IN2014DN09026A - - Google Patents

Info

Publication number
IN2014DN09026A
IN2014DN09026A IN9026DEN2014A IN2014DN09026A IN 2014DN09026 A IN2014DN09026 A IN 2014DN09026A IN 9026DEN2014 A IN9026DEN2014 A IN 9026DEN2014A IN 2014DN09026 A IN2014DN09026 A IN 2014DN09026A
Authority
IN
India
Prior art keywords
easy
reaction
purified
preparation
appropriate
Prior art date
Application number
Other languages
English (en)
Inventor
Yanghui Guo
Hegeng Wei
Hua Bai
Yingqiu Wu
Yue Zhang
Junhui Zhou
Yili Ding
Lingwei Bai
Shibao Yang
Original Assignee
Zhejiang Hisun Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zhejiang Hisun Pharm Co Ltd filed Critical Zhejiang Hisun Pharm Co Ltd
Publication of IN2014DN09026A publication Critical patent/IN2014DN09026A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06—Aminosugars
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IN9026DEN2014 2012-04-02 2013-04-02 IN2014DN09026A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201210102415.0A CN103360439B (zh) 2012-04-02 2012-04-02 制备肝素五糖的新中间体及其制备方法
PCT/CN2013/073601 WO2013149576A1 (fr) 2012-04-02 2013-04-02 Préparation d'un nouvel intermédiaire de pentasaccharide d'héparine et son procédé de préparation

Publications (1)

Publication Number Publication Date
IN2014DN09026A true IN2014DN09026A (fr) 2015-05-22

Family

ID=49299997

Family Applications (1)

Application Number Title Priority Date Filing Date
IN9026DEN2014 IN2014DN09026A (fr) 2012-04-02 2013-04-02

Country Status (6)

Country Link
US (1) US9624315B2 (fr)
EP (1) EP2837635B1 (fr)
JP (1) JP2015514098A (fr)
CN (1) CN103360439B (fr)
IN (1) IN2014DN09026A (fr)
WO (1) WO2013149576A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102718808A (zh) * 2012-06-04 2012-10-10 浙江星月药物科技股份有限公司 一类多糖衍生物及其中间体的制备方法
CN103570774B (zh) * 2012-08-07 2017-08-25 博瑞生物医药（苏州）股份有限公司 一种戊糖化合物的纯化方法
CN103992364B (zh) * 2014-03-25 2016-08-10 南京天翔医药科技有限公司 一种磺达肝癸钠的分离提取方法
CN103965269B (zh) * 2014-04-16 2018-05-04 杭州华东医药集团新药研究院有限公司 低水分高纯度的磺达肝癸钠及其制备方法
CN104098618A (zh) * 2014-07-25 2014-10-15 河北常山生化药业股份有限公司 磺达肝癸钠中间体及其中间体和磺达肝癸钠的制备方法
CN105037452B (zh) * 2015-06-19 2018-10-09 天津红日药业股份有限公司 一种快速制备高纯度磺达肝癸钠的精制方法
EP3398971A4 (fr) * 2015-12-30 2019-09-25 Shenzhen Hepalink Pharmaceutical Group Co., Ltd. Oligosaccharide d'héparine sulfaté et procédé de préparation et application de celui-ci
CN108148101B (zh) * 2016-12-03 2021-12-24 烟台东诚药业集团股份有限公司 一种制备磺达肝癸钠的新工艺方法
CN115057896A (zh) * 2022-07-28 2022-09-16 苏州柯默拓医药科技有限公司 一种磺达肝癸钠的合成方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4818816A (en) * 1981-04-28 1989-04-04 Choay, S.A. Process for the organic synthesis of oligosaccharides and derivatives thereof
EP0300099A1 (fr) 1987-07-20 1989-01-25 Akzo N.V. Pentasaccharides
US7541445B2 (en) * 2001-09-07 2009-06-02 Alchemia Limited Synthetic heparin pentasaccharides
WO2010037179A1 (fr) * 2008-10-03 2010-04-08 Glycan Biosciences Pty Ltd Conjugués anioniques d’un métabolite bactérien glycosylé
ES2336297B1 (es) 2008-10-08 2011-01-24 Laboratorios Farmaceuticos Rovi, S.A. Procedimiento de sintesis de pentasacaridos desprotegidos a partir deun pentasacarido precursos protegido.
JP2012106933A (ja) * 2009-03-10 2012-06-07 Univ Of Tokyo オリゴアミノ糖化合物
EP2464668B1 (fr) * 2009-07-31 2022-12-07 Reliable Biopharmaceutical Corporation Procédé de préparation de fondaparinux sodique et intermédiaires utiles pour sa synthèse
CN102718808A (zh) * 2012-06-04 2012-10-10 浙江星月药物科技股份有限公司 一类多糖衍生物及其中间体的制备方法

Also Published As

Publication number Publication date
EP2837635B1 (fr) 2017-10-18
EP2837635A1 (fr) 2015-02-18
JP2015514098A (ja) 2015-05-18
CN103360439B (zh) 2017-12-15
US9624315B2 (en) 2017-04-18
CN103360439A (zh) 2013-10-23
EP2837635A4 (fr) 2015-05-27
US20150299340A1 (en) 2015-10-22
WO2013149576A1 (fr) 2013-10-10

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