CS190459B2 - Method of enzymatic synthesis of semi-synthetic penicillins and cephalosporins by insoluble acylase - Google Patents

Method of enzymatic synthesis of semi-synthetic penicillins and cephalosporins by insoluble acylase

Info

Publication number
CS190459B2
CS190459B2 CS748820A CS882074A CS190459B2 CS 190459 B2 CS190459 B2 CS 190459B2 CS 748820 A CS748820 A CS 748820A CS 882074 A CS882074 A CS 882074A CS 190459 B2 CS190459 B2 CS 190459B2
Authority
CS
Czechoslovakia
Prior art keywords
acylase
cephalosporins
insoluble
semi
enzymatic synthesis
Prior art date
Application number
CS748820A
Other languages
Czech (cs)
English (en)
Inventor
Francesco Bartoli
Francesco Cecere
Giuliano Galli
Original Assignee
Snam Progetti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Snam Progetti filed Critical Snam Progetti
Publication of CS190459B2 publication Critical patent/CS190459B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/04—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by acylation of the substituent in the 7 position
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
CS748820A 1973-12-20 1974-12-20 Method of enzymatic synthesis of semi-synthetic penicillins and cephalosporins by insoluble acylase CS190459B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT54486/73A IT1045797B (it) 1973-12-20 1973-12-20 Procedimento per la sintesi enzimatica di penicilline e cefalosporine semisintetiche mediante una acilasi insolubile

Publications (1)

Publication Number Publication Date
CS190459B2 true CS190459B2 (en) 1979-05-31

Family

ID=11287339

Family Applications (1)

Application Number Title Priority Date Filing Date
CS748820A CS190459B2 (en) 1973-12-20 1974-12-20 Method of enzymatic synthesis of semi-synthetic penicillins and cephalosporins by insoluble acylase

Country Status (20)

Country Link
JP (1) JPS5095487A (enrdf_load_stackoverflow)
AU (1) AU7593874A (enrdf_load_stackoverflow)
BE (1) BE823393A (enrdf_load_stackoverflow)
CH (1) CH606432A5 (enrdf_load_stackoverflow)
CS (1) CS190459B2 (enrdf_load_stackoverflow)
DD (1) DD115683A5 (enrdf_load_stackoverflow)
DE (1) DE2460649A1 (enrdf_load_stackoverflow)
DK (1) DK661074A (enrdf_load_stackoverflow)
FI (1) FI362174A7 (enrdf_load_stackoverflow)
FR (1) FR2255379B1 (enrdf_load_stackoverflow)
GB (1) GB1482481A (enrdf_load_stackoverflow)
HU (1) HU172712B (enrdf_load_stackoverflow)
IL (1) IL46151A0 (enrdf_load_stackoverflow)
IT (1) IT1045797B (enrdf_load_stackoverflow)
LU (1) LU71482A1 (enrdf_load_stackoverflow)
NL (1) NL7416548A (enrdf_load_stackoverflow)
NO (1) NO744591L (enrdf_load_stackoverflow)
SE (1) SE7416078L (enrdf_load_stackoverflow)
YU (1) YU335574A (enrdf_load_stackoverflow)
ZA (1) ZA747896B (enrdf_load_stackoverflow)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1243800B (it) * 1990-08-28 1994-06-28 Sclavo Spa Procedimento migliorato per la preparazione di cefalosporine
NZ247464A (en) * 1992-04-24 1994-12-22 Lilly Co Eli Preparation of 2-amino-acetamidocephalosporin derivatives, the 2-acetamido group substituted in the 2-position by a c5-6 cyclic hydrocarbon or a c5-heterocycle
IT1274658B (it) * 1995-02-28 1997-07-18 Acs Dobfar Spa Procedimento enzimatico migliorato per la produzione di penicilline e cefalosporine

Also Published As

Publication number Publication date
AU7593874A (en) 1976-06-03
LU71482A1 (enrdf_load_stackoverflow) 1975-06-17
IT1045797B (it) 1980-06-10
IL46151A0 (en) 1975-02-10
CH606432A5 (enrdf_load_stackoverflow) 1978-10-31
DD115683A5 (enrdf_load_stackoverflow) 1975-10-12
FI362174A7 (enrdf_load_stackoverflow) 1975-06-21
HU172712B (hu) 1978-11-28
DE2460649A1 (de) 1975-06-26
YU335574A (en) 1982-05-31
NO744591L (enrdf_load_stackoverflow) 1975-07-14
JPS5095487A (enrdf_load_stackoverflow) 1975-07-29
FR2255379B1 (enrdf_load_stackoverflow) 1977-10-28
DK661074A (enrdf_load_stackoverflow) 1975-08-25
NL7416548A (nl) 1975-06-24
FR2255379A1 (enrdf_load_stackoverflow) 1975-07-18
BE823393A (fr) 1975-04-16
GB1482481A (en) 1977-08-10
ZA747896B (en) 1975-12-31
SE7416078L (enrdf_load_stackoverflow) 1975-06-23

Similar Documents

Publication Publication Date Title
CA1023344A (en) Process for preparing penicillins and cephalosporins
JPS5323988A (en) Production of penicillin and cephalosporin
ZA725754B (en) Enzymatic production of cephalexin
CA1026321A (en) Tetrabutylammonium salts of penicillins and cephalosporins
CS190459B2 (en) Method of enzymatic synthesis of semi-synthetic penicillins and cephalosporins by insoluble acylase
GB1544844A (en) Enzymatic acylation to produce penicillins and cephalosporins
YU216679A (en) Process for the enzymatic synthesis of semisynthetic penicillins
GB1404846A (en) Intermediates for producing semi-synthetic penicillins and cephalosporins and methods of production
PT65518B (en) Process for the preparation of novel penicillins and cephalosporins
CA1024981A (en) Intermediates for preparing semi-synthetic penicillins and cephalosporins and processes relating thereto
YU335674A (en) Process for the enzymatic hydrolysis of cephalosporins derived by chemical enlargening of the penicillin g ring and the enzymatic synthesis of semisynthetic cephalosporins
CA1021320A (en) Amino esters of penicillins and cephalosporins
ZA717343B (en) Procedure for enzymatic production of semi-synthetic penicillins
JPS57197281A (en) Cleavage of cephalosporins
IE39550B1 (en) Enzymic hydrolysis of 3-acyloxymethyl cephalosporins
IE36816B1 (en) Intermediates for producing semi-synthetic penicillins and cephalosporins and methods of production
IL47380A0 (en) Process and intermediates for the preparation of penicillins and cephalosporins
AU477013B2 (en) Enzymatic aclation or deacylation of penicillins and cephalosporins
AU483588B2 (en) New derivatives of penicillins and cephalosporins
AU486539B2 (en) Tetraalkyl ammonium salts of penicillins and cephalosporins
AU7476374A (en) New derivatives of penicillins and cephalosporins
AU426561B2 (en) Process forthe preparation of penicillins and cephalosporins
CA1022924A (en) Preparation of syn alpha-hydroxylminoacylamido and alpha-acyloxylminoacylamido penicillins and cephalosporins
CS182374B1 (en) Cultivating medium for the submerged fermentation of penicillins
AU6373969A (en) Process forthe preparation of penicillins and cephalosporins