IN2014CH00290A - - Google Patents
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- Publication number
- IN2014CH00290A IN2014CH00290A IN290CH2014A IN2014CH00290A IN 2014CH00290 A IN2014CH00290 A IN 2014CH00290A IN 290CH2014 A IN290CH2014 A IN 290CH2014A IN 2014CH00290 A IN2014CH00290 A IN 2014CH00290A
- Authority
- IN
- India
- Prior art keywords
- rivaroxaban
- highly pure
- crystal modification
- free
- polymorphs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN290CH2014 IN2014CH00290A (es) | 2014-01-23 | 2015-01-19 | |
PCT/IN2015/000031 WO2015111076A2 (en) | 2014-01-23 | 2015-01-19 | Improved processes for the preparation of highly pure rivaroxaban crystal modification i |
US14/601,419 US9469628B2 (en) | 2014-01-23 | 2015-01-21 | Processes for the preparation of highly pure Rivaroxaban crystal modification I |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN290CH2014 IN2014CH00290A (es) | 2014-01-23 | 2015-01-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014CH00290A true IN2014CH00290A (es) | 2015-08-14 |
Family
ID=53544199
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN290CH2014 IN2014CH00290A (es) | 2014-01-23 | 2015-01-19 |
Country Status (3)
Country | Link |
---|---|
US (1) | US9469628B2 (es) |
IN (1) | IN2014CH00290A (es) |
WO (1) | WO2015111076A2 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015111076A2 (en) | 2014-01-23 | 2015-07-30 | Symed Labs Limited | Improved processes for the preparation of highly pure rivaroxaban crystal modification i |
WO2016062828A1 (en) * | 2014-10-22 | 2016-04-28 | Zaklady Farmaceutyczne Polpharma S.A | Process for preparing a polymorph of rivaroxaban |
CN105440028B (zh) * | 2015-12-07 | 2018-03-13 | 石家庄康贺威药业有限公司 | 一种利伐沙班化合物及其制备方法 |
CN105651871A (zh) * | 2015-12-18 | 2016-06-08 | 重庆植恩药业有限公司 | 一种利伐沙班及有关物质的测定方法 |
CN109142601B (zh) * | 2018-10-25 | 2021-03-12 | 重庆华邦胜凯制药有限公司 | 一种分离利伐沙班中间体及其杂质的方法 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19962924A1 (de) * | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
DE102004002044A1 (de) | 2004-01-15 | 2005-08-04 | Bayer Healthcare Ag | Herstellverfahren |
EP1934208B1 (de) * | 2005-10-04 | 2011-03-23 | Bayer Schering Pharma Aktiengesellschaft | Neue polymorphe form von 5-chlor-n-({ ( 5s )-2-0x0-3-[4-( 3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl} -methyl)-2-thiophencarboxamid |
DE102008028071A1 (de) | 2008-06-12 | 2009-12-17 | Bayer Schering Pharma Aktiengesellschaft | Neue Cokristall-Verbindung von Rivaroxaban und Malonsäure |
US20100168111A1 (en) | 2008-12-31 | 2010-07-01 | Apotex Pharmachem Inc. | Polymorphic form of 5 chloro n {[(5s) 2 oxo 3 [4 (3 oxomorpholin 4 yl)phenyl]oxa-zolidin 5 yl]-methyl}thiophene 2 carboxamide |
US7816355B1 (en) | 2009-04-28 | 2010-10-19 | Apotex Pharmachem Inc | Processes for the preparation of rivaroxaban and intermediates thereof |
SI2459555T1 (sl) * | 2009-07-31 | 2022-03-31 | Krka, D.D., Novo Mesto | Postopek kristalizacije rivaroksabana |
EP2521723A1 (en) | 2010-01-04 | 2012-11-14 | Enantia, S.L. | Process for the preparation of rivaroxaban and intermediates thereof |
EP2354128A1 (en) | 2010-02-10 | 2011-08-10 | Sandoz Ag | Method for the preparation of rivaroxaban |
EP2404920A1 (en) | 2010-07-06 | 2012-01-11 | Sandoz AG | Crystalline form of Rivaroxaban dihydrate |
US20130172554A1 (en) | 2010-09-07 | 2013-07-04 | Symed Labs Limited | Processes for the preparation of 4-morpholin-3-one |
WO2012156983A1 (en) | 2011-05-16 | 2012-11-22 | Symed Labs Limited | Processes for the preparation of 5-chloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl) phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophenecarboxamide |
WO2013027225A1 (en) | 2011-08-19 | 2013-02-28 | Symed Labs Limited | Processes for the preparation of 4-{4-[5(s)-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl} morpholin-3-one |
WO2013046211A1 (en) | 2011-09-27 | 2013-04-04 | Symed Labs Limited | Processes for the preparation of 5-chloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl) phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophene-carboxamide and intermediates thereof |
WO2013105100A1 (en) | 2012-01-09 | 2013-07-18 | Symed Labs Limited | Processes for the preparation of 5-chloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophene-carboxamide and intermediates thereof |
WO2013118130A1 (en) | 2012-02-06 | 2013-08-15 | Symed Labs Limited | A process for the preparation of 5-chloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl) phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophene carboxamide |
EP2812329A2 (en) * | 2012-02-06 | 2014-12-17 | Megafine Pharma (P) Ltd. | A process for preparation of rivaroxaban and intermediates thereof |
CN104487436B (zh) * | 2012-05-02 | 2017-05-24 | 信谊实验室有限公司 | 使用中间产物制备利伐沙班的改良方法 |
WO2015111076A2 (en) | 2014-01-23 | 2015-07-30 | Symed Labs Limited | Improved processes for the preparation of highly pure rivaroxaban crystal modification i |
-
2015
- 2015-01-19 WO PCT/IN2015/000031 patent/WO2015111076A2/en active Application Filing
- 2015-01-19 IN IN290CH2014 patent/IN2014CH00290A/en unknown
- 2015-01-21 US US14/601,419 patent/US9469628B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US9469628B2 (en) | 2016-10-18 |
US20150203482A1 (en) | 2015-07-23 |
WO2015111076A2 (en) | 2015-07-30 |
WO2015111076A3 (en) | 2015-11-12 |
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