IN2014CH00518A - - Google Patents

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Publication number
IN2014CH00518A
IN2014CH00518A IN518CH2014A IN2014CH00518A IN 2014CH00518 A IN2014CH00518 A IN 2014CH00518A IN 518CH2014 A IN518CH2014 A IN 518CH2014A IN 2014CH00518 A IN2014CH00518 A IN 2014CH00518A
Authority
IN
India
Prior art keywords
formula
compound
bzo
deoxy
fluoro
Prior art date
Application number
Other languages
English (en)
Inventor
Thirumalai Rajan Srinivasan
Kishore Kumar Muppa
Srinivas Rao Nimmala
Original Assignee
Msn Lab Private Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Msn Lab Private Ltd filed Critical Msn Lab Private Ltd
Priority to IN518CH2014 priority Critical patent/IN2014CH00518A/en
Priority to PCT/IN2015/000068 priority patent/WO2015118558A2/fr
Publication of IN2014CH00518A publication Critical patent/IN2014CH00518A/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Saccharide Compounds (AREA)
IN518CH2014 2014-02-04 2015-02-04 IN2014CH00518A (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IN518CH2014 IN2014CH00518A (fr) 2014-02-04 2015-02-04
PCT/IN2015/000068 WO2015118558A2 (fr) 2014-02-04 2015-02-04 Procédé pour la préparation de clofarabine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN518CH2014 IN2014CH00518A (fr) 2014-02-04 2015-02-04

Publications (1)

Publication Number Publication Date
IN2014CH00518A true IN2014CH00518A (fr) 2015-08-07

Family

ID=53778571

Family Applications (1)

Application Number Title Priority Date Filing Date
IN518CH2014 IN2014CH00518A (fr) 2014-02-04 2015-02-04

Country Status (2)

Country Link
IN (1) IN2014CH00518A (fr)
WO (1) WO2015118558A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105601688A (zh) * 2015-12-23 2016-05-25 国药一心制药有限公司 一种氯法拉滨中间体及氯法拉滨的制备方法
CN106397518B (zh) * 2016-10-18 2019-05-17 武汉百科药物开发有限公司 一种氯法拉滨的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100695717B1 (ko) * 2000-02-18 2007-03-15 서던리서치인스티튜트 2-클로로-9-(2-데옥시-2-플루오로-베타-디-아라비노퓨라노실)-9에이치-퓨린-6-아민의 합성방법
DE60226447D1 (de) * 2001-08-02 2008-06-19 Ilex Oncology Inc Verfahren zur herstellung von purinnukleosiden
CN101555267A (zh) * 2008-04-09 2009-10-14 杭州容立医药科技有限公司 一种核苷酸类似物克罗拉滨的合成方法
CN101265284B (zh) * 2008-05-07 2011-04-27 深圳万乐药业有限公司 氯法拉滨的合成方法

Also Published As

Publication number Publication date
WO2015118558A2 (fr) 2015-08-13
WO2015118558A3 (fr) 2015-11-05

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