IN2014DN09053A - - Google Patents

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Publication number
IN2014DN09053A
IN2014DN09053A IN9053DEN2014A IN2014DN09053A IN 2014DN09053 A IN2014DN09053 A IN 2014DN09053A IN 9053DEN2014 A IN9053DEN2014 A IN 9053DEN2014A IN 2014DN09053 A IN2014DN09053 A IN 2014DN09053A
Authority
IN
India
Prior art keywords
tetrahydrolactoylpterin
lactoylpterin
sepiapterin
reaction formula
good yield
Prior art date
Application number
Other languages
English (en)
Inventor
Hiroshi Yoshino
Taichi Komoda
Yuichi Shiro
Shunichi Murata
Shizuaki Murata
Yasuhiro Kuroda
Original Assignee
Shiratori Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shiratori Pharm filed Critical Shiratori Pharm
Publication of IN2014DN09053A publication Critical patent/IN2014DN09053A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Peptides Or Proteins (AREA)
IN9053DEN2014 2012-05-07 2013-05-07 IN2014DN09053A (enExample)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012105758 2012-05-07
JP2012247255 2012-11-09
PCT/JP2013/062817 WO2013168693A1 (ja) 2012-05-07 2013-05-07 セピアプテリン及びテトラヒドロラクトイルプテリンの製造法

Publications (1)

Publication Number Publication Date
IN2014DN09053A true IN2014DN09053A (enExample) 2015-05-22

Family

ID=49550728

Family Applications (1)

Application Number Title Priority Date Filing Date
IN9053DEN2014 IN2014DN09053A (enExample) 2012-05-07 2013-05-07

Country Status (8)

Country Link
US (1) US9181254B2 (enExample)
EP (1) EP2848619B1 (enExample)
JP (1) JP6084967B2 (enExample)
CN (1) CN104736539B (enExample)
ES (1) ES2681345T3 (enExample)
FR (1) FR25C1044I1 (enExample)
IN (1) IN2014DN09053A (enExample)
WO (1) WO2013168693A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102016544B (zh) * 2008-02-21 2013-12-11 帝国制药株式会社 皮肤上伤口敷料的环境模拟测量装置及其测量方法
JP5066756B2 (ja) 2010-04-22 2012-11-07 学校法人日本大学 脳機能障害予防・改善用の薬剤及び飲食物
JP6809781B2 (ja) * 2015-11-18 2021-01-06 白鳥製薬株式会社 プテリン誘導体又はその塩
CN110312721A (zh) * 2016-11-29 2019-10-08 显莎制药公司 墨蝶呤的多晶型物
WO2018102315A1 (en) * 2016-11-29 2018-06-07 Censa Pharmaceuticals Inc. Polymoprhs of sepiapterin and salts thereof
MX2020002271A (es) * 2017-09-01 2020-10-05 Ptc Therapeutics Mp Inc Composiciones farmaceuticas que comprenden sepiapterina y sus usos de las mismas.
CA3102105A1 (en) 2018-05-30 2019-12-05 Ptc Therapeutics Mp, Inc. Compositions and methods for increasing tetrahydrobiopterin plasma exposure
JP7778477B2 (ja) 2018-05-30 2025-12-02 ピーティーシー セラピューティクス エムピー，インコーポレイテッド セピアプテリンの薬学的に許容される塩
JP7502197B2 (ja) 2018-05-30 2024-06-18 ピーティーシー セラピューティクス エムピー，インコーポレイテッド セピアプテリン血漿曝露を増加させるための方法
LT4009978T (lt) 2019-08-05 2024-11-25 Ptc Therapeutics Mp, Inc. Sepiapterino ir jo metabolitų panaudojimas spinduliuotės poveikio gydymui
US12691119B2 (en) 2021-02-09 2026-07-28 Ptc Therapeutics Mp, Inc. Methods for treating covid-19 with sepiapterin
CN117088883B (zh) * 2022-12-05 2025-10-21 哈尔滨工业大学（深圳） 一种以Pd/Al2O3为催化剂连续加氢制备四氢叶酸的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4713454A (en) 1985-01-28 1987-12-15 Shiratori Pharmaceutical Co., Ltd. Preparation process of (6R)-tetrahydro-L-biopterin
JPS61172877A (ja) 1985-01-28 1986-08-04 Shiratori Seiyaku Kk （６ｒ）−テトラヒドロ−ｌ−バイオプテリンの製造方法
JP5184783B2 (ja) 2003-11-17 2013-04-17 バイオマリン ファーマシューティカル インコーポレイテッド テトラヒドロビオプテリン、及びテトラヒドロビオプテリン類似体の製造方法
JP2011011976A (ja) 2007-10-10 2011-01-20 Shiratori Pharmaceutical Co Ltd プテリジン化合物及びｌ−ビオプテリンの製造方法
JP5066756B2 (ja) 2010-04-22 2012-11-07 学校法人日本大学 脳機能障害予防・改善用の薬剤及び飲食物

Also Published As

Publication number Publication date
EP2848619B1 (en) 2018-07-11
US9181254B2 (en) 2015-11-10
EP2848619A4 (en) 2015-11-04
WO2013168693A1 (ja) 2013-11-14
EP2848619A1 (en) 2015-03-18
CN104736539B (zh) 2017-09-01
ES2681345T3 (es) 2018-09-12
FR25C1044I1 (fr) 2026-01-02
JP6084967B2 (ja) 2017-02-22
CN104736539A (zh) 2015-06-24
JPWO2013168693A1 (ja) 2016-01-07
US20150119574A1 (en) 2015-04-30

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