IN2015DN01197A - - Google Patents

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Publication number
IN2015DN01197A
IN2015DN01197A IN1197DEN2015A IN2015DN01197A IN 2015DN01197 A IN2015DN01197 A IN 2015DN01197A IN 1197DEN2015 A IN1197DEN2015 A IN 1197DEN2015A IN 2015DN01197 A IN2015DN01197 A IN 2015DN01197A
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IN
India
Prior art keywords
compounds
cse
lyase
benefit
conditions
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English (en)
Inventor
N Sergio G Dur
Justin Chapman
Simon G Sydserff
Srinivas G Rao
Gregory Stein
Original Assignee
Sova Pharmaceuticals Inc
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Application filed by Sova Pharmaceuticals Inc filed Critical Sova Pharmaceuticals Inc
Publication of IN2015DN01197A publication Critical patent/IN2015DN01197A/en

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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • C07D233/72—Two oxygen atoms, e.g. hydantoin
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    • C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/40—Oxygen atoms attached in positions 3 and 4, e.g. maltol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring

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  • Epidemiology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Toxicology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
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US10227314B2 (en) 2019-03-12
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RU2640418C2 (ru) 2018-01-09
CA2879986A1 (fr) 2014-01-30
AU2018200635B2 (en) 2019-07-04
JP2018172397A (ja) 2018-11-08
US9771339B2 (en) 2017-09-26
CA2879986C (fr) 2020-09-29
AU2018200635A1 (en) 2018-02-15
AR091858A1 (es) 2015-03-04
WO2014018569A1 (fr) 2014-01-30
JP2015530368A (ja) 2015-10-15
US20170334866A1 (en) 2017-11-23
US20150175561A1 (en) 2015-06-25
AU2013293089A1 (en) 2015-02-19
TW201406732A (zh) 2014-02-16
CN109748881A (zh) 2019-05-14
EP2877458A4 (fr) 2016-08-10
TWI606040B (zh) 2017-11-21
CN104684901A (zh) 2015-06-03
JP6407864B2 (ja) 2018-10-17
EP2877458A1 (fr) 2015-06-03
KR20150041634A (ko) 2015-04-16

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