MX2012006401A - Proceso para preparar composiciones oftalmicas farmaceuticas. - Google Patents
Proceso para preparar composiciones oftalmicas farmaceuticas.Info
- Publication number
- MX2012006401A MX2012006401A MX2012006401A MX2012006401A MX2012006401A MX 2012006401 A MX2012006401 A MX 2012006401A MX 2012006401 A MX2012006401 A MX 2012006401A MX 2012006401 A MX2012006401 A MX 2012006401A MX 2012006401 A MX2012006401 A MX 2012006401A
- Authority
- MX
- Mexico
- Prior art keywords
- preparing
- slurry
- compositions
- carbonic anhydrase
- anhydrase inhibitor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Composiciones oftálmicas farmacéuticas que comprenden ingrediente(s) activos como inhibidor de anhidrasa carbónica (CAl) o combinaciones y procesos para realizar dichas composiciones y el uso de estas composiciones en poblaciones de pacientes que incluyen poblaciones pediátricas. Un proceso para preparar una composición oftálmica que comprende un inhibidor de anhidrasa carbónica que comprende a) preparar una suspensión que comprende un inhibidor de anhidrasa carbónica y un surfactante; b) preparar una suspensión de polímero que comprende un polímero y agua; c) preparar una solución que comprende la tonicidad y agentes conservadores; d) mezclar la suspensión del polímero del paso b y la solución del paso c, para formar un concentrado del excipiente líquido y ajustar un pH; e) agregar la suspensión del paso a, al concentrado del excipiente líquido del paso d y mezclar para homogenizar; f) realizar mediante autoclave la mezcla del paso e; g) medir la mezcla del paso f, bajo condición aséptica.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1415KO2009 | 2009-12-03 | ||
PCT/IN2010/000784 WO2011067791A2 (en) | 2009-12-03 | 2010-12-02 | Process for preparing pharmaceutical ophthalmic compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2012006401A true MX2012006401A (es) | 2012-07-10 |
Family
ID=44115377
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012006401A MX2012006401A (es) | 2009-12-03 | 2010-12-02 | Proceso para preparar composiciones oftalmicas farmaceuticas. |
Country Status (6)
Country | Link |
---|---|
US (1) | US8614210B2 (es) |
EP (1) | EP2506878A2 (es) |
JP (1) | JP5558582B2 (es) |
AU (1) | AU2010325632B2 (es) |
MX (1) | MX2012006401A (es) |
WO (1) | WO2011067791A2 (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013175285A1 (en) | 2012-05-21 | 2013-11-28 | Aurobindo Pharma Limited | Process for preparing ophthalmic suspension of brinzolamde |
WO2014057499A1 (en) | 2012-10-11 | 2014-04-17 | Indoco Remedies Limited | A process for manufacturing sterile brinzolamide ophthalmic suspension |
US20140377210A1 (en) * | 2013-06-21 | 2014-12-25 | Gnt, Llc | Artificial tear compositions |
EA030535B1 (ru) * | 2013-10-17 | 2018-08-31 | Сентисс Фарма Прайвет Лимитед | Не содержащий консерванта офтальмологический фармацевтический состав |
WO2015068105A1 (en) * | 2013-11-08 | 2015-05-14 | Sentiss Pharma Private Limited | An improved process for manufacturing sterile ophthalmic pharmaceutical suspensions |
UA118576C2 (uk) * | 2014-01-24 | 2019-02-11 | Сентис Фарма Прайвет Лімітед | Фармацевтична композиція, яка містить бринзоламід |
PL407710A1 (pl) * | 2014-03-28 | 2015-10-12 | Instytut Farmaceutyczny | Sposób wytwarzania preparatu kropli do oczu w postaci zawiesiny zawierającej brynzolamid i preparat wytworzony tym sposobem |
JP6279395B2 (ja) * | 2014-05-01 | 2018-02-14 | 東亜薬品株式会社 | ブリンゾラミド懸濁性点眼液組成物の製造方法 |
NZ728131A (en) | 2014-07-11 | 2017-09-29 | Fujifilm Corp | Aqueous ophthalmic composition |
WO2016063184A1 (en) * | 2014-10-20 | 2016-04-28 | Sentiss Pharma Private Limited | Ophthalmic solution |
EP3511020B1 (en) * | 2014-12-02 | 2021-01-20 | Novartis AG | Manufacture of surfactant-containing compositions |
US20170189352A1 (en) | 2015-03-13 | 2017-07-06 | Par Pharmaceutical, Inc. | Epinephrine formulations |
US9119876B1 (en) | 2015-03-13 | 2015-09-01 | Par Pharmaceutical, Inc. | Epinephrine formulations |
WO2020072979A1 (en) * | 2018-10-04 | 2020-04-09 | Miraki Innovation Think Tank Llc | Slurry and solution compositions |
KR102271247B1 (ko) * | 2020-11-04 | 2021-06-30 | 삼천당제약주식회사 | 안과용 현탁액 조성물의 제조방법 |
JP2024506384A (ja) * | 2021-02-10 | 2024-02-13 | イオリクス セラピューティクス,インコーポレーテッド | ロフルミラストの眼科的送達方法 |
CN116867480A (zh) * | 2021-02-10 | 2023-10-10 | 洛利克斯治疗有限公司 | 眼部递送罗氟司特的方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5378703A (en) | 1990-04-09 | 1995-01-03 | Alcon Laboratories, Inc. | Sulfonamides useful as carbonic anhydrase inhibitors |
US6071904A (en) * | 1996-12-11 | 2000-06-06 | Alcon Laboratories, Inc. | Process for manufacturing ophthalmic suspensions |
US6258350B1 (en) * | 1999-01-20 | 2001-07-10 | Alcon Manufacturing, Ltd. | Sustained release ophthalmic formulation |
JP4766653B2 (ja) * | 2005-01-28 | 2011-09-07 | 株式会社林原生物化学研究所 | 眼科用医薬組成物 |
JP5080445B2 (ja) * | 2005-04-13 | 2012-11-21 | アボット ゲーエムベーハー ウント コー. カーゲー | 超微粒子懸濁液及び超微粒子を穏やかに製造する方法並びにその使用 |
US20070077303A1 (en) * | 2005-09-30 | 2007-04-05 | Azaam Alli | Methods for providing oxidatively stable ophthalmic compositions |
-
2010
- 2010-12-02 EP EP10801718.7A patent/EP2506878A2/en not_active Withdrawn
- 2010-12-02 WO PCT/IN2010/000784 patent/WO2011067791A2/en active Application Filing
- 2010-12-02 JP JP2012541629A patent/JP5558582B2/ja not_active Expired - Fee Related
- 2010-12-02 AU AU2010325632A patent/AU2010325632B2/en not_active Ceased
- 2010-12-02 MX MX2012006401A patent/MX2012006401A/es not_active Application Discontinuation
- 2010-12-02 US US13/513,335 patent/US8614210B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20120283252A1 (en) | 2012-11-08 |
WO2011067791A2 (en) | 2011-06-09 |
AU2010325632A1 (en) | 2012-06-21 |
JP5558582B2 (ja) | 2014-07-23 |
WO2011067791A3 (en) | 2011-09-09 |
US8614210B2 (en) | 2013-12-24 |
JP2013512894A (ja) | 2013-04-18 |
EP2506878A2 (en) | 2012-10-10 |
AU2010325632B2 (en) | 2014-01-30 |
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Legal Events
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FA | Abandonment or withdrawal |