BE858640A - Procede pour la preparation de methoxypsoralene - Google Patents

Procede pour la preparation de methoxypsoralene

Info

Publication number
BE858640A
BE858640A BE180857A BE180857A BE858640A BE 858640 A BE858640 A BE 858640A BE 180857 A BE180857 A BE 180857A BE 180857 A BE180857 A BE 180857A BE 858640 A BE858640 A BE 858640A
Authority
BE
Belgium
Prior art keywords
methoxypsoralene
preparation
Prior art date
Application number
BE180857A
Other languages
English (en)
French (fr)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BE858640A publication Critical patent/BE858640A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BE180857A 1976-09-14 1977-09-13 Procede pour la preparation de methoxypsoralene BE858640A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72311676A 1976-09-14 1976-09-14

Publications (1)

Publication Number Publication Date
BE858640A true BE858640A (fr) 1978-03-13

Family

ID=24904922

Family Applications (1)

Application Number Title Priority Date Filing Date
BE180857A BE858640A (fr) 1976-09-14 1977-09-13 Procede pour la preparation de methoxypsoralene

Country Status (7)

Country Link
US (1) US4130568A (xx)
JP (1) JPS5337694A (xx)
BE (1) BE858640A (xx)
DE (1) DE2741233A1 (xx)
FR (1) FR2368488A1 (xx)
IT (1) IT1085033B (xx)
NL (1) NL7709748A (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4169204A (en) * 1976-10-20 1979-09-25 Regents Of The University Of California Psoralens
US5360816A (en) * 1977-05-05 1994-11-01 Goupil Jean Jacques 5-methoxy psoralen used to treat psoriasis
LU80347A1 (fr) 1977-10-21 1979-03-16 Goupil J 5-methoxy-psoralene comme nouveau medicament et procede de synthese
SE445422B (sv) * 1979-06-25 1986-06-23 Gerot Pharmazeutika Farmaceutisk beredning for oral administereing innehallande 8-metoxi-furo-/3',2':6,7/-kumarin
US4298614A (en) * 1979-09-10 1981-11-03 Thomas C. Elder, Inc. 5'-Aminoalkyl-4',4-dialkylpsoralens
US4370344A (en) * 1979-09-10 1983-01-25 Elder Pharmaceuticals, Inc. 5'-Aminoalkyl-4'-alkylpsoralens
US4454152A (en) * 1980-05-07 1984-06-12 Hoffmann-La Roche Inc. Methoxsalen dosage forms
US5356929A (en) * 1989-01-23 1994-10-18 Lehigh University Reduced and quaternized psoralens as photo-activated therapeutics
FR2695036B1 (fr) * 1992-09-03 1994-10-28 Goupil Jean Jacques Huile contenant du 5-méthoxypsoralène à une concentration de 60 à 100 PPM et son utilisation pour le traitement du psoriasis.
US6255324B1 (en) 1998-11-25 2001-07-03 Ned D. Heindel Amino-and mercurio-substituted 4′,5'-dihydropsoralens and therapeutical uses thereof
WO2000032603A1 (en) 1998-11-30 2000-06-08 Buckman Laboratories International, Inc. 4'-substituted-4',5'-dihydropsoralens and therapeutical uses thereof
US8071642B2 (en) * 2007-06-28 2011-12-06 Rutgers, The State University Of New Jersey Dimethyl amino ethyl ether psoralens and methods for their production and use
FR3018813B1 (fr) 2014-03-18 2016-04-15 Maco Pharma Sa Procede de synthese d'un derive de psoralene
CN107814784A (zh) * 2017-02-24 2018-03-20 厦门大学 一种咖啡酸内酯及其制备方法、药物组合物与应用
CN112062773B (zh) * 2019-06-11 2021-11-26 中国科学院大连化学物理研究所 一种酸催化4-羟基香豆素与异戊二烯环化反应的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3244729A (en) * 1966-04-05 Dimethoxy-x-methyl-g,y-furanocou- marin compounds
US2889337A (en) * 1956-07-19 1959-06-02 William L Stanley Isolation of furocoumarins
US3201421A (en) * 1962-05-09 1965-08-17 Dept Of Chemistry Preparation of alkyl psoralens
US3553236A (en) * 1968-12-06 1971-01-05 Franco Indian Pharmaceuticals Psoralene and isopsoralene, process for their isolation and separation

Also Published As

Publication number Publication date
DE2741233A1 (de) 1978-03-16
NL7709748A (nl) 1978-03-16
JPS5337694A (en) 1978-04-06
IT1085033B (it) 1985-05-28
US4130568A (en) 1978-12-19
FR2368488A1 (fr) 1978-05-19

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