IN2013MN01547A - - Google Patents

Download PDF

Info

Publication number
IN2013MN01547A
IN2013MN01547A IN1547MUN2013A IN2013MN01547A IN 2013MN01547 A IN2013MN01547 A IN 2013MN01547A IN 1547MUN2013 A IN1547MUN2013 A IN 1547MUN2013A IN 2013MN01547 A IN2013MN01547 A IN 2013MN01547A
Authority
IN
India
Prior art keywords
wounds
treating
molecular target
ptprk
protein
Prior art date
Application number
Other languages
English (en)
Inventor
Wenguo Jiang
Keith Harding
Original Assignee
Univ Cardiff
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Cardiff filed Critical Univ Cardiff
Publication of IN2013MN01547A publication Critical patent/IN2013MN01547A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/29Antimony or bismuth compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/11Antisense
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/12Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
    • C12N2310/121Hammerhead
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering N.A.
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00Applications; Uses
    • C12N2320/30Special therapeutic applications
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00Applications; Uses
    • C12N2320/30Special therapeutic applications
    • C12N2320/31Combination therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2330/00Production
    • C12N2330/30Production chemically synthesised

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IN1547MUN2013 2011-03-08 2012-02-17 IN2013MN01547A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1103898.1A GB201103898D0 (en) 2011-03-08 2011-03-08 Molecular targets for healing or treating wounds
PCT/GB2012/050362 WO2012120269A1 (fr) 2011-03-08 2012-02-17 Cibles moléculaires pour la guérison ou le traitement des blessures

Publications (1)

Publication Number Publication Date
IN2013MN01547A true IN2013MN01547A (fr) 2015-06-12

Family

ID=43923365

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1547MUN2013 IN2013MN01547A (fr) 2011-03-08 2012-02-17

Country Status (10)

Country Link
US (2) US20140213629A1 (fr)
EP (1) EP2683823B1 (fr)
JP (1) JP5986116B2 (fr)
CN (1) CN103443276B (fr)
AU (1) AU2012226593B2 (fr)
CA (1) CA2829010A1 (fr)
GB (2) GB201103898D0 (fr)
HK (1) HK1192904A1 (fr)
IN (1) IN2013MN01547A (fr)
WO (1) WO2012120269A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014183062A1 (fr) * 2013-05-10 2014-11-13 La Jolla Institute For Allergy And Immunology Traitements de maladies autoimmunes
WO2015019125A1 (fr) * 2013-08-05 2015-02-12 Societe De Developpement Et De Recherche Industrielle Cibles moléculaires destinées au traitement des blessures, en particulier des blessures chroniques
WO2020176790A1 (fr) * 2019-02-27 2020-09-03 Fred Hutchinson Cancer Research Center Compositions d'hydrogel et méthodes de traitement de cancers

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6204000B1 (en) 1995-04-28 2001-03-20 The United States Of America As Represented By The Department Of Health And Human Services Diagnostic methods and gene therapy using reagents derived from the human metastasis suppressor gene KAI1
KR100366439B1 (ko) * 2000-02-21 2003-01-09 주식회사 대웅 상피세포 성장인자를 유효성분으로 하는 안정한 약제학적조성물
US20050215629A1 (en) 2001-09-07 2005-09-29 Taolin Yi PTPase inhibitors and methods of using the same
AU2002339904A1 (en) * 2001-09-07 2003-09-09 The Cleveland Clinic Foundation Therapeutic compositions and methods useful in modulating protein tyrosine phosphatases
US7844214B2 (en) 2002-03-02 2010-11-30 Nokia Corporation System and method for broadband digital broadcasting
EP1482966B1 (fr) * 2002-03-12 2014-05-14 Bio-Click Technologies Ltd Methode et composition de traitement de lesions cutanees avec un facteur de croissance epidermique
US20040009597A1 (en) * 2002-07-03 2004-01-15 Isis Pharmaceuticals Inc. Antisense modulation of PTPRK expression
CA2506619A1 (fr) 2002-11-18 2004-08-19 Thomas W. Hodge Lignees cellulaires et sequences d'acides nucleiques hotes associees a des maladies infectieuses
JP2006517092A (ja) 2002-11-27 2006-07-20 アルテシアン セラピューティック,インコーポレイティド 心不全遺伝子の決定及び治療薬スクリーニング
GB2396106B (en) * 2002-12-12 2006-11-15 Johnson & Johnson Medical Ltd Wound dressings comprising enzyme inhibitors
EP1670946B1 (fr) 2003-09-19 2012-11-07 bioTheranostics, Inc. Prevision du resultat d'un traitement contre le cancer du sein
US20050170445A1 (en) 2004-01-07 2005-08-04 Duke University Methods of establishing profiles for use in evaluating wound healing and biocompatibility of implant materials and microarrays useful therefor
WO2006108225A1 (fr) 2005-04-11 2006-10-19 Garvan Institute Of Medical Research Procede de criblage pour des composes qui modulent la proliferation cellulaire
US20090203006A1 (en) 2006-05-01 2009-08-13 New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Biological markers of chronic wound tissue and methods of using for criteria in surgical debridement
WO2008005276A2 (fr) * 2006-06-30 2008-01-10 Directcontact Llc Dispositif médical/système destiné à administrer un médicament pour soigner des blessures et prévenir une inflammation ou une maladie
CA2707900A1 (fr) 2007-12-07 2009-06-18 Oregon Health & Science University Procedes permettant de determiner si un sujet reagira a un inhibiteur bcr-abl
US20110305703A1 (en) 2008-12-08 2011-12-15 Vegenics Pty Limited Isolated vegf-c and vegf-d peptides and uses thereof
WO2010085606A1 (fr) 2009-01-22 2010-07-29 Case Western Reserve University Biomarqueurs protéiniques et cibles thérapeutiques pour l'arthrose
CN101671729B (zh) 2009-09-07 2012-09-05 张力建 用于肺癌治疗方案选择和/或预后评估的基因群、基因芯片和检测试剂盒
GB0916124D0 (en) 2009-09-15 2009-10-28 Univ Cardiff Method and kit for the classification and prognosis of wounds

Also Published As

Publication number Publication date
JP2014511392A (ja) 2014-05-15
CN103443276A (zh) 2013-12-11
EP2683823B1 (fr) 2016-07-20
US20160331716A1 (en) 2016-11-17
US20140213629A1 (en) 2014-07-31
GB201103898D0 (en) 2011-04-20
HK1192904A1 (zh) 2014-09-05
CA2829010A1 (fr) 2012-09-13
WO2012120269A1 (fr) 2012-09-13
JP5986116B2 (ja) 2016-09-06
US9782381B2 (en) 2017-10-10
AU2012226593B2 (en) 2016-06-02
EP2683823A1 (fr) 2014-01-15
GB201314859D0 (en) 2013-10-02
CN103443276B (zh) 2016-09-28
GB2502017A (en) 2013-11-13
AU2012226593A1 (en) 2013-09-12

Similar Documents

Publication Publication Date Title
CY1117655T1 (el) Παραγοντες οι οποιοι επαγουν αποπτωση για την αντιμετωπιση καρκινου και ανοσολογικων και αυτοανοσων νοσηματων
AU2011328009A8 (en) Compounds and methods for treating pain
CY1116728T1 (el) Παραγοντες οι οποιοι επαγουν αποπτωση για την αντιμετωπιση καρκινου και ανοσολογικων και αυτοανοσων νοσηματων
BR112013006673A2 (pt) produtos terapêuticos para câncer de mama
EP3195868A3 (fr) Utilisation thérapeutique d'un agoniste de tlr, et polythérapie
MX2012013731A (es) Vacunas que comprenden colesterol y cpg como moleculas portadoras-adyuvantes unicas.
MX366130B (es) Inhibidores bivalentes de las proteinas iap y métodos terapéuticos que usan los mismos.
EP3747457A3 (fr) Protéine du facteur 1, protéine du facteur 2 et leurs inhibiteurs destinés à être utilisés dans le traitement ou la prévention de maladies
WO2015054619A3 (fr) Utilisation d'un inhibiteur de pcsk9 pour traiter l'hyperlipidémie
WO2013169864A3 (fr) Tétrahydro[1,8]naphtyridine-sulfonamide et composés apparentés pour utilisation en tant qu'agonistes de rorγ et dans le traitement d'une maladie
BR112015000776A2 (pt) Agentes de ligação à rspo3 e usos dos mesmos
BR112013020159A2 (pt) método para inibir células tumorais de hamartoma
MA40057A (fr) Traitement thérapeutique de maladie cutanée au moyen de micro-organismes cutanés commensaux recombinants
MX2019007057A (es) Composiciones de adenovirus.
EP3818991A3 (fr) Compositions et procédés de traitement de maladies
WO2016090024A3 (fr) Polythérapie pour le traitement du cancer
MX2013008530A (es) Peptidos a base de lactoferrina humana que tienen actividad antiinflamatoria.
MX2014001393A (es) 3-(bifenil-3-il)-4-hidroxi-8-metoxi-1-azaespiro[4.5]dec-3-en-2-on as sustituidas.
MX2015007719A (es) Terapia dirigida del receptor del factor de crecimiento epidermico (egfr) de trastornos neurologicos y dolor.
MY173174A (en) Short bio-active peptides for promoting wound healing
IN2013MN01547A (fr)
MX2015005733A (es) Compuestos triciclicos para usarse en el tratamiento y/o control de obesidad.
MX2013002539A (es) Sobrenadante condicionado por leucocitos activados y usos para la cicatrizacion de heridas.
MX2016004212A (es) Inhibidor de tor cinasa en la prevencion o tratamiento de cancer caracterizado por mutaciones genicas.
TN2013000336A1 (en) 5s,8s)-3-(4'-chlor-3'-fluoro-4-methylbiphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one (compound a) for therapy.