IN2014DN03077A - - Google Patents
Info
- Publication number
- IN2014DN03077A IN2014DN03077A IN3077DEN2014A IN2014DN03077A IN 2014DN03077 A IN2014DN03077 A IN 2014DN03077A IN 3077DEN2014 A IN3077DEN2014 A IN 3077DEN2014A IN 2014DN03077 A IN2014DN03077 A IN 2014DN03077A
- Authority
- IN
- India
- Prior art keywords
- sirt2
- methods
- assay
- practicing
- kits
- Prior art date
Links
- 102000000477 Sirtuin 2 Human genes 0.000 abstract 2
- 108010041216 Sirtuin 2 Proteins 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/38—Amides of thiocarboxylic acids
- C07C327/40—Amides of thiocarboxylic acids having carbon atoms of thiocarboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C327/42—Amides of thiocarboxylic acids having carbon atoms of thiocarboxamide groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of a saturated carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161544452P | 2011-10-07 | 2011-10-07 | |
| PCT/US2012/058846 WO2013052727A1 (en) | 2011-10-07 | 2012-10-05 | Methods of treatment using modulators of sirt2 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN03077A true IN2014DN03077A (enrdf_load_stackoverflow) | 2015-05-15 |
Family
ID=48044173
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN3077DEN2014 IN2014DN03077A (enrdf_load_stackoverflow) | 2011-10-07 | 2012-10-05 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US9359293B2 (enrdf_load_stackoverflow) |
| EP (1) | EP2763962B1 (enrdf_load_stackoverflow) |
| CN (2) | CN110143900B (enrdf_load_stackoverflow) |
| ES (1) | ES2773266T3 (enrdf_load_stackoverflow) |
| IN (1) | IN2014DN03077A (enrdf_load_stackoverflow) |
| WO (1) | WO2013052727A1 (enrdf_load_stackoverflow) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2773266T3 (es) * | 2011-10-07 | 2020-07-10 | Univ Cornell | Métodos de tratamiento utilizando moduladores de SIRT2 |
| US9945865B2 (en) * | 2013-03-22 | 2018-04-17 | University Of Florida Research Foundation, Inc. | Polymer nanocomposites for early diagnosis of diseases |
| WO2014197775A1 (en) * | 2013-06-06 | 2014-12-11 | Cornell University | Thiourea compounds and their use as inhibitors of sirt2 or sirt5 |
| JP2020506707A (ja) * | 2017-02-03 | 2020-03-05 | ザ マクリーン ホスピタル コーポレーション | 細胞の運命を操作するための方法 |
| CN110551048B (zh) * | 2018-06-04 | 2021-08-10 | 中国科学院上海药物研究所 | 一类sirt2抑制剂、其制备方法及用途 |
| WO2020018647A1 (en) | 2018-07-17 | 2020-01-23 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Methods of treating pacs1 and pacs2 syndromes |
| CN114315670B (zh) * | 2022-01-19 | 2024-03-29 | 贵州医科大学 | 一种sirt2/hdac6双靶标抑制剂及其应用 |
| CN116178340B (zh) * | 2023-04-28 | 2023-08-18 | 细胞生态海河实验室 | 一种protac化合物、制备方法及药物组合物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10063008A1 (de) * | 2000-12-16 | 2002-06-20 | Merck Patent Gmbh | Carbonsäureamidderivate |
| CA2550958A1 (en) | 2003-12-22 | 2005-07-07 | Astellas Pharma Inc. | Ornithine derivatives as prostaglandin e2 agonists or antagonists |
| WO2007002639A2 (en) | 2005-06-24 | 2007-01-04 | Migenix Inc. | Non-nucleoside anti-hepacivirus agents and uses thereof |
| US20080171783A1 (en) | 2006-12-28 | 2008-07-17 | Migenix Inc. | Compositions and methods for treating hyperproliferative disease |
| ES2773266T3 (es) * | 2011-10-07 | 2020-07-10 | Univ Cornell | Métodos de tratamiento utilizando moduladores de SIRT2 |
-
2012
- 2012-10-05 ES ES12838058T patent/ES2773266T3/es active Active
- 2012-10-05 CN CN201910002021.XA patent/CN110143900B/zh active Active
- 2012-10-05 CN CN201280059788.2A patent/CN103974934B/zh active Active
- 2012-10-05 IN IN3077DEN2014 patent/IN2014DN03077A/en unknown
- 2012-10-05 WO PCT/US2012/058846 patent/WO2013052727A1/en active Application Filing
- 2012-10-05 EP EP12838058.1A patent/EP2763962B1/en active Active
- 2012-10-05 US US14/349,140 patent/US9359293B2/en active Active
-
2016
- 2016-06-03 US US15/172,756 patent/US9572789B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US9359293B2 (en) | 2016-06-07 |
| US9572789B2 (en) | 2017-02-21 |
| CN103974934B (zh) | 2019-07-23 |
| EP2763962A4 (en) | 2015-08-19 |
| ES2773266T3 (es) | 2020-07-10 |
| CN103974934A (zh) | 2014-08-06 |
| US20140249216A1 (en) | 2014-09-04 |
| WO2013052727A1 (en) | 2013-04-11 |
| CN110143900B (zh) | 2021-08-03 |
| CN110143900A (zh) | 2019-08-20 |
| US20160279091A1 (en) | 2016-09-29 |
| EP2763962A1 (en) | 2014-08-13 |
| EP2763962B1 (en) | 2019-12-04 |
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