IN228043B - - Google Patents
Info
- Publication number
- IN228043B IN228043B IN3350DE2005A IN228043B IN 228043 B IN228043 B IN 228043B IN 3350DE2005 A IN3350DE2005 A IN 3350DE2005A IN 228043 B IN228043 B IN 228043B
- Authority
- IN
- India
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03003495 | 2003-02-14 | ||
| EP03007594 | 2003-04-02 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IN2005DE03350A IN2005DE03350A (en:Method) | 2007-06-01 |
| IN228043B true IN228043B (en:Method) | 2009-02-13 |
Family
ID=32870763
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN3350DE2005 IN228043B (en:Method) | 2003-02-14 | 2004-02-06 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20060229353A1 (en:Method) |
| EP (1) | EP1597262B1 (en:Method) |
| JP (1) | JP4795931B2 (en:Method) |
| KR (1) | KR20050098928A (en:Method) |
| CN (1) | CN1845925B (en:Method) |
| AT (1) | ATE448232T1 (en:Method) |
| AU (1) | AU2004212296B2 (en:Method) |
| BR (1) | BRPI0407234A (en:Method) |
| CA (1) | CA2515940C (en:Method) |
| DE (1) | DE602004024037D1 (en:Method) |
| ES (1) | ES2336562T3 (en:Method) |
| IL (1) | IL169897A0 (en:Method) |
| IN (1) | IN228043B (en:Method) |
| MX (1) | MX272108B (en:Method) |
| WO (1) | WO2004071382A2 (en:Method) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1341414B1 (en) | 2000-11-16 | 2013-01-02 | The Regents of The University of California | Marine actinomycete taxon for drug and fermentation product discovery |
| US7176232B2 (en) | 2002-06-24 | 2007-02-13 | The Regents Of The University Of California | Salinosporamides and methods for use thereof |
| PL2441767T3 (pl) * | 2003-06-20 | 2015-11-30 | Univ California | Salinosporamidy i sposoby ich stosowania |
| AU2004253478A1 (en) | 2003-06-20 | 2005-01-13 | Nereus Pharmaceuticals, Inc. | Use of [3.2.0] heterocyclic compounds and analogs thereof for the treatment of cancer, inflammation and infectious diseases |
| WO2005099687A2 (en) * | 2004-04-09 | 2005-10-27 | President And Fellows Of Harvard College | Analogs of salinosporamide a |
| JP2007535559A (ja) * | 2004-04-30 | 2007-12-06 | ネレアス ファーマシューティカルズ インコーポレイテッド | [3.2.0]複素環式化合物及びその使用法 |
| US7579371B2 (en) | 2004-04-30 | 2009-08-25 | Nereus Pharmaceuticals, Inc. | Methods of using [3.2.0] heterocyclic compounds and analogs thereof |
| KR20070041742A (ko) * | 2004-07-12 | 2007-04-19 | 바이엘 크롭사이언스 아게 | 살진균제 및 살충제로서의 치환된 2-피롤리돈 유도체 |
| MX2007006526A (es) * | 2004-12-03 | 2007-09-19 | Dana Farber Cancer Inst Inc | Composiciones y metodos para tratamiento de enfermedades neoplasicas. |
| AU2005311572A1 (en) * | 2004-12-03 | 2006-06-08 | Nereus Pharmaceuticals, Inc. | Methods of using (3.2.0) heterocyclic compounds and analogs thereof |
| WO2006118973A2 (en) * | 2005-04-29 | 2006-11-09 | Nereus Pharmaceuticals, Inc. | Methods of using heterobyclic compounds for treatment of rectal cancer |
| US7465720B2 (en) | 2005-09-12 | 2008-12-16 | President And Fellows Of Harvard College | Proteasome inhibiting β-lactam compounds |
| MX2008012847A (es) | 2006-04-06 | 2008-10-13 | Nereus Pharmaceuticals Inc | Sintesis total de salinosporamida a y analogos de la misma. |
| WO2008095195A2 (en) | 2007-02-02 | 2008-08-07 | Nereus Pharmaceuticals, Inc. | Lyophilized formulations of salinosporamide a |
| WO2008137780A2 (en) * | 2007-05-04 | 2008-11-13 | Nereus Pharmaceuticals, Inc. | Use of [3.2.0] heterocyclic compounds and analogs thereof for treating infectious diseases |
| US8394816B2 (en) | 2007-12-07 | 2013-03-12 | Irene Ghobrial | Methods of using [3.2.0] heterocyclic compounds and analogs thereof in treating Waldenstrom's Macroglobulinemia |
| EP2088205A1 (en) | 2008-02-11 | 2009-08-12 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | PSMB10: A diagnosis marker and therapeutic target of chronic rejection. |
| NZ587985A (en) | 2008-03-07 | 2012-07-27 | Nereus Pharmaceuticals Inc | Total synthesis of salinosporamide a and analogs thereof |
| EP2276765A4 (en) | 2008-05-12 | 2011-10-19 | Nereus Pharmaceuticals Inc | SALINOSPORAMIDE DERIVATIVES AS PROTEASOMAL HEMMER |
| WO2010096574A1 (en) | 2009-02-20 | 2010-08-26 | Lisanti Michael P | A method of diagnosis or prognosis of a neoplasm comprising determining the level of expression of a protein in stromal cells adjacent to the neoplasm |
| US9126997B1 (en) | 2010-09-07 | 2015-09-08 | Northwestern University | Synergistic effect of glucocorticoid receptor agonists in combination with proteosome inhibitors for treating leukemia and myeloma |
| JP6251176B2 (ja) | 2011-10-28 | 2017-12-20 | ミレニアム ファーマシューティカルズ, インコーポレイテッドMillennium Pharmaceuticals, Inc. | Nae阻害物質に対する応答のバイオマーカー |
| US20150184246A1 (en) | 2011-11-11 | 2015-07-02 | Millennium Pharmaceuticals, Inc. | Biomarkers of response to proteasome inhibitors |
| WO2013112601A1 (en) | 2012-01-24 | 2013-08-01 | Millennium Pharmaceuticals, Inc. | Methods of treatment of cancer |
| US10085987B2 (en) | 2012-01-27 | 2018-10-02 | Thomas Jefferson University | MCT protein inhibitor-related prognostic and therapeutic methods |
| US10662477B2 (en) | 2012-10-01 | 2020-05-26 | Millennium Pharmaceuticals, Inc. | Biomarkers and methods to predict response to inhibitors and uses thereof |
| WO2014172627A1 (en) | 2013-04-19 | 2014-10-23 | Thomas Jefferson University | Caveolin-1 related methods for treating glioblastoma with temozolomide |
| EP3339291A1 (en) | 2016-12-22 | 2018-06-27 | Vita Api | Proteasome inhibiting ss-lactam prodrugs useful for the treatment of cancer and neurodegenerative disorders |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6335358B1 (en) * | 1995-04-12 | 2002-01-01 | President And Fellows Of Harvard College | Lactacystin analogs |
| EP1341414B1 (en) * | 2000-11-16 | 2013-01-02 | The Regents of The University of California | Marine actinomycete taxon for drug and fermentation product discovery |
-
2004
- 2004-02-06 BR BR0407234-0A patent/BRPI0407234A/pt not_active IP Right Cessation
- 2004-02-06 CA CA2515940A patent/CA2515940C/en not_active Expired - Fee Related
- 2004-02-06 KR KR1020057014935A patent/KR20050098928A/ko not_active Abandoned
- 2004-02-06 US US10/545,449 patent/US20060229353A1/en not_active Abandoned
- 2004-02-06 CN CN2004800093759A patent/CN1845925B/zh not_active Expired - Fee Related
- 2004-02-06 JP JP2006501755A patent/JP4795931B2/ja not_active Expired - Fee Related
- 2004-02-06 DE DE602004024037T patent/DE602004024037D1/de not_active Expired - Lifetime
- 2004-02-06 AU AU2004212296A patent/AU2004212296B2/en not_active Ceased
- 2004-02-06 ES ES04708731T patent/ES2336562T3/es not_active Expired - Lifetime
- 2004-02-06 WO PCT/EP2004/001097 patent/WO2004071382A2/en not_active Ceased
- 2004-02-06 IN IN3350DE2005 patent/IN228043B/en unknown
- 2004-02-06 AT AT04708731T patent/ATE448232T1/de not_active IP Right Cessation
- 2004-02-06 EP EP04708731A patent/EP1597262B1/en not_active Expired - Lifetime
- 2004-02-06 MX MXPA05008478 patent/MX272108B/es active IP Right Grant
-
2005
- 2005-07-26 IL IL169897A patent/IL169897A0/en unknown
-
2009
- 2009-01-08 US US12/350,696 patent/US20110015248A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP4795931B2 (ja) | 2011-10-19 |
| WO2004071382A2 (en) | 2004-08-26 |
| DE602004024037D1 (de) | 2009-12-24 |
| CN1845925B (zh) | 2010-11-03 |
| IN2005DE03350A (en:Method) | 2007-06-01 |
| WO2004071382A3 (en) | 2005-01-06 |
| EP1597262A2 (en) | 2005-11-23 |
| US20110015248A1 (en) | 2011-01-20 |
| ATE448232T1 (de) | 2009-11-15 |
| CN1845925A (zh) | 2006-10-11 |
| IL169897A0 (en) | 2007-07-04 |
| US20060229353A1 (en) | 2006-10-12 |
| AU2004212296A1 (en) | 2004-08-26 |
| KR20050098928A (ko) | 2005-10-12 |
| HK1096392A1 (en) | 2007-06-01 |
| EP1597262B1 (en) | 2009-11-11 |
| MX272108B (es) | 2009-11-25 |
| MXPA05008478A (es) | 2005-10-18 |
| CA2515940A1 (en) | 2004-08-26 |
| BRPI0407234A (pt) | 2006-01-31 |
| ES2336562T3 (es) | 2010-04-14 |
| JP2006517934A (ja) | 2006-08-03 |
| CA2515940C (en) | 2011-12-06 |
| AU2004212296B2 (en) | 2010-06-17 |