IT1065683B - Derivati indolici sostituiti con sostituenti basici e processo per la loro preparazione - Google Patents
Derivati indolici sostituiti con sostituenti basici e processo per la loro preparazioneInfo
- Publication number
- IT1065683B IT1065683B IT30582/76A IT3058276A IT1065683B IT 1065683 B IT1065683 B IT 1065683B IT 30582/76 A IT30582/76 A IT 30582/76A IT 3058276 A IT3058276 A IT 3058276A IT 1065683 B IT1065683 B IT 1065683B
- Authority
- IT
- Italy
- Prior art keywords
- substitutes
- basic
- preparation
- derivatives replaced
- indolic derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19752557342 DE2557342A1 (de) | 1975-12-19 | 1975-12-19 | Basisch substituierte indolderivate und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IT1065683B true IT1065683B (it) | 1985-03-04 |
Family
ID=5964905
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT30582/76A IT1065683B (it) | 1975-12-19 | 1976-12-17 | Derivati indolici sostituiti con sostituenti basici e processo per la loro preparazione |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS5277060A (it) |
| AT (1) | ATA936276A (it) |
| BE (1) | BE849626A (it) |
| CA (1) | CA1079739A (it) |
| DE (1) | DE2557342A1 (it) |
| DK (1) | DK571376A (it) |
| FR (1) | FR2335216A1 (it) |
| GB (1) | GB1566307A (it) |
| IT (1) | IT1065683B (it) |
| LU (1) | LU76427A1 (it) |
| NL (1) | NL7614050A (it) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5936675A (ja) * | 1982-07-13 | 1984-02-28 | サンド・アクチエンゲゼルシヤフト | 二環性複素環式カルボン酸アザビシクロアルキルエステルまたはアミド |
| US4476307A (en) * | 1982-09-20 | 1984-10-09 | Pfizer Inc. | Heteroylidene indolone compounds |
| US4977178A (en) * | 1982-09-20 | 1990-12-11 | Pfizer Inc. | Method of treating anxiety and depression with 1-phenyl-2(1H,3H)-indolone psycho-therapeutic agents |
| US4879391A (en) * | 1982-09-20 | 1989-11-07 | Pfizer Inc. | 1-Phenyl-2(1H,3H)-indolone psychotherapeutic agents |
| US4861880A (en) * | 1982-09-20 | 1989-08-29 | Pfizer Inc. | 1-phenyl-2(1H,3H)-indolone psycho-therapeutic agents |
| JPS6084281A (ja) * | 1983-09-14 | 1985-05-13 | Yoshitomi Pharmaceut Ind Ltd | ３−インド−ルカルボキサミド類 |
| FR2557110B1 (fr) * | 1983-12-23 | 1989-11-24 | Sandoz Sa | Nouveaux derives d'amines cycliques, leur preparation et leur utilisation comme medicaments |
| CA2131797C (en) * | 1992-03-12 | 2010-05-18 | Laramie Mary Gaster | Condensed indole derivatives as 5ht4-receptor antagonists |
| US5852014A (en) * | 1992-03-12 | 1998-12-22 | Smithkline Beecham P.L.C. | Condensed indole derivatives as 5HT4 -receptor antagonists |
| ATE206701T1 (de) * | 1996-04-19 | 2001-10-15 | American Home Prod | Östrogene verbindungen |
| US6069153A (en) * | 1998-05-12 | 2000-05-30 | American Home Products Corporation | Indenoindoles and benzocarbazoles as estrogenic agents |
| US6479535B1 (en) | 1998-05-15 | 2002-11-12 | Wyeth | 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indole and estrogen formulations |
| US6159959A (en) * | 1999-05-06 | 2000-12-12 | American Home Products Corporation | Combined estrogen and antiestrogen therapy |
| RS53599B1 (sr) | 2005-05-10 | 2015-02-27 | Intermune, Inc. | Piridon derivati za modulaciju stresom aktiviranog sistema proteinskih kinaza |
| CN102295636A (zh) | 2005-07-29 | 2011-12-28 | 弗·哈夫曼-拉罗切有限公司 | 吲哚-3-基-羰基-哌啶和哌嗪衍生物 |
| JP2009508872A (ja) * | 2005-09-16 | 2009-03-05 | セレネックス， インコーポレイテッド | カルバゾール誘導体 |
| BRPI0812594A2 (pt) * | 2007-08-10 | 2015-06-23 | Lundbeck & Co As H | Composto ou sal ou hidrato do mesmo, composição farmacêutica, métodos para modulação da atividade de um receptor p2x7, para tratamento de uma condição responsiva á modulação do receptor p2x7 em um paciente, para inibição de morte de células gangliônicas retinais em um paciente, para determinação da presença ou ausência de receptor p2x7 em uma amostra, preparação farmacêutica acondicionada, e, uso de um composto ou sal ou hidrato do mesmo. |
| JP5627574B2 (ja) | 2008-06-03 | 2014-11-19 | インターミューン， インコーポレイテッド | 炎症性および線維性疾患を治療するための化合物および方法 |
| AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
| CN106459042B (zh) | 2014-04-02 | 2019-06-28 | 英特穆恩公司 | 抗纤维化吡啶酮类 |
-
1975
- 1975-12-19 DE DE19752557342 patent/DE2557342A1/de not_active Withdrawn
-
1976
- 1976-12-17 NL NL7614050A patent/NL7614050A/xx not_active Application Discontinuation
- 1976-12-17 CA CA268,139A patent/CA1079739A/en not_active Expired
- 1976-12-17 AT AT936276A patent/ATA936276A/de not_active Application Discontinuation
- 1976-12-17 DK DK571376A patent/DK571376A/da not_active Application Discontinuation
- 1976-12-17 LU LU76427A patent/LU76427A1/xx unknown
- 1976-12-17 IT IT30582/76A patent/IT1065683B/it active
- 1976-12-18 JP JP51151501A patent/JPS5277060A/ja active Pending
- 1976-12-20 BE BE173447A patent/BE849626A/xx unknown
- 1976-12-20 GB GB53124/76A patent/GB1566307A/en not_active Expired
- 1976-12-20 FR FR7638400A patent/FR2335216A1/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| BE849626A (fr) | 1977-06-20 |
| DK571376A (da) | 1977-06-20 |
| JPS5277060A (en) | 1977-06-29 |
| GB1566307A (en) | 1980-04-30 |
| ATA936276A (de) | 1980-02-15 |
| NL7614050A (nl) | 1977-06-21 |
| LU76427A1 (it) | 1977-07-05 |
| CA1079739A (en) | 1980-06-17 |
| DE2557342A1 (de) | 1977-06-30 |
| FR2335216A1 (fr) | 1977-07-15 |
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