IN2013DE03085A - - Google Patents
Info
- Publication number
- IN2013DE03085A IN2013DE03085A IN3085DE2013A IN2013DE03085A IN 2013DE03085 A IN2013DE03085 A IN 2013DE03085A IN 3085DE2013 A IN3085DE2013 A IN 3085DE2013A IN 2013DE03085 A IN2013DE03085 A IN 2013DE03085A
- Authority
- IN
- India
- Prior art keywords
- manufacturing
- ophthalmic
- formulation
- present
- pharmaceutical
- Prior art date
Links
- 238000000034 method Methods 0.000 abstract 3
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 229940122072 Carbonic anhydrase inhibitor Drugs 0.000 abstract 1
- 208000010412 Glaucoma Diseases 0.000 abstract 1
- 206010030043 Ocular hypertension Diseases 0.000 abstract 1
- 229960000686 benzalkonium chloride Drugs 0.000 abstract 1
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 abstract 1
- 239000002876 beta blocker Substances 0.000 abstract 1
- 239000003489 carbonate dehydratase inhibitor Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EA201690532A EA030535B1 (ru) | 2013-10-17 | 2014-10-13 | Не содержащий консерванта офтальмологический фармацевтический состав |
| PCT/IB2014/065262 WO2015056149A1 (en) | 2013-10-17 | 2014-10-13 | Preservative-free ophthalmic pharmaceutical formulation |
| UAA201603600A UA116273C2 (uk) | 2013-10-17 | 2014-10-13 | Офтальмологічний фармацевтичний склад, що не містить консерванта |
| EP14811969.6A EP3057576A1 (en) | 2013-10-17 | 2014-10-13 | Preservative-free ophthalmic pharmaceutical formulation |
| US15/028,930 US9801813B2 (en) | 2013-10-17 | 2014-10-13 | Preservative-free ophthalmic pharmaceutical formulation |
| IN3085DE2013 IN2013DE03085A (enrdf_load_stackoverflow) | 2013-10-17 | 2014-10-13 | |
| CA2924562A CA2924562A1 (en) | 2013-10-17 | 2014-10-13 | Preservative-free ophthalmic pharmaceutical formulation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3085DE2013 IN2013DE03085A (enrdf_load_stackoverflow) | 2013-10-17 | 2014-10-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2013DE03085A true IN2013DE03085A (enrdf_load_stackoverflow) | 2015-04-24 |
Family
ID=52023563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN3085DE2013 IN2013DE03085A (enrdf_load_stackoverflow) | 2013-10-17 | 2014-10-13 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9801813B2 (enrdf_load_stackoverflow) |
| EP (1) | EP3057576A1 (enrdf_load_stackoverflow) |
| CA (1) | CA2924562A1 (enrdf_load_stackoverflow) |
| EA (1) | EA030535B1 (enrdf_load_stackoverflow) |
| IN (1) | IN2013DE03085A (enrdf_load_stackoverflow) |
| UA (1) | UA116273C2 (enrdf_load_stackoverflow) |
| WO (1) | WO2015056149A1 (enrdf_load_stackoverflow) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230143595A1 (en) * | 2020-03-31 | 2023-05-11 | Sentiss Pharma Private Limited | A sterilization process of timolol gel forming solution through aseptic filtration |
| US12186430B2 (en) | 2020-04-07 | 2025-01-07 | Combangio, Inc. | Lyophilized mesenchymal stem cell derived secretome and uses thereof |
| EP4281040A4 (en) * | 2021-01-21 | 2024-11-27 | Kowa Company, Ltd. | Methods of treating fuchs endothelial corneal dystrophy after descemetorhexis |
| CN112920138B (zh) * | 2021-01-27 | 2023-03-07 | 成都摩尔生物医药有限公司 | 一种噻吗洛尔杂质的制备方法 |
| KR102808906B1 (ko) | 2021-06-18 | 2025-05-19 | 대우제약 주식회사 | 고점도 점안제를 무균여과하는 방법 |
| EP4309644A1 (en) * | 2022-07-22 | 2024-01-24 | Warszawskie Zaklady Farmaceutyczne Polfa S.A. | Preservative-free ophthalmic composition comprising an antiglaucoma agent |
| AU2023338294A1 (en) * | 2022-09-07 | 2025-03-20 | Combangio, Inc. | Preparation and purification methods for mesenchymal stem cell derived secretome |
| CN116139151B (zh) * | 2022-12-22 | 2025-02-11 | 武汉科福新药有限责任公司 | 一种含有噻吗洛尔的局部用药物组合物及其制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4438123A (en) * | 1980-03-04 | 1984-03-20 | Merck & Co., Inc. | Ophthalmic compositions of carbonic anhydrase inhibitors for topical application in the treatment of elevated intraocular pressure |
| US4797413A (en) | 1986-05-14 | 1989-01-10 | Merck & Co., Inc. | Thieno thiopyran sulfonamide derivatives, pharmaceutical compositions and use |
| US4731368A (en) | 1986-12-08 | 1988-03-15 | Merck & Co., Inc. | Thienopyridine sulfonamides and their ophthalmological formulation |
| US4847289A (en) | 1987-06-08 | 1989-07-11 | Merck & Co., Inc. | Thiophene sulfonamide antiglaucoma agents |
| US5378703A (en) | 1990-04-09 | 1995-01-03 | Alcon Laboratories, Inc. | Sulfonamides useful as carbonic anhydrase inhibitors |
| US5153192A (en) | 1990-04-09 | 1992-10-06 | Alcon Laboratories, Inc. | Thiophene sulfonamides useful as carbonic anhydrase inhibitors |
| IE911192A1 (en) | 1990-04-12 | 1991-10-23 | Merck & Co Inc | Substituted aromatic sulfonamides as antiglaucoma agents |
| US6071904A (en) * | 1996-12-11 | 2000-06-06 | Alcon Laboratories, Inc. | Process for manufacturing ophthalmic suspensions |
| IT1395044B1 (it) | 2009-06-30 | 2012-09-05 | Marzoli Spa | Apritoio a flusso assiale |
| TW201109325A (en) * | 2009-07-30 | 2011-03-16 | Wakamoto Pharma Co Ltd | Aqueous composition for eye drops |
| MX2012006401A (es) * | 2009-12-03 | 2012-07-10 | Lupin Ltd | Proceso para preparar composiciones oftalmicas farmaceuticas. |
-
2014
- 2014-10-13 IN IN3085DE2013 patent/IN2013DE03085A/en unknown
- 2014-10-13 WO PCT/IB2014/065262 patent/WO2015056149A1/en active Application Filing
- 2014-10-13 CA CA2924562A patent/CA2924562A1/en not_active Abandoned
- 2014-10-13 UA UAA201603600A patent/UA116273C2/uk unknown
- 2014-10-13 US US15/028,930 patent/US9801813B2/en active Active
- 2014-10-13 EA EA201690532A patent/EA030535B1/ru not_active IP Right Cessation
- 2014-10-13 EP EP14811969.6A patent/EP3057576A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP3057576A1 (en) | 2016-08-24 |
| CA2924562A1 (en) | 2015-04-23 |
| UA116273C2 (uk) | 2018-02-26 |
| EA030535B1 (ru) | 2018-08-31 |
| EA201690532A1 (ru) | 2016-09-30 |
| US20160235665A1 (en) | 2016-08-18 |
| US9801813B2 (en) | 2017-10-31 |
| WO2015056149A1 (en) | 2015-04-23 |
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