IT1038094B - Composti eterociclici derivati dal benzo b tiofene e composizioni farmaceutiche dello stesso nonche procedimento per la preparazione dei derivati del benzo b tiofene - Google Patents
Composti eterociclici derivati dal benzo b tiofene e composizioni farmaceutiche dello stesso nonche procedimento per la preparazione dei derivati del benzo b tiofeneInfo
- Publication number
- IT1038094B IT1038094B IT23297/75A IT2329775A IT1038094B IT 1038094 B IT1038094 B IT 1038094B IT 23297/75 A IT23297/75 A IT 23297/75A IT 2329775 A IT2329775 A IT 2329775A IT 1038094 B IT1038094 B IT 1038094B
- Authority
- IT
- Italy
- Prior art keywords
- benzo
- thiofene
- thiophene
- derivatives
- procedure
- Prior art date
Links
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 title 2
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229930192474 thiophene Natural products 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2525674A GB1456323A (en) | 1974-06-06 | 1974-06-06 | Benzothiophenes process for preparing them and pharmaceutical compositions containing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IT1038094B true IT1038094B (it) | 1979-11-20 |
Family
ID=10224753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT23297/75A IT1038094B (it) | 1974-06-06 | 1975-05-14 | Composti eterociclici derivati dal benzo b tiofene e composizioni farmaceutiche dello stesso nonche procedimento per la preparazione dei derivati del benzo b tiofene |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4007204A (cg-RX-API-DMAC10.html) |
| JP (1) | JPS516958A (cg-RX-API-DMAC10.html) |
| AR (2) | AR207152A1 (cg-RX-API-DMAC10.html) |
| AT (1) | AT341517B (cg-RX-API-DMAC10.html) |
| BE (1) | BE829837A (cg-RX-API-DMAC10.html) |
| CA (1) | CA1030972A (cg-RX-API-DMAC10.html) |
| CH (1) | CH605910A5 (cg-RX-API-DMAC10.html) |
| DE (1) | DE2522655A1 (cg-RX-API-DMAC10.html) |
| DK (1) | DK135808B (cg-RX-API-DMAC10.html) |
| ES (1) | ES438303A1 (cg-RX-API-DMAC10.html) |
| FI (1) | FI751602A7 (cg-RX-API-DMAC10.html) |
| GB (1) | GB1456323A (cg-RX-API-DMAC10.html) |
| HU (1) | HU172820B (cg-RX-API-DMAC10.html) |
| IT (1) | IT1038094B (cg-RX-API-DMAC10.html) |
| NL (1) | NL7504921A (cg-RX-API-DMAC10.html) |
| NO (1) | NO751989L (cg-RX-API-DMAC10.html) |
| OA (1) | OA05022A (cg-RX-API-DMAC10.html) |
| SE (1) | SE7505482L (cg-RX-API-DMAC10.html) |
| SU (1) | SU578002A3 (cg-RX-API-DMAC10.html) |
| ZA (1) | ZA752871B (cg-RX-API-DMAC10.html) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4133814A (en) * | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
| AU509682B2 (en) * | 1975-10-28 | 1980-05-22 | Eli Lilly And Company | 2-Aroyl-3-Phenylbenzothiophene Derivatives |
| US5175184A (en) * | 1982-10-19 | 1992-12-29 | Kotobuki Seiyaku Company Limited | Benzothiophene derivatives and antihyperuricemia thereof |
| NZ213986A (en) * | 1984-10-30 | 1989-07-27 | Usv Pharma Corp | Heterocyclic or aromatic compounds, and pharmaceutical compositions containing such |
| US4806663A (en) * | 1987-04-06 | 1989-02-21 | The University Of Tennessee Research Corporation | Certain 3-substituted 2-alkyl benzofuran derivatives |
| US4851554A (en) * | 1987-04-06 | 1989-07-25 | University Of Tennessee Research Corporation | Certain 3-substituted 2-alkyl benzofuran derivatives |
| US4912642A (en) * | 1987-09-03 | 1990-03-27 | The Boeing Company | Coordinated engine autothrottle |
| AU2543388A (en) * | 1987-09-30 | 1989-04-18 | University Of Tennessee Research Corporation, The | Certain 3-substituted 2-alkyl benzothiophene derivatives |
| US4831156A (en) * | 1987-09-30 | 1989-05-16 | The University Of Tennessee Research Corp. | 3-substituted 2-alkyl indole derivatives |
| JP3157882B2 (ja) * | 1991-11-15 | 2001-04-16 | 帝国臓器製薬株式会社 | 新規なベンゾチオフエン誘導体 |
| US5789436A (en) * | 1994-04-11 | 1998-08-04 | Chugai Seiyak Kabushiki Kaisha | 4,6 Di-t-butyl-5-hydroxy-2,3-dihydrobenzothiophene |
| CO4410190A1 (es) * | 1994-09-19 | 1997-01-09 | Lilly Co Eli | 3-[4-(2-AMINOETOXI)-BENZOIL]-2-ARIL-6-HIDROXIBENZO [b] TIOFENO CRISTALINO |
| US6653328B1 (en) * | 1995-03-10 | 2003-11-25 | Eli Lilly And Company | 3-benzyl-benzothiophenes |
| US6417199B1 (en) * | 1995-03-10 | 2002-07-09 | Eli Lilly And Company | 3-benzyl-benzothiophenes |
| CA2236007A1 (en) * | 1995-10-31 | 1997-07-17 | Gerald Floyd Smith | Antithrombotic diamines |
| JP2000506885A (ja) * | 1996-03-19 | 2000-06-06 | イーライ・リリー・アンド・カンパニー | 3―[4―(2―アミノエトキシ)ベンゾイル]―2―アリール―6―ヒドロキシベンゾ[b]チオフェンの合成 |
| CA2287993A1 (en) | 1997-04-30 | 1998-11-05 | Mary George Johnson | Antithrombotic agents |
| AU7165398A (en) * | 1997-04-30 | 1998-11-24 | Eli Lilly And Company | A regioselective alkylation process for preparing substituted benzo{b}thiophenes |
| JP2002514217A (ja) | 1997-04-30 | 2002-05-14 | イーライ・リリー・アンド・カンパニー | 抗血栓物質 |
| EP1027051B1 (en) | 1997-04-30 | 2005-01-05 | Eli Lilly And Company | Antithrombotic agents |
| DE69824410T2 (de) | 1997-04-30 | 2005-06-02 | Eli Lilly And Co., Indianapolis | Antithrombosemittel |
| US6284756B1 (en) | 1998-04-30 | 2001-09-04 | Eli Lilly And Company | Antithrombotic agents |
| DE69904427T2 (de) * | 1998-10-28 | 2003-07-17 | Eli Lilly And Co., Indianapolis | Benzothiophenderivate als antithrombotische Mitteln und Zwischenprodukte |
| FR2864536B1 (fr) * | 2003-12-24 | 2006-03-17 | Clariant France Sa | Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre |
| NZ606595A (en) * | 2010-08-06 | 2014-08-29 | Tasly Pharmaceutical Group Co | Use of salvia miltiorrhiza composition in preparing drugs for secondary prevention of coronary heart disease |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3514465A (en) * | 1966-12-30 | 1970-05-26 | Degussa | Certain thiazolyl- and pyridinylaminoketones |
| US3706747A (en) * | 1970-06-05 | 1972-12-19 | Pfizer | Benzothieno(3,2-d)- and benzofuro(3,2-d)pyrimidines |
-
1974
- 1974-06-06 GB GB2525674A patent/GB1456323A/en not_active Expired
-
1975
- 1975-01-01 AR AR258913A patent/AR207152A1/es active
- 1975-04-21 US US05/569,819 patent/US4007204A/en not_active Expired - Lifetime
- 1975-04-25 NL NL7504921A patent/NL7504921A/xx not_active Application Discontinuation
- 1975-05-02 ZA ZA00752871A patent/ZA752871B/xx unknown
- 1975-05-13 SE SE7505482A patent/SE7505482L/xx unknown
- 1975-05-14 IT IT23297/75A patent/IT1038094B/it active
- 1975-05-22 DE DE19752522655 patent/DE2522655A1/de active Pending
- 1975-05-30 FI FI751602A patent/FI751602A7/fi not_active Application Discontinuation
- 1975-05-30 HU HU75LA00000867A patent/HU172820B/hu unknown
- 1975-06-04 DK DK251975AA patent/DK135808B/da unknown
- 1975-06-04 BE BE157003A patent/BE829837A/xx unknown
- 1975-06-05 SU SU7502143254A patent/SU578002A3/ru active
- 1975-06-05 NO NO751989A patent/NO751989L/no unknown
- 1975-06-06 ES ES438303A patent/ES438303A1/es not_active Expired
- 1975-06-06 JP JP50069021A patent/JPS516958A/ja active Pending
- 1975-06-06 CH CH730375A patent/CH605910A5/xx not_active IP Right Cessation
- 1975-06-06 AT AT431175A patent/AT341517B/de not_active IP Right Cessation
- 1975-06-06 OA OA55520A patent/OA05022A/xx unknown
- 1975-06-06 CA CA228,687A patent/CA1030972A/en not_active Expired
- 1975-11-07 AR AR261103A patent/AR210265A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| CH605910A5 (cg-RX-API-DMAC10.html) | 1978-10-13 |
| OA05022A (fr) | 1980-12-31 |
| ZA752871B (en) | 1976-04-28 |
| GB1456323A (en) | 1976-11-24 |
| AT341517B (de) | 1978-02-10 |
| DE2522655A1 (de) | 1975-12-18 |
| FI751602A7 (cg-RX-API-DMAC10.html) | 1975-12-07 |
| DK251975A (cg-RX-API-DMAC10.html) | 1975-12-07 |
| AU8102275A (en) | 1976-11-11 |
| ES438303A1 (es) | 1977-01-16 |
| HU172820B (hu) | 1978-12-28 |
| SU578002A3 (ru) | 1977-10-25 |
| CA1030972A (en) | 1978-05-09 |
| BE829837A (fr) | 1975-12-04 |
| US4007204A (en) | 1977-02-08 |
| DK135808C (cg-RX-API-DMAC10.html) | 1977-11-28 |
| AR210265A1 (es) | 1977-07-15 |
| ATA431175A (de) | 1977-06-15 |
| JPS516958A (en) | 1976-01-20 |
| SE7505482L (sv) | 1975-12-08 |
| NL7504921A (nl) | 1975-12-09 |
| AR207152A1 (es) | 1976-09-15 |
| DK135808B (da) | 1977-06-27 |
| NO751989L (cg-RX-API-DMAC10.html) | 1975-12-09 |
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