IT1045797B - Procedimento per la sintesi enzimatica di penicilline e cefalosporine semisintetiche mediante una acilasi insolubile - Google Patents
Procedimento per la sintesi enzimatica di penicilline e cefalosporine semisintetiche mediante una acilasi insolubileInfo
- Publication number
- IT1045797B IT1045797B IT54486/73A IT5448673A IT1045797B IT 1045797 B IT1045797 B IT 1045797B IT 54486/73 A IT54486/73 A IT 54486/73A IT 5448673 A IT5448673 A IT 5448673A IT 1045797 B IT1045797 B IT 1045797B
- Authority
- IT
- Italy
- Prior art keywords
- cephalosporine
- acylase
- insoluble
- semi
- synthesis procedure
- Prior art date
Links
- HOKIDJSKDBPKTQ-UHFFFAOYSA-N 3-(acetyloxymethyl)-7-[(5-amino-5-carboxypentanoyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)C(NC(=O)CCCC(N)C(O)=O)C12 HOKIDJSKDBPKTQ-UHFFFAOYSA-N 0.000 title 1
- 229930182555 Penicillin Natural products 0.000 title 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 229940049954 penicillin Drugs 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
- C12P35/04—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by acylation of the substituent in the 7 position
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Cephalosporin Compounds (AREA)
Priority Applications (20)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT54486/73A IT1045797B (it) | 1973-12-20 | 1973-12-20 | Procedimento per la sintesi enzimatica di penicilline e cefalosporine semisintetiche mediante una acilasi insolubile |
| IL46151A IL46151A0 (en) | 1973-12-20 | 1974-11-28 | Process for the enzymatic synthesis of semi synthetic penicillins and cephalosporins by means of an insoluble acylase |
| AU75938/74A AU7593874A (en) | 1973-12-20 | 1974-12-02 | Enzymatic synthesis of semisynthetic penicillins and cephalosporins |
| FR7439837A FR2255379B1 (enrdf_load_stackoverflow) | 1973-12-20 | 1974-12-05 | |
| CH1640174A CH606432A5 (enrdf_load_stackoverflow) | 1973-12-20 | 1974-12-10 | |
| ZA00747896A ZA747896B (en) | 1973-12-20 | 1974-12-11 | Process for the enzymatic synthesis of semisynthetic penicillins and cephalosporins by means of an insoluble acylase |
| LU71482A LU71482A1 (enrdf_load_stackoverflow) | 1973-12-20 | 1974-12-13 | |
| FI3621/74A FI362174A7 (enrdf_load_stackoverflow) | 1973-12-20 | 1974-12-16 | |
| GB54337/74A GB1482481A (en) | 1973-12-20 | 1974-12-16 | Enzymatic synthesis |
| BE151539A BE823393A (fr) | 1973-12-20 | 1974-12-16 | Procede de synthese enzymatique de penicillines et de cephalosporines semi-synthetiques au moyen d'une acylase insoluble |
| YU03355/74A YU335574A (en) | 1973-12-20 | 1974-12-17 | Process for the enzymatic synthesis of semisynthetic penicillins and cephalosporins by means of insoluble ecylase |
| NL7416548A NL7416548A (nl) | 1973-12-20 | 1974-12-18 | Werkwijze voor de enzymatische bereiding van half-synthetische penicillinen en cefalospori- nen met behulp van een onoplosbaar acylase. |
| DK661074A DK661074A (enrdf_load_stackoverflow) | 1973-12-20 | 1974-12-18 | |
| HU74SA00002732A HU172712B (hu) | 1973-12-20 | 1974-12-19 | Sposob poluchenija semisintetichnykh cefalosporinov enzimom, to est' nerostvorimym penicillin-acilazom |
| NO744591A NO744591L (enrdf_load_stackoverflow) | 1973-12-20 | 1974-12-19 | |
| SE7416078A SE7416078L (enrdf_load_stackoverflow) | 1973-12-20 | 1974-12-19 | |
| DE19742460649 DE2460649A1 (de) | 1973-12-20 | 1974-12-20 | Verfahren zur enzymatischen synthese von halbsynthetischen penicillinen und cephalosporinen durch eine unloesliche acylase |
| DD183278A DD115683A5 (enrdf_load_stackoverflow) | 1973-12-20 | 1974-12-20 | |
| CS748820A CS190459B2 (en) | 1973-12-20 | 1974-12-20 | Method of enzymatic synthesis of semi-synthetic penicillins and cephalosporins by insoluble acylase |
| JP49145851A JPS5095487A (enrdf_load_stackoverflow) | 1973-12-20 | 1974-12-20 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT54486/73A IT1045797B (it) | 1973-12-20 | 1973-12-20 | Procedimento per la sintesi enzimatica di penicilline e cefalosporine semisintetiche mediante una acilasi insolubile |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IT1045797B true IT1045797B (it) | 1980-06-10 |
Family
ID=11287339
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT54486/73A IT1045797B (it) | 1973-12-20 | 1973-12-20 | Procedimento per la sintesi enzimatica di penicilline e cefalosporine semisintetiche mediante una acilasi insolubile |
Country Status (20)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1243800B (it) * | 1990-08-28 | 1994-06-28 | Sclavo Spa | Procedimento migliorato per la preparazione di cefalosporine |
| CZ69593A3 (en) * | 1992-04-24 | 1993-12-15 | Lilly Co Eli | Process for preparing cephalosporins |
| IT1274658B (it) * | 1995-02-28 | 1997-07-18 | Acs Dobfar Spa | Procedimento enzimatico migliorato per la produzione di penicilline e cefalosporine |
-
1973
- 1973-12-20 IT IT54486/73A patent/IT1045797B/it active
-
1974
- 1974-11-28 IL IL46151A patent/IL46151A0/xx unknown
- 1974-12-02 AU AU75938/74A patent/AU7593874A/en not_active Expired
- 1974-12-05 FR FR7439837A patent/FR2255379B1/fr not_active Expired
- 1974-12-10 CH CH1640174A patent/CH606432A5/xx not_active IP Right Cessation
- 1974-12-11 ZA ZA00747896A patent/ZA747896B/xx unknown
- 1974-12-13 LU LU71482A patent/LU71482A1/xx unknown
- 1974-12-16 GB GB54337/74A patent/GB1482481A/en not_active Expired
- 1974-12-16 FI FI3621/74A patent/FI362174A7/fi unknown
- 1974-12-16 BE BE151539A patent/BE823393A/xx not_active IP Right Cessation
- 1974-12-17 YU YU03355/74A patent/YU335574A/xx unknown
- 1974-12-18 DK DK661074A patent/DK661074A/da unknown
- 1974-12-18 NL NL7416548A patent/NL7416548A/xx unknown
- 1974-12-19 HU HU74SA00002732A patent/HU172712B/hu unknown
- 1974-12-19 NO NO744591A patent/NO744591L/no unknown
- 1974-12-19 SE SE7416078A patent/SE7416078L/xx unknown
- 1974-12-20 JP JP49145851A patent/JPS5095487A/ja active Pending
- 1974-12-20 DD DD183278A patent/DD115683A5/xx unknown
- 1974-12-20 CS CS748820A patent/CS190459B2/cs unknown
- 1974-12-20 DE DE19742460649 patent/DE2460649A1/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ZA747896B (en) | 1975-12-31 |
| CH606432A5 (enrdf_load_stackoverflow) | 1978-10-31 |
| NL7416548A (nl) | 1975-06-24 |
| NO744591L (enrdf_load_stackoverflow) | 1975-07-14 |
| YU335574A (en) | 1982-05-31 |
| IL46151A0 (en) | 1975-02-10 |
| AU7593874A (en) | 1976-06-03 |
| HU172712B (hu) | 1978-11-28 |
| DK661074A (enrdf_load_stackoverflow) | 1975-08-25 |
| SE7416078L (enrdf_load_stackoverflow) | 1975-06-23 |
| GB1482481A (en) | 1977-08-10 |
| FR2255379B1 (enrdf_load_stackoverflow) | 1977-10-28 |
| LU71482A1 (enrdf_load_stackoverflow) | 1975-06-17 |
| FR2255379A1 (enrdf_load_stackoverflow) | 1975-07-18 |
| DE2460649A1 (de) | 1975-06-26 |
| FI362174A7 (enrdf_load_stackoverflow) | 1975-06-21 |
| JPS5095487A (enrdf_load_stackoverflow) | 1975-07-29 |
| DD115683A5 (enrdf_load_stackoverflow) | 1975-10-12 |
| BE823393A (fr) | 1975-04-16 |
| CS190459B2 (en) | 1979-05-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SE385767B (sv) | Forband for laryngektomerade patienter | |
| JPS5745188A (en) | Manufacture of penicillin compound | |
| JPS57112397A (en) | Manufacture of novel cephalosporin | |
| AU466461B2 (en) | Pharmaceutical preparations of penicillin compounds for rectal use | |
| IT1006207B (it) | Iniziatori di fotopolimerizzazione | |
| IL43926A0 (en) | Bulk-polymerization of acylonitrile | |
| IT1045797B (it) | Procedimento per la sintesi enzimatica di penicilline e cefalosporine semisintetiche mediante una acilasi insolubile | |
| IT1006420B (it) | Procedimento di polimerizzazione di clorociclofosfazeni | |
| AU466331B2 (en) | Preparation of n-(1-ethyl-pyrrolidylmethyl)-2-methoxy-5-sulfonamidobenzamide | |
| JPS5775985A (en) | Manufacture of substituted penicillins | |
| SE7703567L (sv) | Forfarande for framstellning av aminoacyldipeptidpenicilliner | |
| AU471164B2 (en) | Preparation of n-(1-ethyl-2-pyrrolidymethyl) 2-methoxy-5-ethysulphonyl-benzamide | |
| NO142784C (no) | Forbindelse for fremstilling av n-substituerte prostaglandin-karboksamider | |
| BE792886A (fr) | Derives carboxamido-acyles de la penicilline | |
| IL41027A0 (en) | The preparation of semi-synthetic penicillins and cephalosporins and novel intermediates used therein | |
| IT1019743B (it) | Mezzi di accoppiamento | |
| CA882746A (en) | Preparation of p-halosubstituted bisphenyl acetals of n-amidinoglyoxyl amide | |
| IT1026523B (it) | Preparazione di triaril rosfine | |
| AU464143B2 (en) | Preparation of n-(1-ethyl-7-pyrrolidylmethyl)-2-methoxy-5-sulfonamidobenzamide | |
| IT1005663B (it) | Addotti di polipentenameri | |
| BE822141A (fr) | Nouveaux derives de la cephalosporine | |
| AU478969B2 (en) | Synthesis of some cephalosporin derivatives | |
| IT1033030B (it) | Procedimento per la preparazione di penicilline semisintetiche | |
| CA837578A (en) | Purification of penicillin amidase | |
| FI54132C (fi) | Foerfarande foer framstaellning av terapeutiskt anvaendbara 15alfa 16alfa-metylen-4-estren-17beta-oler |