IN2014DN08970A - - Google Patents
Info
- Publication number
- IN2014DN08970A IN2014DN08970A IN8970DEN2014A IN2014DN08970A IN 2014DN08970 A IN2014DN08970 A IN 2014DN08970A IN 8970DEN2014 A IN8970DEN2014 A IN 8970DEN2014A IN 2014DN08970 A IN2014DN08970 A IN 2014DN08970A
- Authority
- IN
- India
- Prior art keywords
- pi3k
- assaying
- subunit
- mutation
- catalytic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261617284P | 2012-03-29 | 2012-03-29 | |
| US201361767848P | 2013-02-22 | 2013-02-22 | |
| PCT/EP2013/056600 WO2013144249A1 (en) | 2012-03-29 | 2013-03-27 | Pharmaceutical diagnostic |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN08970A true IN2014DN08970A (zh) | 2015-05-22 |
Family
ID=48083130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN8970DEN2014 IN2014DN08970A (zh) | 2012-03-29 | 2013-03-27 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US9795596B2 (zh) |
| EP (1) | EP2830621B1 (zh) |
| JP (1) | JP6224067B2 (zh) |
| KR (1) | KR20140138771A (zh) |
| CN (1) | CN104271136A (zh) |
| AR (1) | AR090544A1 (zh) |
| AU (1) | AU2013241752B2 (zh) |
| BR (1) | BR112014023530A2 (zh) |
| CA (1) | CA2866127A1 (zh) |
| CL (1) | CL2014002576A1 (zh) |
| CO (1) | CO7091176A2 (zh) |
| EA (1) | EA028984B1 (zh) |
| EC (1) | ECSP14025016A (zh) |
| ES (1) | ES2845560T3 (zh) |
| GT (1) | GT201400206A (zh) |
| HK (1) | HK1200723A1 (zh) |
| IL (1) | IL234658B (zh) |
| IN (1) | IN2014DN08970A (zh) |
| MX (1) | MX2014011682A (zh) |
| NZ (1) | NZ628596A (zh) |
| PH (1) | PH12014502168A1 (zh) |
| SG (2) | SG10201608001RA (zh) |
| TW (1) | TW201345525A (zh) |
| WO (1) | WO2013144249A1 (zh) |
| ZA (1) | ZA201405938B (zh) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2015144019A (ru) * | 2013-03-15 | 2017-04-24 | Новартис Аг | Биомаркеры фармакодинамического ответа опухоли |
| EP3842554B1 (en) * | 2014-05-09 | 2022-12-14 | Memorial Sloan Kettering Cancer Center | Biomarkers for response to pi3k inhibitors |
| PL3200772T3 (pl) * | 2014-10-03 | 2022-12-19 | Novartis Ag | Kompozycje farmaceutyczne zawierające alpelisyb |
| AU2016362683B2 (en) * | 2015-12-03 | 2019-11-07 | Novartis Ag | Treatment of cancer with a PI3K inhibitor in a patient preselected for having a PIK3CA mutation in the ctDNA |
| US20230270855A1 (en) * | 2018-04-09 | 2023-08-31 | The Research Foundation for The State of University New york | Genetically Modified T-Cells and PI3K/AKT Inhibitors For Cancer Treatment |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| DE68908054T2 (de) | 1988-01-21 | 1994-03-10 | Genentech Inc | Verstärkung und nachweis von nukleinsäuresequenzen. |
| CA1340807C (en) | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
| US5130238A (en) | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
| WO1990001069A1 (en) | 1988-07-20 | 1990-02-08 | Segev Diagnostics, Inc. | Process for amplifying and detecting nucleic acid sequences |
| US5169766A (en) | 1991-06-14 | 1992-12-08 | Life Technologies, Inc. | Amplification of nucleic acid molecules |
| US5846717A (en) | 1996-01-24 | 1998-12-08 | Third Wave Technologies, Inc. | Detection of nucleic acid sequences by invader-directed cleavage |
| US5605798A (en) | 1993-01-07 | 1997-02-25 | Sequenom, Inc. | DNA diagnostic based on mass spectrometry |
| GB2453173A (en) | 2007-09-28 | 2009-04-01 | Dxs Ltd | Polynucleotide primers |
| CA2730271A1 (en) * | 2008-07-07 | 2010-01-14 | Xcovery Holding Company Llc | Pi3k isoform selective inhibitors |
| UA104147C2 (uk) * | 2008-09-10 | 2014-01-10 | Новартис Аг | Похідна піролідиндикарбонової кислоти та її застосування у лікуванні проліферативних захворювань |
| CN101445832B (zh) | 2008-12-23 | 2011-09-14 | 广州益善生物技术有限公司 | Pik3ca基因突变的检测探针、液相芯片及其检测方法 |
| AR082418A1 (es) * | 2010-08-02 | 2012-12-05 | Novartis Ag | Formas cristalinas de 1-(4-metil-5-[2-(2,2,2-trifluoro-1,1-dimetil-etil)-piridin-4-il]-tiazol-2-il)-amida de 2-amida del acido (s)-pirrolidin-1,2-dicarboxilico |
-
2013
- 2013-03-27 BR BR112014023530A patent/BR112014023530A2/pt not_active IP Right Cessation
- 2013-03-27 SG SG10201608001RA patent/SG10201608001RA/en unknown
- 2013-03-27 CN CN201380017393.0A patent/CN104271136A/zh active Pending
- 2013-03-27 IN IN8970DEN2014 patent/IN2014DN08970A/en unknown
- 2013-03-27 EA EA201491787A patent/EA028984B1/ru not_active IP Right Cessation
- 2013-03-27 EP EP13715169.2A patent/EP2830621B1/en active Active
- 2013-03-27 CA CA 2866127 patent/CA2866127A1/en not_active Abandoned
- 2013-03-27 ES ES13715169T patent/ES2845560T3/es active Active
- 2013-03-27 AU AU2013241752A patent/AU2013241752B2/en not_active Ceased
- 2013-03-27 US US14/387,653 patent/US9795596B2/en active Active
- 2013-03-27 WO PCT/EP2013/056600 patent/WO2013144249A1/en active Application Filing
- 2013-03-27 MX MX2014011682A patent/MX2014011682A/es unknown
- 2013-03-27 AR ARP130101029 patent/AR090544A1/es unknown
- 2013-03-27 KR KR1020147026735A patent/KR20140138771A/ko not_active Application Discontinuation
- 2013-03-27 JP JP2015502341A patent/JP6224067B2/ja active Active
- 2013-03-27 SG SG11201405169SA patent/SG11201405169SA/en unknown
- 2013-03-27 NZ NZ628596A patent/NZ628596A/en not_active IP Right Cessation
- 2013-03-28 TW TW102111262A patent/TW201345525A/zh unknown
-
2014
- 2014-08-13 ZA ZA2014/05938A patent/ZA201405938B/en unknown
- 2014-09-15 IL IL234658A patent/IL234658B/en not_active IP Right Cessation
- 2014-09-26 CL CL2014002576A patent/CL2014002576A1/es unknown
- 2014-09-26 PH PH12014502168A patent/PH12014502168A1/en unknown
- 2014-09-29 CO CO14215143A patent/CO7091176A2/es unknown
- 2014-09-29 GT GT201400206A patent/GT201400206A/es unknown
- 2014-10-29 EC ECIEPI201425016A patent/ECSP14025016A/es unknown
-
2015
- 2015-02-05 HK HK15101259.7A patent/HK1200723A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2845560T3 (es) | 2021-07-27 |
| TW201345525A (zh) | 2013-11-16 |
| US20150111927A1 (en) | 2015-04-23 |
| MX2014011682A (es) | 2015-01-22 |
| CO7091176A2 (es) | 2014-10-21 |
| EA028984B1 (ru) | 2018-01-31 |
| CA2866127A1 (en) | 2013-10-03 |
| AU2013241752B2 (en) | 2016-07-07 |
| JP6224067B2 (ja) | 2017-11-01 |
| CL2014002576A1 (es) | 2015-01-23 |
| WO2013144249A1 (en) | 2013-10-03 |
| ECSP14025016A (es) | 2015-09-30 |
| IL234658B (en) | 2018-02-28 |
| CN104271136A (zh) | 2015-01-07 |
| GT201400206A (es) | 2017-09-28 |
| PH12014502168A1 (en) | 2014-12-10 |
| AU2013241752A1 (en) | 2014-09-25 |
| SG11201405169SA (en) | 2014-10-30 |
| EA201491787A1 (ru) | 2015-01-30 |
| ZA201405938B (en) | 2015-11-25 |
| SG10201608001RA (en) | 2016-11-29 |
| EP2830621B1 (en) | 2020-10-21 |
| JP2015514080A (ja) | 2015-05-18 |
| KR20140138771A (ko) | 2014-12-04 |
| BR112014023530A2 (pt) | 2017-07-18 |
| US9795596B2 (en) | 2017-10-24 |
| NZ628596A (en) | 2015-10-30 |
| AR090544A1 (es) | 2014-11-19 |
| HK1200723A1 (zh) | 2015-08-14 |
| EP2830621A1 (en) | 2015-02-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB2557499B (en) | Oxygen reduction reaction catalyst | |
| SG10201710049RA (en) | Compositions, methods and systems for polymerase chain reaction assays | |
| PH12014502168A1 (en) | Pharmaceutical diagnostic | |
| BR112012001372A2 (pt) | comprimido, e, métodos para preparar um comprimido e para a profilaxia ou tratamento de hiperfosfatemia. | |
| EP4332839A3 (en) | Population pharmacokinetics tools and uses thereof | |
| PH12016502291A1 (en) | Indolizine derivatives as phosphoinositide 3-kinases inhibitors | |
| WO2015017537A3 (en) | Colorectal cancer recurrence gene expression signature | |
| HK1204474A1 (zh) | 用於治療癌症，自身免疫炎症和中樞神經系統障礙的雙氟二氧戊環氨基苯並咪唑激酶抑制劑 | |
| EP3037826A4 (en) | Microchemical chip and reaction device | |
| EP2864919C0 (en) | SYSTEMS AND METHODS FOR GENERATING BIOMARRKER SIGNATURES WITH INTEGRATED DOUBLE ENSEMBLE AND GENERALIZED SIMULATED ANNEALING TECHNIQUES | |
| TWD176632S (zh) | 輪圈之部分 | |
| MX2019010098A (es) | Antiandrogenos para el tratamiento del cancer de prostata resistente a la castracion no metastasico. | |
| UA112760C2 (uk) | Теобромін у комбінації з гвайфенезином для лікування кашлю | |
| MY164628A (en) | Catalytic cracking catalyst | |
| PH12014502109A1 (en) | Methods of treating cancer using aurora kinase inhibitors | |
| MX2015013197A (es) | Biomarcadores de la respuesta farmacodinamica tumoral. | |
| MY182547A (en) | Polymerase chain reaction detection system | |
| BR112017006732A2 (pt) | enxofre como um oxidante seletivo no processamento de hidrocarboneto oxidativo em catalisadores de óxido/calcogeneto | |
| TN2017000174A1 (en) | Low dosage a2a antagonist for the treatment of adhd and parkinsons | |
| TN2014000370A1 (en) | Pharmaceutical diagnostic | |
| AP2015008957A0 (en) | Production of biomass for use in the treatment of fischer-tropsch reaction water | |
| WO2014201446A3 (en) | Use of hydrogen sulfide synthesis inhibitors for the therapy of colorectal cancers | |
| GB201212690D0 (en) | Materials and methods for treating pten mutated or deficient cancer | |
| FR2987047B1 (fr) | Utilisations des derives de carbazolophenones pour le traitement du cancer. | |
| TWD176508S (zh) | 生化反應器之面板之部分 |