BE849626A - Nouveaux derives d'indol substitues par des bases, leur procede de preparation et leurs applications - Google Patents

Nouveaux derives d'indol substitues par des bases, leur procede de preparation et leurs applications

Info

Publication number
BE849626A
BE849626A BE173447A BE173447A BE849626A BE 849626 A BE849626 A BE 849626A BE 173447 A BE173447 A BE 173447A BE 173447 A BE173447 A BE 173447A BE 849626 A BE849626 A BE 849626A
Authority
BE
Belgium
Prior art keywords
bases
applications
preparation process
derivatives substituted
indol derivatives
Prior art date
Application number
BE173447A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE849626A publication Critical patent/BE849626A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
BE173447A 1975-12-19 1976-12-20 Nouveaux derives d'indol substitues par des bases, leur procede de preparation et leurs applications BE849626A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752557342 DE2557342A1 (de) 1975-12-19 1975-12-19 Basisch substituierte indolderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
BE849626A true BE849626A (fr) 1977-06-20

Family

ID=5964905

Family Applications (1)

Application Number Title Priority Date Filing Date
BE173447A BE849626A (fr) 1975-12-19 1976-12-20 Nouveaux derives d'indol substitues par des bases, leur procede de preparation et leurs applications

Country Status (11)

Country Link
JP (1) JPS5277060A (fr)
AT (1) ATA936276A (fr)
BE (1) BE849626A (fr)
CA (1) CA1079739A (fr)
DE (1) DE2557342A1 (fr)
DK (1) DK571376A (fr)
FR (1) FR2335216A1 (fr)
GB (1) GB1566307A (fr)
IT (1) IT1065683B (fr)
LU (1) LU76427A1 (fr)
NL (1) NL7614050A (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0104860A1 (fr) * 1982-09-20 1984-04-04 Pfizer Inc. Agents psychothérapeutiques à base de phényl-1(1H,3H)-indolones-2
US4861880A (en) * 1982-09-20 1989-08-29 Pfizer Inc. 1-phenyl-2(1H,3H)-indolone psycho-therapeutic agents
US4879391A (en) * 1982-09-20 1989-11-07 Pfizer Inc. 1-Phenyl-2(1H,3H)-indolone psychotherapeutic agents
US4977178A (en) * 1982-09-20 1990-12-11 Pfizer Inc. Method of treating anxiety and depression with 1-phenyl-2(1H,3H)-indolone psycho-therapeutic agents

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5936675A (ja) * 1982-07-13 1984-02-28 サンド・アクチエンゲゼルシヤフト 二環性複素環式カルボン酸アザビシクロアルキルエステルまたはアミド
JPS6084281A (ja) * 1983-09-14 1985-05-13 Yoshitomi Pharmaceut Ind Ltd ３−インド−ルカルボキサミド類
FR2557110B1 (fr) * 1983-12-23 1989-11-24 Sandoz Sa Nouveaux derives d'amines cycliques, leur preparation et leur utilisation comme medicaments
PT884319E (pt) * 1992-03-12 2004-09-30 Smithkline Beecham Plc N-¬(1-n-butil-4-piperidil)metil|-3,4-di-hidro-2h-¬1,3|oxazino¬3,2-a|indole-10-carboxamida ou um seu sal farmaceuticamente aceitavel
US5852014A (en) * 1992-03-12 1998-12-22 Smithkline Beecham P.L.C. Condensed indole derivatives as 5HT4 -receptor antagonists
EP0802183B1 (fr) * 1996-04-19 2001-10-10 American Home Products Corporation Composés oestrogènes
US6069153A (en) * 1998-05-12 2000-05-30 American Home Products Corporation Indenoindoles and benzocarbazoles as estrogenic agents
US6479535B1 (en) 1998-05-15 2002-11-12 Wyeth 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indole and estrogen formulations
US6159959A (en) * 1999-05-06 2000-12-12 American Home Products Corporation Combined estrogen and antiestrogen therapy
MX2007014114A (es) 2005-05-10 2008-03-14 Intermune Inc Derivados de piridona para modular el sistema de proteina cinasa activada por estres.
EP2392571A3 (fr) * 2005-07-29 2012-03-14 F. Hoffmann-La Roche AG Dérivés d'indol-3-yl-carbonyl-pipéridine et pipérazine
WO2007035620A2 (fr) * 2005-09-16 2007-03-29 Serenex, Inc. Derives de carbazole
EP2185560A4 (fr) * 2007-08-10 2011-10-05 Lundbeck & Co As H Analogues d'hétéroarylamides
CA3034994A1 (fr) 2008-06-03 2009-12-10 Intermune, Inc. Composes et procedes de traitement des troubles inflammatoires et fibrotiques
AR092742A1 (es) 2012-10-02 2015-04-29 Intermune Inc Piridinonas antifibroticas
CN106459042B (zh) 2014-04-02 2019-06-28 英特穆恩公司 抗纤维化吡啶酮类

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0104860A1 (fr) * 1982-09-20 1984-04-04 Pfizer Inc. Agents psychothérapeutiques à base de phényl-1(1H,3H)-indolones-2
US4476307A (en) * 1982-09-20 1984-10-09 Pfizer Inc. Heteroylidene indolone compounds
US4861880A (en) * 1982-09-20 1989-08-29 Pfizer Inc. 1-phenyl-2(1H,3H)-indolone psycho-therapeutic agents
US4879391A (en) * 1982-09-20 1989-11-07 Pfizer Inc. 1-Phenyl-2(1H,3H)-indolone psychotherapeutic agents
US4977178A (en) * 1982-09-20 1990-12-11 Pfizer Inc. Method of treating anxiety and depression with 1-phenyl-2(1H,3H)-indolone psycho-therapeutic agents

Also Published As

Publication number Publication date
GB1566307A (en) 1980-04-30
ATA936276A (de) 1980-02-15
NL7614050A (nl) 1977-06-21
LU76427A1 (fr) 1977-07-05
FR2335216A1 (fr) 1977-07-15
IT1065683B (it) 1985-03-04
DK571376A (da) 1977-06-20
DE2557342A1 (de) 1977-06-30
CA1079739A (fr) 1980-06-17
JPS5277060A (en) 1977-06-29

Similar Documents

Publication Publication Date Title
FR2335215A1 (fr) Derives d'indol substitues par des bases, leur procede de preparation et leurs applications
BE842689A (fr) Nouveaux derives d'isoxazoles, leur procede de preparation et leurs applications
FR2335216A1 (fr) Nouveaux derives d'indol substitues par des bases, leur procede de preparation et leurs applications
FR2315930A1 (fr) Derives de 1,4-dihydropyridine et leur procede de preparation
FR2332009A1 (fr) Nouveaux derives polyprenyliques, leur procede de preparation et leurs applications
FR2312247A1 (fr) Derives de la thieno-pyridine, leur procede de preparation et leurs applications
FR2320295A1 (fr) Nouveaux derives de la 2,3-dioxopiperazine et leur procede de preparation
BE845317A (fr) Nouveaux procede de preparation d'azines
BE861503R (fr) Nouveaux derives d'isoxazoles, leur procede de preparation et leurs applications
FR2321297A1 (fr) Nouveaux derives de dopamine, leur procede de preparation et leurs applications
FR2313930A1 (fr) Derives d'eburnamenine, leur procede de preparation et leurs applications
BE842059A (fr) Nouveaux benzamides substitues, leurs derives et leur procede de preparation
BE844229A (fr) Nouveaux derives d'apovincaminol leur procede de preparation et leur application
BE819321A (fr) Nouveaux 2,3-dihydrobenzofuranyl-7-n-methyl-carbamates n-sulfenyles, leur procede de preparation et leur application
FR2290207A1 (fr) Nouveaux derives de 3,4-dihydrocarbostyril et leur procede de preparation
CH554353A (fr) Procede de preparation de nouveaux derives de l'isoindoline.
FR2321894A1 (fr) Nouveaux derives de phenothiazine, leur procede de preparation et leurs applications
BE847352A (fr) Nouveaux derives de thiazolidine, leur procede de preparation et leurs applications
FR2337550A1 (fr) Nouveaux derives de l'hydrazine, leur procede de preparation et leurs applications
BE831855A (fr) Nouveaux derives d'oxyphenylbutazone et leur procede de preparation
BE845700A (fr) Derives du vincane substitues en position 14, et leur procede de preparation
BE848627A (fr) Derives substitues d'aminobenzaldehydes et leur procede de preparation,
BE843576A (fr) Derives de 1,4-dihydropyridine et leur procede de preparation
FR2309233A1 (fr) Derives de 7-methoxycephalosporine, leur procede de preparation et leurs applications
BE842276A (fr) Nouveaux derives de prostane et leur procede de preparation