (en) 1976-09-14 1977-09-13 Production of 88 methoxypusolalene derivative and novel intermediate to produce same

Country Status (7)

Country Link
US (1) US4130568A (ja)
JP (1) JPS5337694A (ja)
BE (1) BE858640A (ja)
DE (1) DE2741233A1 (ja)
FR (1) FR2368488A1 (ja)
IT (1) IT1085033B (ja)
NL (1) NL7709748A (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112062773A (zh) * 2019-06-11 2020-12-11 中国科学院大连化学物理研究所 一种酸催化4-羟基香豆素与异戊二烯环化反应的方法

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4169204A (en) * 1976-10-20 1979-09-25 Regents Of The University Of California Psoralens
US5360816A (en) * 1977-05-05 1994-11-01 Goupil Jean Jacques 5-methoxy psoralen used to treat psoriasis
LU80347A1 (fr) 1977-10-21 1979-03-16 Goupil J 5-methoxy-psoralene comme nouveau medicament et procede de synthese
SE445422B (sv) * 1979-06-25 1986-06-23 Gerot Pharmazeutika Farmaceutisk beredning for oral administereing innehallande 8-metoxi-furo-/3',2':6,7/-kumarin
US4298614A (en) * 1979-09-10 1981-11-03 Thomas C. Elder, Inc. 5'-Aminoalkyl-4',4-dialkylpsoralens
US4370344A (en) * 1979-09-10 1983-01-25 Elder Pharmaceuticals, Inc. 5'-Aminoalkyl-4'-alkylpsoralens
US4454152A (en) * 1980-05-07 1984-06-12 Hoffmann-La Roche Inc. Methoxsalen dosage forms
US5356929A (en) * 1989-01-23 1994-10-18 Lehigh University Reduced and quaternized psoralens as photo-activated therapeutics
FR2695036B1 (fr) * 1992-09-03 1994-10-28 Goupil Jean Jacques Huile contenant du 5-méthoxypsoralène à une concentration de 60 à 100 PPM et son utilisation pour le traitement du psoriasis.
US6255324B1 (en) 1998-11-25 2001-07-03 Ned D. Heindel Amino-and mercurio-substituted 4′,5'-dihydropsoralens and therapeutical uses thereof
WO2000032603A1 (en) 1998-11-30 2000-06-08 Buckman Laboratories International, Inc. 4'-substituted-4',5'-dihydropsoralens and therapeutical uses thereof
US8071642B2 (en) * 2007-06-28 2011-12-06 Rutgers, The State University Of New Jersey Dimethyl amino ethyl ether psoralens and methods for their production and use
FR3018813B1 (fr) 2014-03-18 2016-04-15 Maco Pharma Sa Procede de synthese d'un derive de psoralene
CN107814784A (zh) * 2017-02-24 2018-03-20 厦门大学 一种咖啡酸内酯及其制备方法、药物组合物与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3244729A (en) * 1966-04-05 Dimethoxy-x-methyl-g,y-furanocou- marin compounds
US2889337A (en) * 1956-07-19 1959-06-02 William L Stanley Isolation of furocoumarins
US3201421A (en) * 1962-05-09 1965-08-17 Dept Of Chemistry Preparation of alkyl psoralens
US3553236A (en) * 1968-12-06 1971-01-05 Franco Indian Pharmaceuticals Psoralene and isopsoralene, process for their isolation and separation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112062773A (zh) * 2019-06-11 2020-12-11 中国科学院大连化学物理研究所 一种酸催化4-羟基香豆素与异戊二烯环化反应的方法

Also Published As

Publication number Publication date
DE2741233A1 (de) 1978-03-16
NL7709748A (nl) 1978-03-16
BE858640A (fr) 1978-03-13
IT1085033B (it) 1985-05-28
US4130568A (en) 1978-12-19
FR2368488A1 (fr) 1978-05-19

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