IT1044268B - Procedimento per la preparazione del composto 17 alfa etinil 5 alfa 2 androstene 17 beta ol e del relativo acetato 17 beta allo stato puro la sua miscela al suo isomero delta 3 e le applicazioni terapeutiche del composto ottenuto col procedimento - Google Patents
Procedimento per la preparazione del composto 17 alfa etinil 5 alfa 2 androstene 17 beta ol e del relativo acetato 17 beta allo stato puro la sua miscela al suo isomero delta 3 e le applicazioni terapeutiche del composto ottenuto col procedimentoInfo
- Publication number
- IT1044268B IT1044268B IT19319/75A IT1931975A IT1044268B IT 1044268 B IT1044268 B IT 1044268B IT 19319/75 A IT19319/75 A IT 19319/75A IT 1931975 A IT1931975 A IT 1931975A IT 1044268 B IT1044268 B IT 1044268B
- Authority
- IT
- Italy
- Prior art keywords
- alfa
- beta
- procedure
- compound
- etinil
- Prior art date
Links
- AOSZTAHDEDLTLQ-AZKQZHLXSA-N (1S,2S,4R,8S,9S,11S,12R,13S,19S)-6-[(3-chlorophenyl)methyl]-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-azapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one Chemical compound C([C@@H]1C[C@H]2[C@H]3[C@]([C@]4(C=CC(=O)C=C4[C@@H](F)C3)C)(F)[C@@H](O)C[C@@]2([C@@]1(C1)C(=O)CO)C)N1CC1=CC=CC(Cl)=C1 AOSZTAHDEDLTLQ-AZKQZHLXSA-N 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 title 1
- 229940126657 Compound 17 Drugs 0.000 title 1
- NXQOQNROJJFYCJ-FZFXZXLVSA-N androst-16-ene Chemical compound C1CCC[C@]2(C)[C@H]3CC[C@](C)(C=CC4)[C@@H]4[C@@H]3CCC21 NXQOQNROJJFYCJ-FZFXZXLVSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J11/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2211/74A GB1492746A (en) | 1974-01-17 | 1974-01-17 | Androstane derivatives and compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IT1044268B true IT1044268B (it) | 1980-03-20 |
Family
ID=9735557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT19319/75A IT1044268B (it) | 1974-01-17 | 1975-01-16 | Procedimento per la preparazione del composto 17 alfa etinil 5 alfa 2 androstene 17 beta ol e del relativo acetato 17 beta allo stato puro la sua miscela al suo isomero delta 3 e le applicazioni terapeutiche del composto ottenuto col procedimento |
Country Status (19)
| Country | Link |
|---|---|
| JP (1) | JPS576439B2 (enExample) |
| AR (1) | AR203672A1 (enExample) |
| AU (1) | AU521392B2 (enExample) |
| BE (1) | BE823594A (enExample) |
| BR (1) | BR7500346A (enExample) |
| CA (1) | CA1065851A (enExample) |
| CH (1) | CH606091A5 (enExample) |
| DE (1) | DE2501091A1 (enExample) |
| DK (1) | DK135538B (enExample) |
| ES (1) | ES433677A1 (enExample) |
| FR (1) | FR2258185B1 (enExample) |
| GB (1) | GB1492746A (enExample) |
| IE (1) | IE40477B1 (enExample) |
| IT (1) | IT1044268B (enExample) |
| LU (1) | LU71662A1 (enExample) |
| NL (1) | NL183402C (enExample) |
| PH (1) | PH15366A (enExample) |
| SE (1) | SE7500479L (enExample) |
| ZA (1) | ZA75254B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0066001B1 (en) * | 1981-06-02 | 1986-05-14 | Laboratoire Théramex | Pharmaceutical compositions containing androstenes |
| JPS60173248A (ja) * | 1984-02-16 | 1985-09-06 | 三晃金属工業株式会社 | 嵌合外囲体 |
| US5116830A (en) * | 1984-08-17 | 1992-05-26 | Sri International | Stereoisomerically pure 17α-ethynyl-estra-2-en-17β-ol and the 17β esters thereof, methods of preparation and uses |
| JPS61503032A (ja) * | 1984-08-17 | 1986-12-25 | エス・ア−ル・アイ・インタ−ナシヨナル | 立体異性的に純粋な１７α−エチニル−エストラ−２−エン−１７β−オ−ルおよびその１７β−エステル、製造方法および用途 |
| DE3661832D1 (en) * | 1985-04-29 | 1989-02-23 | Theramex | Process for the preparation of pure androst-2-ene derivatives |
| FR2598083B1 (fr) * | 1986-05-05 | 1989-12-29 | Theramex Laboratoire | Nouvelles compositions pharmaceutiques a action antiprogesteronique et leur procede d'obtention |
| RU2652702C2 (ru) | 2016-10-19 | 2018-04-28 | Игорь Ву-Юнович Ван | Субатмосферная система теплохолодоснабжения |
-
1974
- 1974-01-17 GB GB2211/74A patent/GB1492746A/en not_active Expired
- 1974-12-18 CH CH1734774A patent/CH606091A5/xx not_active IP Right Cessation
- 1974-12-19 BE BE151716A patent/BE823594A/xx unknown
- 1974-12-30 DK DK690574AA patent/DK135538B/da not_active IP Right Cessation
- 1974-12-31 FR FR7443397A patent/FR2258185B1/fr not_active Expired
-
1975
- 1975-01-09 ES ES433677A patent/ES433677A1/es not_active Expired
- 1975-01-13 DE DE19752501091 patent/DE2501091A1/de active Pending
- 1975-01-14 ZA ZA00750254A patent/ZA75254B/xx unknown
- 1975-01-14 JP JP698075A patent/JPS576439B2/ja not_active Expired
- 1975-01-15 AU AU77335/75A patent/AU521392B2/en not_active Expired
- 1975-01-16 LU LU71662A patent/LU71662A1/xx unknown
- 1975-01-16 IT IT19319/75A patent/IT1044268B/it active
- 1975-01-16 PH PH16719A patent/PH15366A/en unknown
- 1975-01-16 SE SE7500479A patent/SE7500479L/xx unknown
- 1975-01-16 CA CA218,033A patent/CA1065851A/fr not_active Expired
- 1975-01-17 AR AR257331A patent/AR203672A1/es active
- 1975-01-17 IE IE83/75A patent/IE40477B1/xx unknown
- 1975-01-17 NL NLAANVRAGE7500608,A patent/NL183402C/xx not_active IP Right Cessation
- 1975-01-17 BR BR346/75A patent/BR7500346A/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU7733575A (en) | 1976-07-15 |
| DE2501091A1 (de) | 1975-07-24 |
| NL183402B (nl) | 1988-05-16 |
| LU71662A1 (enExample) | 1975-06-24 |
| FR2258185B1 (enExample) | 1978-07-28 |
| AU521392B2 (en) | 1982-04-01 |
| NL183402C (nl) | 1988-10-17 |
| JPS50106952A (enExample) | 1975-08-22 |
| DK135538C (enExample) | 1977-10-24 |
| PH15366A (en) | 1982-12-10 |
| GB1492746A (en) | 1977-11-23 |
| DK135538B (da) | 1977-05-16 |
| IE40477B1 (en) | 1979-06-06 |
| CA1065851A (fr) | 1979-11-06 |
| AR203672A1 (es) | 1975-09-30 |
| SE7500479L (enExample) | 1975-07-18 |
| BE823594A (fr) | 1975-04-16 |
| ZA75254B (en) | 1976-01-28 |
| CH606091A5 (enExample) | 1978-10-13 |
| FR2258185A1 (enExample) | 1975-08-18 |
| JPS576439B2 (enExample) | 1982-02-04 |
| DK690574A (enExample) | 1975-09-29 |
| ES433677A1 (es) | 1976-11-16 |
| IE40477L (en) | 1975-07-17 |
| BR7500346A (pt) | 1975-11-04 |
| NL7500608A (nl) | 1975-07-21 |
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