IN2015DN03962A - - Google Patents

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Publication number
IN2015DN03962A
IN2015DN03962A IN3962DEN2015A IN2015DN03962A IN 2015DN03962 A IN2015DN03962 A IN 2015DN03962A IN 3962DEN2015 A IN3962DEN2015 A IN 3962DEN2015A IN 2015DN03962 A IN2015DN03962 A IN 2015DN03962A
Authority
IN
India
Prior art keywords
mycobacterium
proteins
esx
secreted
tuberculosis
Prior art date
Application number
Other languages
English (en)
Inventor
Claus Aagaard
Ida Rosenkrands
Truc Thi Kim Thanh Hoang
Peter Andersen
Original Assignee
Statens Seruminstitut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Statens Seruminstitut filed Critical Statens Seruminstitut
Publication of IN2015DN03962A publication Critical patent/IN2015DN03962A/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
IN3962DEN2015 2012-10-23 2013-10-18 IN2015DN03962A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA201200653 2012-10-23
DKPA201200652 2012-10-23
DKPA201200654 2012-10-23
DKPA201300477 2013-08-23
PCT/DK2013/000070 WO2014063704A2 (en) 2012-10-23 2013-10-18 M. tuberculosis vaccines

Publications (1)

Publication Number Publication Date
IN2015DN03962A true IN2015DN03962A (zh) 2015-10-02

Family

ID=49679267

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3962DEN2015 IN2015DN03962A (zh) 2012-10-23 2013-10-18

Country Status (8)

Country Link
US (1) US9526773B2 (zh)
EP (1) EP2912056B1 (zh)
JP (1) JP6470179B2 (zh)
CN (1) CN104736555B (zh)
BR (1) BR112015009070A2 (zh)
IN (1) IN2015DN03962A (zh)
WO (1) WO2014063704A2 (zh)
ZA (1) ZA201503467B (zh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015104380A1 (en) 2014-01-09 2015-07-16 Transgene Sa Fusion of heterooligomeric mycobacterial antigens
JP2017513860A (ja) * 2014-04-24 2017-06-01 スタテンス セールム インスティトゥート 新規結核菌（ｍ．ｔｕｂｅｒｃｕｌｏｓｉｓ）ワクチン
AU2016333474A1 (en) * 2015-09-30 2018-03-22 Boehringer Ingelheim Vetmedica Gmbh Improved modular antigen transportation molecules and uses therof in animals
CN105218680B (zh) * 2015-10-21 2019-06-25 中山大学 一种用于诱导外周血单个核细胞产生细胞因子的结核分支杆菌融合蛋白
CN105218681B (zh) * 2015-10-21 2019-06-25 中山大学 一种用于诱导外周血单个核细胞产生结核特异性细胞因子的融合蛋白
CN105567660B (zh) * 2016-01-08 2018-11-20 中国人民解放军第四军医大学 一种大肠杆菌重组表达结核分枝杆菌Rv2837c活性蛋白的方法及其应用
US20200148729A1 (en) * 2016-05-21 2020-05-14 Infectious Disease Research Institute Compositions and Methods for Treating Secondary Tuberculosis and Nontuberculosis Mycobacterium Infections
AU2017280065B2 (en) 2016-06-22 2021-07-01 International Aids Vaccine Initiative, Inc. Recombinant cytomegalovirus vectors as vaccines for tuberculosis
ES2950436T3 (es) 2016-12-14 2023-10-10 Becton Dickinson Co Métodos y composiciones para obtener una valoración de tuberculosis en un sujeto
SG11201906313SA (en) * 2017-01-09 2019-08-27 Biomunex Pharmaceuticals A polypeptide linker for preparing multispecific antibodies
WO2019079155A1 (en) 2017-10-17 2019-04-25 International Aids Vaccine Initiative, Inc. CASSETTES OF ANTIGENS OF TUBERCULOSIS
KR20220032054A (ko) 2019-06-14 2022-03-15 스태튼스 세룸 인스티튜트 결핵 백신용 융합 단백질
EP4007600A4 (en) * 2019-08-01 2023-08-23 Trustees of Tufts College VACCINE COMPOSITIONS AND ANTIGEN SELECTION METHODS
CN110590958B (zh) * 2019-09-11 2021-04-13 中国人民解放军总医院第八医学中心 一种串联多肽及其在抗结核分枝杆菌的免疫保护中的应用
WO2023156676A1 (en) 2022-02-21 2023-08-24 Statens Serum Institut A novel cationic adjuvant composition
CN115184603B (zh) * 2022-06-30 2024-02-06 首都医科大学附属北京胸科医院 EspC蛋白在制备结核分枝杆菌分离或富集产品中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200002938T2 (tr) * 1998-04-07 2001-02-21 Corixa Corporation Mikrobakteri tüberküloz antijenlerinin füzyon proteinleri ve bunların kullanımı
ES2346043T3 (es) * 2002-04-05 2010-10-08 Institut Pasteur Identificacion de las regiones rd1 y rd5 asociadas con la virulencia que permite el desarrollo de vacunas mejoradas de m. bovis bcg y m. microti.
MX370744B (es) * 2009-04-24 2019-12-20 Una vacuna antituberculosis tb para evitar la reactivación.
WO2012057904A1 (en) 2010-10-27 2012-05-03 Infectious Disease Research Institute Mycobacterium tuberculosis antigens and combinations thereof having high seroreactivity

Also Published As

Publication number Publication date
WO2014063704A8 (en) 2015-07-30
JP6470179B2 (ja) 2019-02-13
JP2015536309A (ja) 2015-12-21
WO2014063704A2 (en) 2014-05-01
WO2014063704A3 (en) 2014-06-19
ZA201503467B (en) 2016-11-30
EP2912056B1 (en) 2020-02-12
US9526773B2 (en) 2016-12-27
CN104736555B (zh) 2019-06-21
CN104736555A (zh) 2015-06-24
BR112015009070A2 (pt) 2017-07-04
US20150290311A1 (en) 2015-10-15
EP2912056A2 (en) 2015-09-02

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