IN2014DN03077A - - Google Patents
Info
- Publication number
- IN2014DN03077A IN2014DN03077A IN3077DEN2014A IN2014DN03077A IN 2014DN03077 A IN2014DN03077 A IN 2014DN03077A IN 3077DEN2014 A IN3077DEN2014 A IN 3077DEN2014A IN 2014DN03077 A IN2014DN03077 A IN 2014DN03077A
- Authority
- IN
- India
- Prior art keywords
- sirt2
- methods
- assay
- practicing
- kits
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/38—Amides of thiocarboxylic acids
- C07C327/40—Amides of thiocarboxylic acids having carbon atoms of thiocarboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C327/42—Amides of thiocarboxylic acids having carbon atoms of thiocarboxamide groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of a saturated carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161544452P | 2011-10-07 | 2011-10-07 | |
| PCT/US2012/058846 WO2013052727A1 (en) | 2011-10-07 | 2012-10-05 | Methods of treatment using modulators of sirt2 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN03077A true IN2014DN03077A (enExample) | 2015-05-15 |
Family
ID=48044173
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN3077DEN2014 IN2014DN03077A (enExample) | 2011-10-07 | 2012-10-05 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US9359293B2 (enExample) |
| EP (1) | EP2763962B1 (enExample) |
| CN (2) | CN103974934B (enExample) |
| ES (1) | ES2773266T3 (enExample) |
| IN (1) | IN2014DN03077A (enExample) |
| WO (1) | WO2013052727A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103974934B (zh) * | 2011-10-07 | 2019-07-23 | 康奈尔大学 | 使用sirt2调节剂的治疗方法 |
| WO2014149196A1 (en) * | 2013-03-22 | 2014-09-25 | University Of Florida Research Foundation, Inc. | Polymer nanocomposites for early diagnosis of diseases |
| US10556878B2 (en) * | 2013-06-06 | 2020-02-11 | Cornell University | Thiourea compounds and their use as inhibitors of Sirt2 or Sirt5 |
| WO2018144864A1 (en) * | 2017-02-03 | 2018-08-09 | The Mclean Hospital Corporation | Methods for manipulating cell fate |
| CN110551048B (zh) * | 2018-06-04 | 2021-08-10 | 中国科学院上海药物研究所 | 一类sirt2抑制剂、其制备方法及用途 |
| US12161639B2 (en) | 2018-07-17 | 2024-12-10 | University of Pittsburgh—of the Commonwealth System of Higher Education | Methods of treating PACS1 and PACS2 syndromes |
| CN114315670B (zh) * | 2022-01-19 | 2024-03-29 | 贵州医科大学 | 一种sirt2/hdac6双靶标抑制剂及其应用 |
| CN116178340B (zh) * | 2023-04-28 | 2023-08-18 | 细胞生态海河实验室 | 一种protac化合物、制备方法及药物组合物 |
| WO2026125700A1 (de) * | 2024-12-13 | 2026-06-18 | Heinrich-Heine-Universität Düsseldorf | Zielgerichtete therapie von krebs durch pharmakologische aktivierung von mtor |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10063008A1 (de) * | 2000-12-16 | 2002-06-20 | Merck Patent Gmbh | Carbonsäureamidderivate |
| EP1697337A2 (en) | 2003-12-22 | 2006-09-06 | Astellas Pharma Inc. | Ornithine derivatives as prostaglandin-e2-agonists or antagonists |
| US20070021434A1 (en) | 2005-06-24 | 2007-01-25 | Migenix Inc. | Non-nucleoside anti-hepacivirus agents and uses thereof |
| US20080171783A1 (en) | 2006-12-28 | 2008-07-17 | Migenix Inc. | Compositions and methods for treating hyperproliferative disease |
| CN103974934B (zh) * | 2011-10-07 | 2019-07-23 | 康奈尔大学 | 使用sirt2调节剂的治疗方法 |
-
2012
- 2012-10-05 CN CN201280059788.2A patent/CN103974934B/zh not_active Expired - Fee Related
- 2012-10-05 WO PCT/US2012/058846 patent/WO2013052727A1/en not_active Ceased
- 2012-10-05 ES ES12838058T patent/ES2773266T3/es active Active
- 2012-10-05 US US14/349,140 patent/US9359293B2/en active Active
- 2012-10-05 IN IN3077DEN2014 patent/IN2014DN03077A/en unknown
- 2012-10-05 EP EP12838058.1A patent/EP2763962B1/en active Active
- 2012-10-05 CN CN201910002021.XA patent/CN110143900B/zh not_active Expired - Fee Related
-
2016
- 2016-06-03 US US15/172,756 patent/US9572789B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2763962A1 (en) | 2014-08-13 |
| EP2763962B1 (en) | 2019-12-04 |
| US20140249216A1 (en) | 2014-09-04 |
| ES2773266T3 (es) | 2020-07-10 |
| CN103974934A (zh) | 2014-08-06 |
| US20160279091A1 (en) | 2016-09-29 |
| CN103974934B (zh) | 2019-07-23 |
| US9359293B2 (en) | 2016-06-07 |
| CN110143900A (zh) | 2019-08-20 |
| US9572789B2 (en) | 2017-02-21 |
| CN110143900B (zh) | 2021-08-03 |
| WO2013052727A1 (en) | 2013-04-11 |
| EP2763962A4 (en) | 2015-08-19 |
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