IN2013MU01431A - - Google Patents
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- Publication number
- IN2013MU01431A IN2013MU01431A IN1431MU2013A IN2013MU01431A IN 2013MU01431 A IN2013MU01431 A IN 2013MU01431A IN 1431MU2013 A IN1431MU2013 A IN 1431MU2013A IN 2013MU01431 A IN2013MU01431 A IN 2013MU01431A
- Authority
- IN
- India
- Prior art keywords
- abstract
- solvents
- derived
- novel
- preparation
- Prior art date
Links
- 238000000034 method Methods 0.000 abstract 4
- 229930195725 Mannitol Natural products 0.000 abstract 1
- 229960001467 bortezomib Drugs 0.000 abstract 1
- -1 bortezomib mannitol ester Chemical class 0.000 abstract 1
- 235000010355 mannitol Nutrition 0.000 abstract 1
- 239000000594 mannitol Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/GB2014/000150 WO2014170628A1 (en) | 2013-04-16 | 2014-04-16 | Process for the preparation of bortezomib mannitol ester |
| IN1431MU2013 IN2013MU01431A (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html) | 2013-04-16 | 2014-04-16 | |
| EP14719344.5A EP2986619A1 (en) | 2013-04-16 | 2014-04-16 | Process for the preparation of bortezomib mannitol ester |
| US14/784,866 US10023611B2 (en) | 2013-04-16 | 2014-04-16 | Process for the preparation of bortezomib mannitol ester |
| CA2909519A CA2909519A1 (en) | 2013-04-16 | 2014-04-16 | Process for the preparation of bortezomib mannitol ester |
| ZA2014/02789A ZA201402789B (en) | 2013-04-16 | 2014-04-16 | Process for the preparation of bortezomib mannitol ester |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1431MU2013 IN2013MU01431A (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html) | 2013-04-16 | 2014-04-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2013MU01431A true IN2013MU01431A (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html) | 2015-06-26 |
Family
ID=50549349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN1431MU2013 IN2013MU01431A (c_deeref_Disk_and_Scratch_Disk_Pools_and_Their_Defaults.html) | 2013-04-16 | 2014-04-16 |
Country Status (6)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10023611B2 (en) | 2013-04-16 | 2018-07-17 | Cipla Limited | Process for the preparation of bortezomib mannitol ester |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112017023250B1 (pt) * | 2015-04-29 | 2023-09-26 | Nanosilical Devices S.R.L | Derivado, sistema de liberação de fármaco, kit, composição farmacêutica e uso do referido derivado |
| WO2016205790A2 (en) | 2015-06-19 | 2016-12-22 | Hanlin Scientific, Inc. | Chiral specific boron-containing compounds and their use in treating cancer or amyloidosis |
| PT109941B (pt) * | 2017-03-02 | 2021-02-09 | Hovione Farmaciência, S.A. | Conjugados de boro multifuncionais com uma estrutura tripodal, composições farmacêuticas e processos de preparação dos mesmos |
| EP3908258A4 (en) * | 2019-01-11 | 2022-09-28 | Intas Pharmaceuticals Ltd. | METHOD FOR PREPARING A STABLE PHARMACEUTICAL COMPOSITION OF BORTEZOMIB |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4499082A (en) | 1983-12-05 | 1985-02-12 | E. I. Du Pont De Nemours And Company | α-Aminoboronic acid peptides |
| US5250720A (en) | 1987-06-05 | 1993-10-05 | The Dupont Merck Pharmaceutical Company | Intermediates for preparing peptide boronic acid inhibitors of trypsin-like proteases |
| US5187157A (en) | 1987-06-05 | 1993-02-16 | Du Pont Merck Pharmaceutical Company | Peptide boronic acid inhibitors of trypsin-like proteases |
| US5242904A (en) | 1987-06-05 | 1993-09-07 | The Dupont Merck Pharmaceutical Company | Peptide boronic acid inhibitors of trypsin-like proteases |
| EP0315574A3 (de) | 1987-11-05 | 1990-08-22 | Hoechst Aktiengesellschaft | Renin-Inhibitoren |
| US5106948A (en) | 1988-05-27 | 1992-04-21 | Mao Foundation For Medical Education And Research | Cytotoxic boronic acid peptide analogs |
| US6083903A (en) | 1994-10-28 | 2000-07-04 | Leukosite, Inc. | Boronic ester and acid compounds, synthesis and uses |
| PT979096E (pt) | 1997-02-15 | 2003-09-30 | Millennium Pharm Inc | Tratamento de enfartes atraves da inibicao de nf-kb |
| AU9580098A (en) | 1997-09-25 | 1999-04-12 | Millennium Pharmaceuticals, Inc. | Proteasome inhibitors, ubiquitin pathway inhibitors or agents that interfere with the activation of nf-(k)b via the ubiquitin proteasome pathway to treat inflammatory and autoimmune diseases |
| ES2571219T3 (es) * | 2001-01-25 | 2024-09-23 | The United States Of America Represented By The Sec Dep Of Health And Human Services | Formulación de compuestos de ácido borónico |
| PT4008721T (pt) | 2004-03-30 | 2024-03-21 | Millennium Pharm Inc | Síntese de compostos de ácido e de éster borónico |
| WO2008075376A1 (en) * | 2006-12-18 | 2008-06-26 | Natco Pharma Limited | Polymorphic forms of bortezomib and process for their preparation |
| WO2009004350A1 (en) | 2007-07-03 | 2009-01-08 | Pliva Hrvatska D.O.O. | Methods for preparing bortezomib and intermediates used in its manufacture |
| WO2009036281A2 (en) | 2007-09-12 | 2009-03-19 | Dr. Reddy's Laboratories Ltd. | Bortezomib and process for producing same |
| WO2010039762A2 (en) * | 2008-10-01 | 2010-04-08 | Dr. Reddy's Laboratories Ltd. | Pharmaceutical compositions comprising boronic acid compounds |
| US8785674B2 (en) | 2009-06-19 | 2014-07-22 | Lek Pharmaceuticals D.D. | Process for hydrogenation of halogenoalkenes without dehalogenation |
| CA2785300A1 (en) | 2009-12-22 | 2011-07-21 | Cephalon, Inc. | Proteasome inhibitors and processes for their preparation, purification and use |
| US20130085277A1 (en) | 2010-02-09 | 2013-04-04 | Ranbaxy Laboratories Limited | Process for the preparation of bortezomib |
| ES2548256T3 (es) | 2010-10-14 | 2015-10-15 | Synthon Bv | Proceso para la preparación de bortezomib y los intermedios para el proceso |
| AU2013316838A1 (en) | 2012-09-11 | 2015-04-09 | Cipla Limited | Process for preparing of Bortezomib |
| CA2909519A1 (en) | 2013-04-16 | 2014-10-23 | Cipla Limited | Process for the preparation of bortezomib mannitol ester |
-
2014
- 2014-04-16 CA CA2909519A patent/CA2909519A1/en not_active Abandoned
- 2014-04-16 US US14/784,866 patent/US10023611B2/en not_active Expired - Fee Related
- 2014-04-16 EP EP14719344.5A patent/EP2986619A1/en not_active Withdrawn
- 2014-04-16 ZA ZA2014/02789A patent/ZA201402789B/en unknown
- 2014-04-16 WO PCT/GB2014/000150 patent/WO2014170628A1/en active Application Filing
- 2014-04-16 IN IN1431MU2013 patent/IN2013MU01431A/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10023611B2 (en) | 2013-04-16 | 2018-07-17 | Cipla Limited | Process for the preparation of bortezomib mannitol ester |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014170628A1 (en) | 2014-10-23 |
| US10023611B2 (en) | 2018-07-17 |
| EP2986619A1 (en) | 2016-02-24 |
| ZA201402789B (en) | 2015-11-25 |
| CA2909519A1 (en) | 2014-10-23 |
| WO2014170628A8 (en) | 2014-12-18 |
| US20160075736A1 (en) | 2016-03-17 |