IN2014CN04734A - - Google Patents
Info
- Publication number
- IN2014CN04734A IN2014CN04734A IN4734CHN2014A IN2014CN04734A IN 2014CN04734 A IN2014CN04734 A IN 2014CN04734A IN 4734CHN2014 A IN4734CHN2014 A IN 4734CHN2014A IN 2014CN04734 A IN2014CN04734 A IN 2014CN04734A
- Authority
- IN
- India
- Prior art keywords
- cells
- vectors
- compositions
- biologically active
- provides
- Prior art date
Links
- 108091032973 (ribonucleotides)n+m Proteins 0.000 abstract 5
- 239000013598 vector Substances 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 3
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 102000040650 (ribonucleotides)n+m Human genes 0.000 abstract 1
- 102000007474 Multiprotein Complexes Human genes 0.000 abstract 1
- 108010085220 Multiprotein Complexes Proteins 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000014509 gene expression Effects 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 239000012096 transfection reagent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/85—Fusion polypeptide containing an RNA binding domain
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
- C12N2320/32—Special delivery means, e.g. tissue-specific
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2330/00—Production
- C12N2330/50—Biochemical production, i.e. in a transformed host cell
- C12N2330/51—Specially adapted vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/48—Vector systems having a special element relevant for transcription regulating transport or export of RNA, e.g. RRE, PRE, WPRE, CTE
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161579815P | 2011-12-23 | 2011-12-23 | |
| PCT/US2012/071576 WO2013096958A1 (en) | 2011-12-23 | 2012-12-24 | Compositions and methods for the delivery of biologically active rnas |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014CN04734A true IN2014CN04734A (enrdf_load_stackoverflow) | 2015-09-18 |
Family
ID=48654938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN4734CHN2014 IN2014CN04734A (enrdf_load_stackoverflow) | 2011-12-23 | 2012-12-24 |
Country Status (10)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11639371B2 (en) * | 2016-02-17 | 2023-05-02 | The Chinese University Of Hong Kong | Peptidylic inhibitors of nucleolin (NCL) targeting CAG-repeat RNA toxicity and methods for reducing polyQ-mediated toxicity in polyQ diseases |
| WO2018132755A1 (en) * | 2017-01-12 | 2018-07-19 | Duke University | Compositions and methods for disrupting the molecular mechanisms associated with mitochondrial dysfunction and neurodegenerative disease |
| EP3645012A4 (en) * | 2017-06-28 | 2021-06-30 | University Of South Florida | MODIFIED UBE3A GENE FOR A GENE THERAPY APPROACH FOR ANGELMAN SYNDROME |
| EP3908328A1 (en) * | 2019-01-10 | 2021-11-17 | BioNTech RNA Pharmaceuticals GmbH | Localized administration of rna molecules for therapy |
| CN114040774A (zh) * | 2019-02-15 | 2022-02-11 | 阿特雷卡公司 | 结合肿瘤组织用于诊断和治疗的抗体 |
| CN114807194B (zh) * | 2020-08-31 | 2023-05-12 | 南京工业大学 | 一种提高梭菌中蛋白表达效率的方法 |
| CA3218711A1 (en) * | 2021-05-13 | 2022-11-17 | Roee Amit | Methods and compositions for treatment of viral infection |
| WO2023182870A1 (ko) * | 2022-03-24 | 2023-09-28 | (주)셀레브레인 | 신규 재조합 벡터 및 이의 용도 |
| EP4303305A1 (en) * | 2022-07-07 | 2024-01-10 | Kutzner, Christoph | Fusion polypeptides for cell penetration and cell targeting |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5585263A (en) * | 1994-05-20 | 1996-12-17 | University Of Alabama At Birmingham Research Foundation | Purified retroviral constitutive transport enhancer and its use to facilitate mRNA transport, and to produce recombinant, attenuated HIV |
| EP1540004A4 (en) * | 2002-07-31 | 2007-10-03 | Nucleonics Inc | DOUBLE-STRING RNA STRUCTURES AND CONSTRUCTS AND METHOD FOR THE PRODUCTION AND USE THEREOF |
| WO2004028471A2 (en) * | 2002-09-28 | 2004-04-08 | Massachusetts Institute Of Technology | Influenza therapeutic |
| WO2009002462A1 (en) * | 2007-06-22 | 2008-12-31 | The Board Of Trustees Of The Leland Stanford Junior University | Pre-mirna loop-modulated target regulation |
| KR20110128345A (ko) * | 2009-03-13 | 2011-11-29 | 에젠, 인코포레이티드 | 생물학적 활성 ｒｎａ의 전달을 위한 조성물 및 방법 |
| PL2539451T3 (pl) * | 2010-02-24 | 2016-08-31 | Arrowhead Res Corporation | Kompozycje do ukierunkowanego dostarczania siRNA |
-
2012
- 2012-12-24 JP JP2014549001A patent/JP2015507474A/ja active Pending
- 2012-12-24 IN IN4734CHN2014 patent/IN2014CN04734A/en unknown
- 2012-12-24 WO PCT/US2012/071576 patent/WO2013096958A1/en active Application Filing
- 2012-12-24 KR KR1020147020750A patent/KR20140123054A/ko not_active Withdrawn
- 2012-12-24 HK HK15103893.5A patent/HK1203548A1/xx unknown
- 2012-12-24 EP EP12859768.9A patent/EP2794879A4/en not_active Withdrawn
- 2012-12-24 AU AU2012358181A patent/AU2012358181A1/en not_active Abandoned
- 2012-12-24 CN CN201280070535.5A patent/CN104169419A/zh active Pending
- 2012-12-24 CA CA2860228A patent/CA2860228A1/en not_active Abandoned
- 2012-12-24 US US13/726,337 patent/US20130164845A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2860228A1 (en) | 2013-06-27 |
| JP2015507474A (ja) | 2015-03-12 |
| CN104169419A (zh) | 2014-11-26 |
| WO2013096958A1 (en) | 2013-06-27 |
| HK1203548A1 (en) | 2015-10-30 |
| AU2012358181A8 (en) | 2015-06-18 |
| EP2794879A1 (en) | 2014-10-29 |
| EP2794879A4 (en) | 2015-10-14 |
| WO2013096958A8 (en) | 2014-07-24 |
| KR20140123054A (ko) | 2014-10-21 |
| US20130164845A1 (en) | 2013-06-27 |
| AU2012358181A1 (en) | 2014-07-10 |
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